[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100593048":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":42,"responsibleParty":58,"collaborators":60,"id":66,"slug":67,"hasResults":68,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":26,"eligibilityCriteria":71,"healthyVolunteers":68,"sex":72,"minAge":73,"maxAge":26,"enrollmentInfo":74,"targetDuration":26,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":88,"overallStatus":91,"whyStopped":26,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"Loma Linda University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Standard of Care (SOC)","ACTIVE_COMPARATOR","Participants will receive SOC, which includes medications for addiction therapy (MAT) (including but not limited to buprenorphine, naltrexone, bupropion, etc.) weekly counseling, and monthly clinic visits with addiction specialists.",[13],"Other: Standard addiction counseling and medical therapy",{"label":15,"type":16,"description":17,"interventionNames":18},"Emotional Brain Training (EBT) and Standard of Care (SOC)","EXPERIMENTAL","This group will receive all the components of SOC plus EBT counseling:\n\nA. The components below will be completed daily and is estimated to take 25 minutes:\n\ni. \\[10 1-minute spiral ups (SU) - an EBT specific, app-directed methodology of emotional regulation\\], plus; ii. 5 minutes via telephone for a group peer connection iii. 10 minutes online\u002Fphone app coursework\u002Fvideo\n\nB. Once a week: participants will participate in a 60 minute small-group telephone meeting for accountability and support C. Once a week: participants will participate in at least 3 30-minute Spiral Up (SU) groups\u002Fweek to practice the skills. These are available online daily.",[19,13],"Behavioral: Emotional Brain Training",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"BEHAVIORAL","Emotional Brain Training","Emotional Brain Training (EBT) is a structured, neuroscience-based behavioral intervention that focuses on rewiring the brain's stress-related circuits to promote emotional resilience, self-regulation, and lasting behavioral change. This behavioral intervention has not been implemented in addiction treatments in the past. Unlike traditional therapies that primarily target cognitive processes or symptom management, EBT directly addresses the physiological and emotional root causes of maladaptive behaviors by engaging the brain's natural neuroplasticity mechanisms. EBT integrates rapid emotional processing tools, peer-to-peer support, clinician-facilitated sessions, and mobile app-based self-care to systematically transition brain circuits from stress-reactive to stress-resilient states.",[15],null,{"type":6,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Standard addiction counseling and medical therapy","Participants will receive standard counseling (including but not limited to cognitive behavioral therapy, motivational interviewing, etc.), which does not include EBT, in addition to medications for addiction treatment (including but not limited to buprenorphine, naltrexone, bupropion, etc.).",[15,9],[32,38],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},"Brenda Boyle, DNP","CONTACT","909-382-7100","4432","bboyle@sachealth.org",{"name":39,"role":34,"phone":40,"phoneExt":26,"email":41},"Lori D Karan, MD","650-270-5025","lori.karan@va.gov",[43],{"facility":44,"status":26,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Addiction Recovery Clinic at SAC Health","San Bernardino","California","92408","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-117.28977,34.10834,{"lat":54,"lon":53},[57],{"name":33,"role":34,"phone":35,"phoneExt":36,"email":37},{"type":59,"investigatorFullName":26,"investigatorTitle":26,"investigatorAffiliation":26,"oldNameTitle":26,"oldOrganization":26},"SPONSOR",[61,63],{"name":62,"class":6},"University of California, San Francisco",{"name":64,"class":65},"Social Action for Health","UNKNOWN","100593048","emotional-brain-training-for-addiction-medicine-treatment---a-pilot-study-100593048",false,"NCT07001371","Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study","Inclusion Criteria:\n\n* Age 18 years old or older\n* Patient can speak and read English\n* Patient who receives regular MAT care at SAC Health\n* Patients who have regular and reliable cellular and\u002For reliable internet connection\n* Patients who are willing to spend average of 25 minutes per day and attend weekly group meetings\n* Patients willing to actively participate in group sessions\n* Opioid use disorder, at least in early remission\n* Alcohol use disorder, at least in early remission\n* Methamphetamine use disorder, at least in early remission\n* Cocaine use disorder, at least in early remission\n* Anxiolytic use disorder, at least in early remission\n* Cannabis use disorder\n* Tobacco use disorder\n\nExclusion Criteria:\n\n* Age \\\u003C18 years old\n* Patient does not speak or read English\n* Patients who do not seek regular MAT care at SAC Health\n* Patients with inconsistent or no access to cellular or internet connection\n* Any disorder that is uncontrolled\n* Any substance use disorder not in at least early remission\n* Any patient with complications related to use disorder\n* Patients enrolled in the Coachella Valley Rescue Mission patients a part of SAC Health\n* Anyone who, in the opinion of the investigators, would be unable to participate in an 8-week trial","ALL","18 Years",{"count":75,"type":76},54,"ESTIMATED","INTERVENTIONAL",[79],"NA","The goal of this clinical trial is to determine whether Emotional Brain Training (EBT), a behavioral modification method, can help manage stress and health problems related to addiction. EBT teaches skills to deactivate harmful circuits (automatic reactions) and activate healing circuits to quickly shift mood from negative to positive. Participants in the EBT group will receive focused, intensive instruction on using these skills to rewire unwanted brain circuits, with the aim of achieving lasting improvements in emotional health and quality of life. The study will assess whether EBT is an effective tool when added to standard of care (SOC), which includes medications for addiction treatment (MAT).\n\nResearchers will compare changes in stress, anxiety, and cravings after 8 weeks of EBT plus SOC versus SOC alone.\n\nParticipants:\n\n* will either continue receiving standard treatments (SOC) at the Addiction Recovery Clinic (ARC) at SAC Health in San Bernardino\n* or receive both EBT and SOC at ARC\n* in the SOC group will continue monthly visits at ARC and weekly counseling\n* in the EBT plus SOC group will continue monthly visits and weekly counseling at ARC, along with weekly EBT group sessions by telephone\n* will complete online assessments at weeks 0, 4, and 8 Upon completion of the study, all participants will resume SOC",[82,83,84,85,86,87],"Cannabis Use Disorder","Stimulant Use Disorder","Opioid Use Disorder","Tobacco Use Disorder","Alcohol Use Disorder","Sedative, Hypnotic, or Anxiolytic Use Disorders",[89,90],"early remission","sustained remission","NOT_YET_RECRUITING","2026-04-21",{"date":94,"type":95},"2026-04-23","ACTUAL",{"date":97,"type":76},"2026-08",{"date":99,"type":76},"2027-08",{"name":5,"class":6},1]