[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603840":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":25,"locations":30,"responsibleParty":50,"collaborators":25,"id":54,"slug":55,"hasResults":56,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":56,"sex":61,"minAge":62,"maxAge":63,"enrollmentInfo":64,"targetDuration":25,"studyType":67,"phases":68,"briefSummary":70,"conditions":71,"keywords":76,"overallStatus":33,"whyStopped":25,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Wroclaw Medical University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"PFA group","ACTIVE_COMPARATOR","Patients in this arm will undergo 3D-mpping guided re-ablation with the PFA catheter",[13],"Procedure: Pulsed field ablation of reccurent atrial arrythmia",{"label":15,"type":10,"description":16,"interventionNames":17},"RFA group","Patients in this arm will undergo 3D-mpping guided re-ablation with RFA catheter",[18],"Procedure: Radiofrequency ablation of reccurent atrial arrythmia (standard of care)",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Pulsed field ablation of reccurent atrial arrythmia","Substrate modification strategy based ablation of reccurent atrial arrythmia following pulmonary viens isolation employing pulsed field ablation with 3D guidance and high density mapping",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Radiofrequency ablation of reccurent atrial arrythmia (standard of care)","Standard radiofrequncy ablation of reccurent atrial arrythmia following pulmonary vien isolation employing substrate modification strategy",[15],[31],{"facility":32,"status":33,"city":34,"state":25,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Clinical Department of Cardio, Jan Mikulicz Radecki University Hospital in Wroclaw","RECRUITING","Wroclaw","50-556","Poland","PL",{"type":39,"coordinates":40},"Point",[41,42],17.03006,51.10286,{"lat":42,"lon":41},[45],{"name":46,"role":47,"phone":48,"phoneExt":25,"email":49},"Stanislaw Tubek Tubek, MD, PhD","CONTACT","+48 71 733 11 12","stanislaw.tubek@umw.edu.pl",{"type":51,"investigatorFullName":52,"investigatorTitle":53,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Stanisław Tubek","MD, PhD","100603840","electroporation-vs-radiofrequency-ablation-guided-by-3d-imaging-in-repeat-procedures-for-atrial-fibrillation-100603840",false,"NCT07141745","Electroporation vs. Radiofrequency Ablation Guided by 3D Imaging in Repeat Procedures for Atrial Fibrillation","ERA-rePVI","Inclusion Criteria:\n\nDocumented recurrence of AF or atypical atrial flutter after prior PVI Eligibility for re-PVI\n\nExclusion Criteria:\n\nLeft ventricular ejection fraction \\\u003C 30% Left atrial volume index (LAVI) \\> 72 mL\u002Fm² Untreated hyperthyroidism Hypertrophic cardiomyopathy Severe valvular heart disease","ALL","18 Years","85 Years",{"count":65,"type":66},250,"ESTIMATED","INTERVENTIONAL",[69],"NA","This is a prospective, randomized clinical trial evaluating the efficacy and safety of two techniques for repeat catheter ablation in patients with recurrent atrial fibrillation (AF): thermal energy ablation (radiofrequency) and non-thermal electroporation (pulsed field ablation), both guided by 3D imaging systems.\n\nPatients undergoing repeat AF ablation will be randomly assigned to receive either thermal or electroporation ablation, performed according to standard hospital protocols. No additional invasive procedures are required. Following the ablation, participants will attend follow-up visits at 3, 6, and 12 months, including medical history review, physical examination, 12-lead ECG, and 24-hour Holter monitoring. Unscheduled ECG assessments will also be available if arrhythmia symptoms occur.\n\nAll study-related procedures are non-invasive and align with routine post-ablation care. Risks are limited to those typically associated with standard AF ablation procedures.\n\nThe main benefit of participation is close, structured follow-up by experienced electrophysiologists, allowing for early detection of arrhythmia recurrence and timely medical intervention when necessary.\n\nParticipant confidentiality and data protection will be ensured in accordance with GDPR regulations.",[72,73,74,75],"Atrial Fibrillation (AF)","Ablation Techniques","Radiofrequency Catheter Ablation","Pulsed Field Ablation",[77,75,74,78],"Atrial fibrillation re-ablation","Atrial firbillation reccurence","2025-08-26",{"date":81,"type":82},"2025-08-27","ACTUAL",{"date":84,"type":66},"2025-08-30",{"date":86,"type":66},"2028-10-01",{"name":5,"class":6},1]