[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569310":3},{"organization":4,"armGroups":7,"interventions":24,"overallOfficials":11,"centralContacts":38,"locations":44,"responsibleParty":60,"collaborators":11,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":68,"eligibilityCriteria":69,"healthyVolunteers":64,"sex":70,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":11,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":11,"overallStatus":47,"whyStopped":11,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Ljubljana","OTHER",[8,14,19],{"label":9,"type":10,"description":11,"interventionNames":12},"EOS","EXPERIMENTAL",null,[13],"Other: Electrolysed saline rinse",{"label":15,"type":16,"description":11,"interventionNames":17},"CHX","ACTIVE_COMPARATOR",[18],"Device: Chlorhexidine 0,12%",{"label":20,"type":21,"description":11,"interventionNames":22},"Placebo - distilled water","PLACEBO_COMPARATOR",[23],"Device: Distilled water group",[25,29,34],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"Electrolysed saline rinse","EOS ph = 7, 200 ppm free available Chlorine",[9],{"type":30,"name":31,"description":32,"armGroupLabels":33,"otherNames":11},"DEVICE","Distilled water group","Distilled water will be used as a negative placebo mouth-rinse",[20],{"type":30,"name":35,"description":36,"armGroupLabels":37,"otherNames":11},"Chlorhexidine 0,12%","0.12% pharmaceutical formulation will be used as an active comparator",[15],[39],{"name":40,"role":41,"phone":42,"phoneExt":11,"email":43},"Rok Gašperšič, PhD","CONTACT","0038615224889","rok.gaspersic@mf.uni-lj.si",[45],{"facility":46,"status":47,"city":48,"state":11,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"University Medical Centre Ljubljana","RECRUITING","Ljubljana","1000","Slovenia","SI",{"type":53,"coordinates":54},"Point",[55,56],14.50513,46.05108,{"lat":56,"lon":55},[59],{"name":40,"role":41,"phone":42,"phoneExt":11,"email":43},{"type":61,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100569310","electrolysed-saline-rinse-as-an-adjunct-for-treatment-of-chronic-periodontitis-100569310",false,"NCT06692582","Electrolysed Saline Rinse as an Adjunct for Treatment of Chronic Periodontitis","Influence of Adjunctive Electrolysed Saline Rinse in Stage III Periodontitis Patients","EOSPERIO","Inclusion Criteria:\n\nClinical attachment loss ≥ 5 mm on at least two teeth in two different jaw quadrants; presence of stable occlusion and at least 16 teeth, among which at least 12 teeth are suitable for evaluation (excluding wisdom teeth, teeth with orthodontic wires, bridges, crowns, and implants).\n\nExclusion Criteria:\n\nWe will exclude individuals who: suffer from chronic systemic diseases (diabetes, cancer, HIV infection, metabolic bone diseases, and diseases that interfere with wound healing processes); are undergoing radiation or chemotherapy; are taking immunosuppressants, antiepileptic drugs, calcium antagonists, nonsteroidal anti-inflammatory drugs; have been treated with antibiotics in the past 12 months; have a known allergy to CHX; have undergone scaling and root planing or surgical periodontal treatment in the past year; are pregnant or breastfeeding.","ALL","18 Years","80 Years",{"count":74,"type":75},60,"ESTIMATED","INTERVENTIONAL",[78],"NA","The study will be conducted as a prospective, double-blind, parallel, randomized, placebo-controlled study at the Dental Clinic of University Medical Centre Ljubljana. It will involve a one-month test period, during which the test subjects will use either placebo, Electrolysed Oxidising Saline (EOS) or chlorhexidine (CHX) in the form of a mouthwash as an adjunct to the non-surgical treatment of chronic periodontitis (i.e. root planing and scaling). The study will include 60 subjects selected from consecutively scheduled patients referred by their personal dentists for periodontal treatment at the Dental Clinic of University Medical Centre Ljubljana.",[81],"Periodontitis","2026-05-05",{"date":84,"type":85},"2026-05-11","ACTUAL",{"date":87,"type":85},"2024-06-06",{"date":89,"type":75},"2026-12-06",{"name":5,"class":6},1]