[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554197":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":40,"responsibleParty":126,"collaborators":23,"id":129,"slug":130,"hasResults":131,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":23,"eligibilityCriteria":135,"healthyVolunteers":131,"sex":136,"minAge":23,"maxAge":23,"enrollmentInfo":137,"targetDuration":23,"studyType":140,"phases":141,"briefSummary":143,"conditions":144,"keywords":23,"overallStatus":147,"whyStopped":23,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":157},{"fullName":5,"class":6},"Guang'anmen Hospital of China Academy of Chinese Medical Sciences","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Electroacupuncture group","EXPERIMENTAL","Needles will be inserted at 11 acupoints. Acupoints will be added electrical stimulation via a low-frequency neural regulator (electrical stimulator) respectively with a disperse-dense wave after insertion of all needles. Twenty-minute treatments will be delivered three times weekly for 8 weeks.",[13],"Other: Electroacupuncture group",{"label":15,"type":6,"description":16,"interventionNames":17},"Micro-acupuncture group","11 needles will be inserted at acupoints with 1-3 mm in depth. The acupoints will then be connected to the electrical stimulator in accordance with the electroacupuncture group. The frequency of the electroacupuncture is the same as that of the electroacupuncture group, which is briefly energized at the beginning for 30s.Twenty-minute treatments will be delivered three times weekly for 8 weeks.",[18],"Other: Micro-acupuncture group",[20,24],{"type":6,"name":9,"description":21,"armGroupLabels":22,"otherNames":23},"Electroacupuncture treatment consists of conventional acupuncture and electrical stimulation. After acupuncture, the electrical stimulation is continuously stimulated for 20 minutes.",[9],null,{"type":6,"name":15,"description":25,"armGroupLabels":26,"otherNames":23},"After acupuncture, the electrical stimulation is continuously stimulated for 20 minutes. Electrical stimulation is applied briefly for the first 30 seconds.",[15],[28],{"name":29,"affiliation":5,"role":30},"Baohui Jia","PRINCIPAL_INVESTIGATOR",[32,36],{"name":29,"role":33,"phone":34,"phoneExt":23,"email":35},"CONTACT","010-88001454","jiabaohui2504@gamyy.cn",{"name":37,"role":33,"phone":38,"phoneExt":23,"email":39},"Ran Li","18801094908","lcgxliran@163.com",[41,59,70,77,87,98,113],{"facility":42,"status":23,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Beijing United Family Rehabilitation Hospital","Beijing","Beijing Municipality","100015","China","CN",{"type":49,"coordinates":50},"Point",[51,52],116.39723,39.9075,{"lat":52,"lon":51},[55],{"name":56,"role":33,"phone":57,"phoneExt":23,"email":58},"Dongmei Li","13717850887","13717850887@139.com",{"facility":60,"status":23,"city":43,"state":44,"zip":61,"country":46,"countryCode":47,"cosmosGeoPoint":62,"geoPoint":64,"contacts":65},"China-Japan Friendship Hospital","100029",{"type":49,"coordinates":63},[51,52],{"lat":52,"lon":51},[66],{"name":67,"role":33,"phone":68,"phoneExt":23,"email":69},"Rongxing Shi","18610153099","2243111436@qq.com",{"facility":5,"status":23,"city":43,"state":44,"zip":71,"country":46,"countryCode":47,"cosmosGeoPoint":72,"geoPoint":74,"contacts":75},"100053",{"type":49,"coordinates":73},[51,52],{"lat":52,"lon":51},[76],{"name":37,"role":33,"phone":34,"phoneExt":23,"email":39},{"facility":78,"status":23,"city":43,"state":44,"zip":71,"country":46,"countryCode":47,"cosmosGeoPoint":79,"geoPoint":81,"contacts":82},"Xuanwu Hospital of Capital Medical University",{"type":49,"coordinates":80},[51,52],{"lat":52,"lon":51},[83],{"name":84,"role":33,"phone":85,"phoneExt":23,"email":86},"Aihong Zhou","010-83192333","zahxwh@163.com",{"facility":88,"status":23,"city":43,"state":44,"zip":89,"country":46,"countryCode":47,"cosmosGeoPoint":90,"geoPoint":92,"contacts":93},"Beijing Geriatric Hospital","100095",{"type":49,"coordinates":91},[51,52],{"lat":52,"lon":51},[94],{"name":95,"role":33,"phone":96,"phoneExt":23,"email":97},"Jihui Lv","13520094838","lvjihui@139.com",{"facility":99,"status":23,"city":100,"state":101,"zip":102,"country":46,"countryCode":47,"cosmosGeoPoint":103,"geoPoint":107,"contacts":108},"Fujian University of Traditional Chinese Medicine","Fuzhou","Fujian","350122",{"type":49,"coordinates":104},[105,106],119.30611,26.06139,{"lat":106,"lon":105},[109],{"name":110,"role":33,"phone":111,"phoneExt":23,"email":112},"Ying Xu","0591-22861815","aaa8858@qq.com",{"facility":114,"status":23,"city":115,"state":116,"zip":117,"country":46,"countryCode":47,"cosmosGeoPoint":118,"geoPoint":122,"contacts":123},"The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine","Harbin","Heilongjiang","150001",{"type":49,"coordinates":119},[120,121],126.65,45.75,{"lat":121,"lon":120},[124],{"name":125,"role":33,"phone":23,"phoneExt":23,"email":23},"Li Zhang",{"type":30,"investigatorFullName":127,"investigatorTitle":128,"investigatorAffiliation":5,"oldNameTitle":23,"oldOrganization":23},"Bao-Hui Jia","Director of rehabilitation Medicine","100554197","electroacupuncture-for-the-treatment-of-agitated-symptoms-of-alzheimers-disease-100554197",false,"NCT06495957","Electroacupuncture for the Treatment of Agitated Symptoms of Alzheimer's Disease","Evaluation of Therapeutic Effect and Brain Mechanism of Electroacupuncture in Treating Agitation Symptoms of Alzheimer's Disease","Inclusion Criteria:\n\n1. Meet the revised draft diagnostic criteria for Alzheimer's disease published by the Alzheimer's Association in 2023\n2. Meet the 2023 IPA definition of agitated symptoms of cognitive impairment\n3. Cohen Mansfield Agitation Inventory (CMAI)≥45 points\n4. Have been on stable anti-AD medication (cholinesterase inhibitors, etc.) for more than 1 month\n5. If taking antipsychotics, the medication regimen for agitation (antipsychotics) is stable for 1 month prior to randomization\n6. Subject and legal guardian and caregiver sign informed consent.\n\nExclusion Criteria:\n\n1. There are contraindications for acupuncture treatment, such as the tendency of acupoint bleeding or allergy to metal\n2. Received electroacupuncture treatment in the past 2 weeks\n3. At the time of the screening, participants are participating in other clinical trials or planned to participate in other clinical trials in the next 17 weeks.","ALL",{"count":138,"type":139},224,"ESTIMATED","INTERVENTIONAL",[142],"NA","The purpose of this study is to evaluate the efficacy of electroacupuncture in the treatment of agitation symptoms in patients with Alzheimer's disease (AD). Meanwhile the study aims to explore the brain central mechanism of electroacupuncture in the treatment of agitation symptoms in patients with AD by using resting state functional magnetic resonance technology.",[145,146],"Agitation Associated With Alzheimer's Dementia","Alzheimer's Dementia","NOT_YET_RECRUITING","2024-07-03",{"date":150,"type":151},"2024-07-11","ACTUAL",{"date":153,"type":139},"2024-07-20",{"date":155,"type":139},"2027-10-31",{"name":5,"class":6},7]