[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100634822":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":21,"responsibleParty":44,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":48,"sex":54,"minAge":55,"maxAge":10,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":67,"overallStatus":24,"whyStopped":10,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":86},{"fullName":5,"class":6},"Exact Sciences Corporation","INDUSTRY",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Cohort 1",null,"Participants undergoing clinical evaluation for AUB",{"label":13,"type":10,"description":14,"interventionNames":10},"Cohort 2","Participants diagnosed with EC or AEH\u002FEIN",[16],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Sr. Clinical Trial Manager","CONTACT","608-982-1588","ENVISION_Study_Info@exactsciences.com",[22],{"facility":23,"status":24,"city":25,"state":26,"zip":27,"country":28,"countryCode":29,"cosmosGeoPoint":30,"geoPoint":35,"contacts":36},"Murfreesboro Medical Clinic","RECRUITING","Murfreesboro","Tennessee","37130","United States","US",{"type":31,"coordinates":32},"Point",[33,34],-86.39027,35.84562,{"lat":34,"lon":33},[37,41],{"name":38,"role":18,"phone":39,"phoneExt":10,"email":40},"Miles Guy","615-410-3460","mguy@icresearch.net",{"name":42,"role":43,"phone":10,"phoneExt":10,"email":10},"Brad Chesney, MD","PRINCIPAL_INVESTIGATOR",{"type":45,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100634822","endometrial-cancer-vaginal-fluid-specimen-collection-study-100634822",false,"NCT07544680","Endometrial Cancer Vaginal Fluid Specimen Collection Study","Endometrial Cancer Vaginal Fluid Specimen Collection Study: \"ENVISION\"","ENVISION","Inclusion Criteria\n\nCohort 1 Participants:\n\n* Age ≥ 45 years, OR age ≥ 18 years with at least one risk factor\n* Diagnosed with abnormal uterine bleeding (AUB)\n* Planning standard-of-care endometrial tissue sampling to assess for endometrial cancer (EC) or atypical endometrial hyperplasia\u002Fendometrial intraepithelial neoplasia (AEH\u002FEIN)\n\nCohort 2 Participants:\n\n* Age ≥ 18 years\n* Newly diagnosed, biopsy-confirmed EC or AEH\u002FEIN\n* Planning initial management for their endometrial pathology\n\nExclusion Criteria\n\n* Prior partial or complete hysterectomy\n* Current pregnancy\n* Prior pelvic or vaginal radiotherapy\n* Chemotherapy within past 5 years (except tamoxifen)\n* Any condition judged by the Investigator to preclude participation\n\nAdditional for Cohort 1:\n\n* Cancer diagnosis within past 5 years (except non-gynecologic skin cancer)\n* Current biopsy-proven cervical, vaginal, or vulvar cancer, or lower genital tract dysplasia\n* Current biopsy-proven endometrial cancer, hyperplasia, or benign polyp\n* Benign endometrial biopsy within last month\n\nAdditional for Cohort 2:\n\n* Cancer diagnosis other than EC within past 5 years (except non-gynecologic skin cancer)\n* Prior cervical cancer or biopsy-proven cervical dysplasia\n* Surgery for recurrent EC\n* Preoperative neoadjuvant chemotherapy or radiotherapy for current EC\n* Prior treatment or surgery to remove target pathology during current episode","FEMALE","18 Years",{"count":57,"type":58},4200,"ESTIMATED","OBSERVATIONAL","This is a multicenter, prospective, specimen collection study for development and evaluation of tests used to detect endometrial cancer, other cancers, or their causes.",[62,63,64,65,66],"Abnormal Uterine Bleeding (AUB)","Endometrial Cancer","Atypical Endometrial Hyperplasia","Endometrial Hyperplasia With Atypia","Endometrial Intraepithelial Neoplasia",[62,68,69,70,71,72,73,74,75,76],"Endometrial Cancer (EC)","Atypical Endometrial Hyperplasia (AEH)","Endometrial Hyperplasia with Atypia","Endometrial Intraepithelial Neoplasia (EIN)","Precancerous Conditions","Post-Menopausal Bleeding","Specimen Collection","Sample Collection","in vitro diagnostic (IVD) devices","2026-04-15",{"date":79,"type":80},"2026-04-22","ACTUAL",{"date":82,"type":80},"2026-03-10",{"date":84,"type":58},"2028-04-24",{"name":5,"class":6},1]