[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100602506":3},{"organization":4,"armGroups":7,"interventions":26,"overallOfficials":43,"centralContacts":62,"locations":68,"responsibleParty":87,"collaborators":90,"id":93,"slug":94,"hasResults":95,"nctId":96,"briefTitle":97,"officialTitle":98,"acronym":99,"eligibilityCriteria":100,"healthyVolunteers":95,"sex":101,"minAge":102,"maxAge":32,"enrollmentInfo":103,"targetDuration":32,"studyType":106,"phases":107,"briefSummary":109,"conditions":110,"keywords":114,"overallStatus":119,"whyStopped":32,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},{"fullName":5,"class":6},"Chelsea and Westminster NHS Foundation Trust","OTHER",[8,14,20],{"label":9,"type":10,"description":11,"interventionNames":12},"Arm 1: Electroacupuncture (EA) Group Experimental","EXPERIMENTAL","Arm 1: Electroacupuncture (EA) Group Arm Type: Experimental Description: Participants in this group will receive electroacupuncture treatment targeting sacral and lower abdominal acupuncture points traditionally used for overactive bladder (OAB). Sterile, single-use acupuncture needles will be inserted and connected to an electroacupuncture device that delivers a low-frequency electrical current.\n\nDuration: 12 weekly sessions over 12 weeks Setting: Delivered by trained pelvic health physiotherapists in an outpatient hospital setting.\n\nIntervention:",[13],"Device: Name: Electroacupuncture (EA) Type: Device-based acupuncture therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Arm 2: Percutaneous Tibial Nerve Stimulation (PTNS) Group","ACTIVE_COMPARATOR","Arm Type: Active Comparator Description: Participants in this group will receive percutaneous tibial nerve stimulation, a standard treatment for OAB. A fine needle electrode is inserted near the ankle to stimulate the tibial nerve, transmitting signals to the sacral nerve plexus that controls bladder function.\n\nDuration: 12 weekly sessions over 12 weeks Setting: Delivered by trained clinicians in an outpatient setting.",[19],"Device: Neuromodulation therapy",{"label":21,"type":22,"description":23,"interventionNames":24},"Arm 3: Sham Acupuncture (Control) Group","SHAM_COMPARATOR","Description: Needles will be placed superficially (2-3 mm depth) at non-acupuncture points located approximately 1-2 cm lateral to the true sacral and abdominal treatment points, avoiding recognised meridian locations.\n\nElectrical Stimulation Electrode clips will be attached to needles, and the electroacupuncture device will be activated without delivering electrical output (no current transmission). Visual and auditory cues will be maintained to preserve credibility.\n\nThis is used as a control to assess the true efficacy of EA compared to placebo.\n\nDuration: 12 weekly sessions over 12 weeks Setting: Delivered by trained physiotherapists using standardised placebo protocols.",[25],"Device: Sham Acupuncture",[27,33,39],{"type":28,"name":29,"description":30,"armGroupLabels":31,"otherNames":32},"DEVICE","Name: Electroacupuncture (EA) Type: Device-based acupuncture therapy","Description: Insertion of acupuncture needles at specific points with electrical stimulation (2 Hz) for 30 minutes per session.",[9],null,{"type":28,"name":34,"description":35,"armGroupLabels":36,"otherNames":37},"Neuromodulation therapy","Type: Neuromodulation therapy\n\nDescription: Insertion of a needle electrode near the medial malleolus with low-voltage electrical stimulation (20 Hz) applied for 30 minutes per session.",[15],[38],"Percutaneous Tibial Nerve Stimulation (PTNS)",{"type":28,"name":40,"description":41,"armGroupLabels":42,"otherNames":32},"Sham Acupuncture","Type: Placebo\n\nDescription: Non-invasive, non-penetrating placebo needles placed at the same points as in the EA group, without electrical stimulation, for 30 minutes per session.",[21],[44,48,51,54,58],{"name":45,"affiliation":46,"role":47},"Leila Janani, PhD","Imperial College London-Advanced Research Fellow \u002F Senior Clinical Trials Statistician Deputy Head of Trial Methodology","STUDY_CHAIR",{"name":49,"affiliation":50,"role":47},"Deepa Dr Abichandani","Senior Lecturer in Physiotherapy Employability Lead for School of Allied and Community Health London South Bank Universit",{"name":52,"affiliation":53,"role":47},"Mark Pro. Johnson","Senior Lecturer, Consultant in Obstetrics and Obstetric Medicine Charing Cross Hospital. And Chelsea and Westminster NHS Trust Imperial College London Clinical Chair in Obstetrics Department of Metabolism, Digestion an",{"name":55,"affiliation":56,"role":57},"Rufus Mr. Cartwright","Uro-gynaecologist consultant and Honorary Clinical Senior Lecturer institute of Reproductive and Developmental Biology, Hammersmith Campus and Celsea and Westminster NHS Trust Gynaecology and Departm","STUDY_DIRECTOR",{"name":59,"affiliation":60,"role":61},"Elmas X Court","Chelsea and Westminster Hospital and Imperial College London","PRINCIPAL_INVESTIGATOR",[63],{"name":64,"role":65,"phone":66,"phoneExt":32,"email":67},"Elmas Court","CONTACT","+447538355975","elmas.court@nhs.net",[69],{"facility":70,"status":32,"city":71,"state":32,"zip":72,"country":73,"countryCode":74,"cosmosGeoPoint":75,"geoPoint":80,"contacts":81},"Chelsea and Westminster hospital NHS foundation Trust","London","SW10 9NH","United Kingdom","UK",{"type":76,"coordinates":77},"Point",[78,79],-0.12574,51.50853,{"lat":79,"lon":78},[82,84],{"name":83,"role":65,"phone":66,"phoneExt":32,"email":67},"Elmas Court, BSc (hons) Physiotherapy",{"name":55,"role":65,"phone":85,"phoneExt":32,"email":86},"+447720544811","rufus.cartwright@nhs.net",{"type":61,"investigatorFullName":88,"investigatorTitle":89,"investigatorAffiliation":5,"oldNameTitle":32,"oldOrganization":32},"Elmas","Pelvic Health Physiotherapist",[91],{"name":92,"class":6},"Imperial College London","100602506","electroacupuncture-as-a-treatment-for-refractory-overactive-bladder-100602506",false,"NCT07124390","Electroacupuncture as a Treatment for Refractory Overactive Bladder","Electroacupuncture as a Treatment for Refractory Overactive Bladder: A Feasibility \u002FPilot Randomized Controlled Trial","EAOAB","Inclusion Criteria:\n\nParticipants must meet all of the following criteria:\n\n* Female adults aged 18 years or older.\n* Diagnosed with overactive bladder syndrome (ICIQ-OAB score ≥10).\n* Symptoms present for at least three months and refractory to first-line treatments.\n* Willing to refrain from starting new bladder-related treatments during the study period.\n* Able and willing to provide written informed consent.\n\nExclusion Criteria:\n\n* Participants meeting any of the following criteria will be excluded:\n\n  * Pregnant or planning pregnancy during the study period.\n  * Bleeding disorders.\n  * Severe needle phobia.\n  * Presence of a pacemaker.\n  * Active cancer diagnosis.\n  * Active urinary tract infections or other urological conditions requiring urgent intervention.\n  * Participation in another clinical trial for bladder dysfunction within the past six months.\n  * Neurological conditions affecting continence (e.g., diabetic neuropathy, multiple sclerosis, Parkinson's disease).\n  * Life-threatening infections.\n  * Severe cognitive deficits, unconsciousness, dementia (e.g., Alzheimer's or other neurodegenerative diseases).\n  * History of incontinence surgery.\n  * Previous acupuncture for OAB within the past two months.\n  * History of thromboses.\n  * Recovering from or suffering from a serious illness or major surgery.","FEMALE","18 Years",{"count":104,"type":105},32,"ESTIMATED","INTERVENTIONAL",[108],"NA","This study is a single-site feasibility randomised controlled trial evaluating the feasibility and acceptability of electroacupuncture (EA), percutaneous tibial nerve stimulation (PTNS), and sham electroacupuncture in women with refractory overactive bladder (OAB) who have not achieved satisfactory improvement following standard pelvic health physiotherapy.\n\nThe primary aim is to determine whether a larger definitive trial is feasible by assessing recruitment, consent, retention, treatment adherence, data completeness, intervention delivery, blinding credibility, safety, and participant acceptability.\n\nThirty-six participants will be randomly allocated to receive electroacupuncture, PTNS, or sham electroacupuncture over a 12-week treatment period. Outcome assessments will be completed at baseline, 6 weeks, 12 weeks, 6 months, and 12 months.\n\nThe findings will inform the design of a future definitive randomised controlled trial and contribute to the evidence base for non-pharmacological treatment options for overactive bladder.",[111,112,113],"Over Active Bladder","Urinary Incontinence (UI)","Nocturia",[115,116,117,118],"Electric-Acupuncture","Acupuncture","PTNS","Neuromodulation","NOT_YET_RECRUITING","2026-06-13",{"date":122,"type":123},"2026-06-16","ACTUAL",{"date":125,"type":105},"2026-07-01",{"date":127,"type":105},"2027-07-30",{"name":5,"class":6},1]