[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100525337":3},{"organization":4,"armGroups":7,"interventions":17,"overallOfficials":10,"centralContacts":23,"locations":33,"responsibleParty":53,"collaborators":57,"id":77,"slug":78,"hasResults":79,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":10,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":85,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":91,"studyType":92,"phases":10,"briefSummary":93,"conditions":94,"keywords":100,"overallStatus":36,"whyStopped":10,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":107,"completionDateStruct":109,"leadSponsor":111,"locationsCount":112},{"fullName":5,"class":6},"Shanghai Changzheng Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Total en bloc spondylectomy for spinal oligometastases",null,"Based on the medical history, physical signs, and imaging examination results, a definitely diagnosis of spinal oligometastasis tumor was made and perform a Total en bloc spondylectomy.",[13],"Procedure: total en bloc spondylectomy",{"label":15,"type":10,"description":16,"interventionNames":10},"Separation surgery combined with radiotherapy for spinal oligometastases","Based on the medical history, physical signs, and imaging examination results, a definitely diagnosis of spinal oligometastasis tumor was made and perform a Separation surgery. After surgical recovery, take a radiotherapy.",[18],{"type":19,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"PROCEDURE","total en bloc spondylectomy","Total enbloc resection (TES) is one of the most challenging surgeries in spinal surgery and a classic surgical method. It not only relieve spinal cord compression and delays tumor recurrence, but also prolongs patient survival, significantly reduces hand surgery trauma, and improves surgical safety. However, for cases with extensive tumor invasion, methods such as separation surgery should be used to relieve spinal cord nerve compression, rebuild spinal stability, and provide conditions for postoperative radiotherapy.",[9],[24,29],{"name":25,"role":26,"phone":27,"phoneExt":10,"email":28},"Jianru Xiao, Doctor","CONTACT","+86 13701785283","jianruxiao83@163.com",{"name":30,"role":26,"phone":31,"phoneExt":10,"email":32},"Wei Xu, Doctor","+86 13761278657","xuweichangzheng@hotmail.com",[34],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Shanghai Changzheng hospital","RECRUITING","Shanghai","Shanghai Municipality","200003","China","CN",{"type":43,"coordinates":44},"Point",[45,46],121.45806,31.22222,{"lat":46,"lon":45},[49,51],{"name":25,"role":26,"phone":50,"phoneExt":10,"email":28},"13701785283",{"name":30,"role":26,"phone":52,"phoneExt":10,"email":32},"13761278657",{"type":54,"investigatorFullName":55,"investigatorTitle":56,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Jianru Xiao","shanghaiczh",[58,60,62,65,67,69,71,73,75],{"name":59,"class":6},"Peking University Third Hospital",{"name":61,"class":6},"Peking University People's Hospital",{"name":63,"class":64},"Henan Cancer Hospital","OTHER_GOV",{"name":66,"class":6},"First Affiliated Hospital, Sun Yat-Sen University",{"name":68,"class":6},"Sun Yat-sen University",{"name":70,"class":6},"Zhejiang University",{"name":72,"class":6},"Tianjin Hospital",{"name":74,"class":6},"The First Affiliated Hospital of Nanchang University",{"name":76,"class":64},"The Third Affiliated Hospital of Southern Medical University","100525337","en-bloc-resection-versus-separation-surgery-combined-with-radiotherapy-for-the-treatment-of-spinal-oligometastatic-tumor-100525337",false,"NCT06120426","En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor.","En Bloc Resection Versus Separation Surgery Combined With Radiotherapy for the Treatment of Spinal Oligometastatic Tumor-A Multi-center, Prospective, Randomized, Controlled Study.","Inclusion Criteria:\n\n* 1\\) Be able to sign written informed consent.\n* 2\\) Age range from 18 to 75 years old, regardless of gender.\n* 3\\) Within conservative treatment, the patient still has uncontrollable pain, metastatic cancer lesions that still progress, spinal instability\u002Fpotential instability, or symptoms of spinal cord\u002Fnerve compression.\n* 4\\) After the patient underwent Positron Emission Tomography-Computed Tomography (PET-CT) examination, it was indicated that there were no more than 3 metastatic organs and no more than 5 metastatic lesions in the whole body of cancer. Among them, there was at least 1 spinal metastasis and at most 5 spinal metastases.\n* 5\\) Imaging examinations (enhanced MRI, enhanced CT, X-ray) indicate the presence of spinal metastasis.\n* 6\\) The expected survival period is ≥ 6 months.\n* 7)No other surgical contraindications\n\nExclusion Criteria:\n\n* 1\\) Primary tumors of the spine or multiple tumors of the body, with\\>3 metastatic organs and\\>5 metastatic sites.\n* 2\\) Previously underwent spinal surgery, or received radiotherapy for the responsible segment of this treatment.\n* 3\\) Severe heart, lung, liver, kidney or other diseases affecting the surgery.\n* 4\\) Having cognitive impairment, sensory aphasia, and inability to understand basic instructions.\n* 5\\) Participated in clinical trials of other drugs or medical devices within 3 months prior to enrollment.\n* 6\\) Infectious diseases.\n* 7\\) Refuse to follow up or participate.\n* 8\\) The researchers determine that the patients are not suitable for enrollment this clinical trail.",true,"ALL","18 Years","75 Years",{"count":89,"type":90},182,"ESTIMATED","2 Years","OBSERVATIONAL","The purpose of this clinical trial is to explore the impact of En bloc surgery and separation surgery combined with radiation therapy on the prognosis and survival of patients with spinal oligometastatic cancer, describe the clinical results, and optimize future treatment goals",[95,96,97,98,99],"Spinal Metastases","Spinal Tumor","Radiotherapy","Malignant Bone Tumor","Surgery",[101,102],"Total enbloc spondylectomy","Oligometastases","2023-11-09",{"date":105,"type":106},"2023-11-13","ACTUAL",{"date":108,"type":106},"2023-07-01",{"date":110,"type":90},"2027-07-01",{"name":5,"class":6},1]