[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617857":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":18,"centralContacts":30,"locations":36,"responsibleParty":53,"collaborators":18,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":63,"eligibilityCriteria":64,"healthyVolunteers":59,"sex":65,"minAge":66,"maxAge":18,"enrollmentInfo":67,"targetDuration":18,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":18,"overallStatus":39,"whyStopped":18,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Charles University, Czech Republic","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Blue group","EXPERIMENTAL","active group",[13,14],"Device: Electroconvulsive therapy","Device: Transcranial Magnetic Stimulation",{"label":16,"type":17,"description":18,"interventionNames":19},"Red group","SHAM_COMPARATOR",null,[13],[21,26],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":18},"DEVICE","Electroconvulsive therapy","transcranial magnetic stimulation in intermitent theta burst stimulation protocol plus electroconvulsive therapy",[9,16],{"type":22,"name":27,"description":28,"armGroupLabels":29,"otherNames":18},"Transcranial Magnetic Stimulation","Transcranial magnetic stimulation, intermitent theta burst stimulation or sham TMS",[9],[31],{"name":32,"role":33,"phone":34,"phoneExt":18,"email":35},"Daniel Divacky","CONTACT","+420 224 965 357","daniel.divacky@lf1.cuni.cz",[37],{"facility":38,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":18,"cosmosGeoPoint":44,"geoPoint":49,"contacts":50},"General University Hospital, Psychiatry department","RECRUITING","Prague","Czech","120 39","Czechia",{"type":45,"coordinates":46},"Point",[47,48],14.42076,50.08804,{"lat":48,"lon":47},[51],{"name":32,"role":33,"phone":52,"phoneExt":18,"email":35},"+ 420 224 965 357",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"PRINCIPAL_INVESTIGATOR","Daniel Divácký","MD","100617857","electroconvulsive-therapy-augmented-with-transcranial-magnetic-stimulation-for-treatment-resistant-depression-100617857",false,"NCT07324070","Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression","New Methods Electroconvulsive Therapy Augmentation","RMTSECT2","Inclusion Criteria:\n\n* Age equal to 18 or higher\n* MADRS (Montgomery-Asberg Depression Scale) qual or higher than 20\n* Major depressive disorder according to ICD 10\n\nExclusion Criteria:\n\n* Other axis 1 disorder (for example schizofrenia, addiction, etc.)\n* No dementia\n* ECT in the last 3 months\n* TMS in the last 3 months\n* Psychotic disease or symptoms\n* Ppregnancy or lactation\n* Any neurological disease (for example epilepsy, etc.)\n* Participation in another clinical trial within the last 30 days\n* somatic condition which contraindicates ECT","ALL","18 Years",{"count":68,"type":69},50,"ESTIMATED","INTERVENTIONAL",[72],"NA","The RTMSECT2 study was design to compare the application of electroconvulsive therapy augmented by transcranial magnetic stimulation. Subject will be compared both within groups and in group using psychometric scales and different deliver energy",[75,76],"Major Depressive Disorder (MDD)","Treatment Resistant Depression (TRD)","2026-01-06",{"date":79,"type":80},"2026-01-07","ACTUAL",{"date":82,"type":80},"2026-01-05",{"date":84,"type":69},"2029-01-05",{"name":5,"class":6},1]