[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100465800":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":57,"collaborators":25,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":65,"eligibilityCriteria":66,"healthyVolunteers":62,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":25,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":25,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":84,"leadSponsor":86,"locationsCount":87},{"fullName":5,"class":6},"Zhongda Hospital","OTHER",[8,13],{"label":9,"type":6,"description":10,"interventionNames":11},"The control group","Treating with balloon dilation or stent implantation only,",[12],"Device: PTA",{"label":14,"type":15,"description":16,"interventionNames":17},"The EDN group","EXPERIMENTAL","Treating with EDN at the site of the iliac artery distal to the superficial femoral artery proximal before balloon dilation or stent implantation.",[18],"Device: endovascular denervation",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","endovascular denervation","Treating with EDN at the site of the iliac artery distal to the superficial femoral artery proximal before balloon dilation or stent implantation",[14],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"PTA","Treating with balloon dilation or stent implantation",[9],[31],{"name":32,"affiliation":5,"role":33},"Gao-Jun Teng, MD","PRINCIPAL_INVESTIGATOR",[35,39],{"name":32,"role":36,"phone":37,"phoneExt":25,"email":38},"CONTACT","+86 25 83272121","gjteng@seu.edu.cn",{"name":40,"role":36,"phone":41,"phoneExt":25,"email":42},"Guo-Feng Zhao, MD","+86-15951804797","dreamboyseu@163.com",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":25,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":25},"Zhongda Hospital, Southeast University","RECRUITING","Nanjing","Jiangsu","China","CN",{"type":52,"coordinates":53},"Point",[54,55],118.77778,32.06167,{"lat":55,"lon":54},{"type":33,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Gao-jun Teng","Clinical Professor","100465800","endovascular-denervation-for-the-treatment-of-patients-with-peripheral-arterial-disease-100465800",false,"NCT05345431","Endovascular Denervation for the Treatment of Patients With Peripheral Arterial Disease","EDPAD","Inclusion Criteria:\n\n1. eligible subjects aged 18-75 years,\n2. clinically confirmed PAD patients in Rutherford category II-VI.\n\nExclusion Criteria:\n\n1. thrombolytic therapy performed within 30 days,\n2. patients who had undergone vascular bypass surgery before this study,\n3. allergy or contraindication of antiplatelet drugs, anticoagulants, thrombolytic drugs and contrast agents,\n4. patients with obvious bleeding tendency, coagulation dysfunction, hypercoagulability and blood system diseases,\n5. serious liver and kidney diseases,\n6. history of hemorrhagic stroke within the last 1 month or ischemic stroke or transient ischemic attack within 2 weeks,\n7. pacemaker implants,\n8. patients who are pregnant, breast-feeding or planning pregnancy,\n9. expected survival \\\u003C 24 months.","ALL","18 Years","75 Years",{"count":71,"type":72},54,"ESTIMATED","INTERVENTIONAL",[75],"NA","Sympathetic overactivity partly promotes the development of peripheral artery disease which mainly leads to ischemia of the lower limbs. Endovascular arterial denervation (ED) is a minimally invasive technique which could deliver Radiofrequency energy by a multi-electrode catheter to the Lower limb artery to restore Sympathetic activity. The purpose of this study is to evaluate the effects of multi-electrode radiofrequency ablation system on lower limb ischemia with PAD.",[78],"PAD","2022-04-20",{"date":81,"type":82},"2022-04-25","ACTUAL",{"date":81,"type":72},{"date":85,"type":72},"2026-06-30",{"name":5,"class":6},1]