[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559632":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":27,"centralContacts":32,"locations":41,"responsibleParty":74,"collaborators":77,"id":80,"slug":81,"hasResults":82,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":10,"eligibilityCriteria":86,"healthyVolunteers":87,"sex":88,"minAge":89,"maxAge":10,"enrollmentInfo":90,"targetDuration":10,"studyType":93,"phases":10,"briefSummary":94,"conditions":95,"keywords":101,"overallStatus":44,"whyStopped":10,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":120},{"fullName":5,"class":6},"University of Aarhus","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Amyotrophic Lateral Sclerosis (ALS)",null,"People diagnosed or suspected of having the neurodegenerative disease Amyotrophic Lateral Sclerosis (ALS)",[13],"Other: Emotion Discrimination Task (EDT)",{"label":15,"type":10,"description":16,"interventionNames":17},"Neuromuscular","People diagnosed with a neuromuscular disease other than ALS",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Control","Healthy people",[13],[23],{"type":6,"name":24,"description":25,"armGroupLabels":26,"otherNames":10},"Emotion Discrimination Task (EDT)","It estimates the subjective bias and sensitivity in discriminating between happy and angry facial expressions of different intensities of emotional expression",[9,19,15],[28],{"name":29,"affiliation":30,"role":31},"Mia B Heintzelmann, Cand.med","Department of Neurology, Aarhus University Hospital","PRINCIPAL_INVESTIGATOR",[33,37],{"name":29,"role":34,"phone":35,"phoneExt":10,"email":36},"CONTACT","78454255","minielse@rm.dk",{"name":38,"role":34,"phone":39,"phoneExt":10,"email":40},"Camilla Hakala, Bach.psych","26332857","caha@cfin.au.dk",[42,58],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Aarhus University Hospital","RECRUITING","Aarhus","Central Jutland","8200","Denmark","DK",{"type":51,"coordinates":52},"Point",[53,54],10.21076,56.15674,{"lat":54,"lon":53},[57],{"name":29,"role":34,"phone":35,"phoneExt":10,"email":36},{"facility":59,"status":60,"city":61,"state":62,"zip":63,"country":48,"countryCode":49,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"Aalborg University Hospital","NOT_YET_RECRUITING","Aalborg","Region Nordjulland","9000",{"type":51,"coordinates":65},[66,67],9.9187,57.048,{"lat":67,"lon":66},[70],{"name":71,"role":34,"phone":72,"phoneExt":10,"email":73},"Jakob U Blicher, Ph.D","78469939","jbli@cfin.au.dk",{"type":31,"investigatorFullName":75,"investigatorTitle":76,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Mia Heintzelmann","Ph.d. fellow",[78,79],{"name":43,"class":6},{"name":59,"class":6},"100559632","emotion-processing-among-patients-with-als-100559632",false,"NCT06566651","Emotion Processing Among Patients With ALS","Emotion and Interoception Processing in ALS","Inclusion Criteria:\n\n* ALS patients, ambulant and hospitalized\n\n  * Able to give informed consent\n  * Diagnosed with ALS or probable ALS according to the existing revision of the El Escorial Criteria 21,22.\n* Patients with a peripheral neuromuscular disease, ambulant and hospitalized\n\n  * Able to give informed consent\n  * Diagnosed with a peripheral neuromuscular disease, that does not affect CNS, including but not limited to Myasthenia Gravis and polyneuropathy\n* Healthy controls\n\n  * Able to give informed consent\n  * Age and gender matched to ALS patients\n\nExclusion Criteria:\n\n* All Participants\n\n  * Other severe medical, neurological, or psychiatric disorders\n  * Visual impairment to an extent that interferes with the ability to perform of the test\n  * Severe motor or cognitive deficits, to the extent that the test-task cannot be performed\n  * Alcohol or drug abuse to an extent the interferes with task performance\n* Patients with a peripheral neuromuscular disease\n\n  ● Familial predisposition to ALS\n* Healthy controls\n\n  * Familial predisposition to ALS (first degree relatives)\n  * Medical treatment that affects the central nervous system (e.g., antidepressants)",true,"ALL","18 Years",{"count":91,"type":92},180,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the emotional perception in people with ALS disease compared to people with other neuromuscular disease and healthy controls. The main questions it aims to answer are:\n\n* How people with ALS judge happy and angry faces and what their \"insight\" into these judgements are like\n* How their autonomic responses differ from the other two test group Participants will asked to judge if a face presents a happy emotion or angry emotion.\n\nResearchers will compare the ALS group responses with neuromuscular diseases group and healthy control group responses to see if the ALS group judge more happy faces than angry.",[96,97,98,99,100],"Amyotrophic Lateral Sclerosis","Neuromuscular Diseases","ALS","Motor Neuron Disease","MND (Motor Neurone DIsease)",[96,97,102,103,104,105,106,107,108,98,109,110],"Emotion Perception","Emotion Processing","Emotion Recognition","Autonomic Responses","Respiratory Responses","Heart rate","Emotion Discrimination Task","Motorneuron disease","MND","2024-08-20",{"date":113,"type":114},"2024-08-22","ACTUAL",{"date":116,"type":114},"2023-12-15",{"date":118,"type":92},"2026-06-30",{"name":5,"class":6},2]