[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608977":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":10,"locations":10,"responsibleParty":12,"collaborators":10,"id":16,"slug":17,"hasResults":18,"nctId":19,"briefTitle":20,"officialTitle":21,"acronym":10,"eligibilityCriteria":22,"healthyVolunteers":18,"sex":23,"minAge":24,"maxAge":25,"enrollmentInfo":26,"targetDuration":10,"studyType":29,"phases":10,"briefSummary":30,"conditions":31,"keywords":33,"overallStatus":35,"whyStopped":10,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":10},{"fullName":5,"class":6},"Assiut University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Pediatric Wilson's Disease Group",null,"All eligible children with Wilson's disease (diagnosed and under treatment or newly diagnosed) evaluated cross-sectionally for endocrine function.",{"type":13,"investigatorFullName":14,"investigatorTitle":15,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Alaa Atef Ahmed Sayed","resident at the Pediatrics Department, Hepatology Unit, Assiut University Children's Hospital","100608977","endocrine-dysfunction-in-pediatric-wilsons-disease-100608977",false,"NCT07208565","Endocrine Dysfunction in Pediatric Wilson's Disease","A Cross-sectional Study of Endocrine Changes in Children With Wilson's Disease at Assiut University Children's Hospital","Inclusion Criteria:\n\n* Children aged 3-18 years\n\nConfirmed diagnosis of Wilson's disease (based on clinical features, biochemical markers such as serum ceruloplasmin and 24-hour urinary copper)\n\nBoth newly diagnosed and treated patients (chelation\u002Fzinc therapy)\n\nInformed consent from parents or guardians\n\nExclusion Criteria:\n\n* Congenital or acquired endocrine disorders unrelated to WD (e.g., congenital hypothyroidism, pituitary tumors)\n\nConcurrent use of medications affecting hormonal function unless prescribed for WD (steroids, thyroid replacements, contraceptives)\n\nChronic systemic illnesses that confound endocrine assessment (e.g., malignancy, chronic renal failure)","ALL","3 Years","18 Years",{"count":27,"type":28},30,"ESTIMATED","OBSERVATIONAL","This cross-sectional study investigates endocrine changes in children diagnosed with Wilson's disease, aiming to characterize hormonal dysfunctions affecting pituitary, thyroid, adrenal, and gonadal axes.",[32],"Wilson's Disease",[34],"Wilson's","NOT_YET_RECRUITING","2025-09-28",{"date":38,"type":39},"2025-10-06","ACTUAL",{"date":41,"type":28},"2026-06-30",{"date":43,"type":28},"2027-12-30",{"name":5,"class":6}]