[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100457404":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":20,"centralContacts":24,"locations":29,"responsibleParty":45,"collaborators":48,"id":52,"slug":53,"hasResults":54,"nctId":55,"briefTitle":56,"officialTitle":56,"acronym":19,"eligibilityCriteria":57,"healthyVolunteers":54,"sex":58,"minAge":19,"maxAge":19,"enrollmentInfo":59,"targetDuration":19,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":19,"overallStatus":31,"whyStopped":19,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"Boston Children's Hospital","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"RV mapping","Participants will undergo a sinus rhythm electroanatomic RV substrate map prior to TPVR.",[12],"Diagnostic Test: Electroanatomic substrate mapping",[14],{"type":15,"name":16,"description":17,"armGroupLabels":18,"otherNames":19},"DIAGNOSTIC_TEST","Electroanatomic substrate mapping","Participants will undergo a sinus rhythm RV substrate map using the HD Grid catheter (Abbott) and the Ensite X electroanatomic mapping system (Abbott) prior to TPVR.",[9],null,[21],{"name":22,"affiliation":5,"role":23},"Edward T O'Leary, MD","PRINCIPAL_INVESTIGATOR",[25],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},"CONTACT","617-355-7833","edward.oleary@cardio.chboston.org",[30],{"facility":5,"status":31,"city":32,"state":33,"zip":34,"country":35,"countryCode":36,"cosmosGeoPoint":37,"geoPoint":42,"contacts":43},"RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":38,"coordinates":39},"Point",[40,41],-71.05977,42.35843,{"lat":41,"lon":40},[44],{"name":22,"role":26,"phone":27,"phoneExt":19,"email":28},{"type":23,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":19,"oldOrganization":19},"Edward O'Leary","Staff Physician",[49],{"name":50,"class":51},"Abbott","INDUSTRY","100457404","electroanatomic-interactions-between-transcatheter-pulmonary-valve-prostheses-and-anatomic-isthmuses-in-repaired-tetralogy-of-fallot-100457404",false,"NCT05236153","Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot","Inclusion Criteria:\n\n* Diagnosis of tetralogy of Fallot (TOF) or double outlet right ventricle (DORV)\n* Referred for transcatheter pulmonary valve replacement (TPVR) per routine clinical indications\n* Weight \\>=25 kg","ALL",{"count":60,"type":61},60,"ESTIMATED","INTERVENTIONAL",[64],"NA","Individuals with repaired Tetralogy of Fallot (rTOF) remain at risk for sudden cardiac death from ventricular tachycardia (VT). Transcatheter pulmonary valve replacement (TPVR) indications continue to broaden, yet its capability to reduce the risk of VT and sudden cardiac death remains unknown. Thus, in a cohort of participants with rTOF who are presenting for TPVR the investigators intend to: (1) quantify and localize right ventricular (RV) isthmuses with abnormal voltage and\u002For conduction velocity; (2) identify which RV isthmuses are at risk of being \"jailed\" by TPV prostheses; and (3) explore the feasibility of omnipolar technology to characterize wavefront directionality and differentiate slow conduction from conduction block.",[67,68,69],"Tetralogy of Fallot","Ventricular Tachycardia","Sudden Cardiac Death","2023-02-06",{"date":72,"type":73},"2023-02-08","ACTUAL",{"date":75,"type":73},"2022-11-04",{"date":77,"type":61},"2024-01-01",{"name":5,"class":6},1]