[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100499109":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":13,"centralContacts":18,"locations":24,"responsibleParty":63,"collaborators":66,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":7,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":7,"enrollmentInfo":79,"targetDuration":7,"studyType":82,"phases":7,"briefSummary":83,"conditions":84,"keywords":89,"overallStatus":27,"whyStopped":7,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":102},{"fullName":5,"class":6},"University of Chile","OTHER",null,[9],{"type":10,"name":11,"description":12,"armGroupLabels":7,"otherNames":7},"DIAGNOSTIC_TEST","FMD - Troponin measurement","Echographic FMD evaluation. Pre and post-operative troponin measurements.",[14],{"name":15,"affiliation":16,"role":17},"Felipe Maldonado||, M.D.,M.Sc.","Hospital Clinico de la Universidad de Chile","STUDY_CHAIR",[19],{"name":20,"role":21,"phone":22,"phoneExt":7,"email":23},"Felipe Maldonado, M.D., M.Sc.","CONTACT","+56 2 2978 8221","fmaldonado@uchile.cl",[25],{"facility":26,"status":27,"city":28,"state":29,"zip":30,"country":31,"countryCode":32,"cosmosGeoPoint":33,"geoPoint":38,"contacts":39},"Hospital Clínico de la Universidad de Chile","RECRUITING","Independencia","Santiago Metropolitan","8380456","Chile","CL",{"type":34,"coordinates":35},"Point",[36,37],-70.66647,-33.41167,{"lat":37,"lon":36},[40,41,43,46,48,50,51,53,55,57,59,61],{"name":20,"role":21,"phone":7,"phoneExt":7,"email":7},{"name":42,"role":21,"phone":7,"phoneExt":7,"email":7},"Roberto González, M.D.",{"name":44,"role":45,"phone":7,"phoneExt":7,"email":7},"Mónica Cáceres, Ph.D.","PRINCIPAL_INVESTIGATOR",{"name":47,"role":45,"phone":7,"phoneExt":7,"email":7},"Oscar Cerda, Ph.D.",{"name":49,"role":45,"phone":7,"phoneExt":7,"email":7},"Catalina Díaz-Papapietro, M.D.",{"name":42,"role":45,"phone":7,"phoneExt":7,"email":7},{"name":52,"role":45,"phone":7,"phoneExt":7,"email":7},"Diego Varela, Ph.D.",{"name":54,"role":45,"phone":7,"phoneExt":7,"email":7},"Felipe Medina, Ph.D.",{"name":56,"role":45,"phone":7,"phoneExt":7,"email":7},"Sergio Bustamante, M.D.",{"name":58,"role":45,"phone":7,"phoneExt":7,"email":7},"José I Egaña, M.D., Ph.D.",{"name":60,"role":45,"phone":7,"phoneExt":7,"email":7},"Marcelo Llancaqueo, M.D.",{"name":62,"role":45,"phone":7,"phoneExt":7,"email":7},"Alfredo Parra, M.D., Ph.D.",{"type":45,"investigatorFullName":64,"investigatorTitle":65,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"Felipe Andrés Maldonado Caniulao","Principal Investigator",[67],{"name":68,"class":6},"Agencia Nacional de Investigación y Desarrollo","100499109","endothelial-dysfunction-and-non-cardiac-surgery-100499109",false,"NCT05778981","Endothelial Dysfunction and Non-cardiac Surgery","Endothelial Dysfunction During Non-cardiac Surgery and Major Clinical Events","Inclusion Criteria:\n\n* Signed informed consent\n* Patients 45 years or older\n\nExclusion Criteria:\n\n* Refuse to participate in the study\n* Myocardial injury or acute myocardial infarction less than two weeks ago\n* Patients who expect less than 2 days of hospitalization\n* Patients in whom the troponin elevation is attributed to a secondary cause (for example, sepsis, pulmonary thromboembolism, electrical cardioversion, etc.)\n* Use of chemotherapy less than 2 weeks ago",true,"ALL","45 Years",{"count":80,"type":81},200,"ESTIMATED","OBSERVATIONAL","Endothelial dysfunction is a cardiovascular disease hallmark. After non-cardiac surgery, cardiovascular events correlate with surgical outcomes. Understanding the role of endothelial function in these events is crucial.\n\nThis research aims to study endothelial function and its association with cardiovascular events.",[85,86,87,88],"Surgery","Cardiac Death","Stroke","Myocardial Injury",[90,91,92],"FMD","Flow-Mediated Dilatation","Troponin","2024-12-05",{"date":95,"type":96},"2024-12-10","ACTUAL",{"date":98,"type":96},"2023-03-25",{"date":100,"type":81},"2025-12-01",{"name":5,"class":6},1]