[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100546632":3},{"organization":4,"armGroups":7,"interventions":29,"overallOfficials":40,"centralContacts":46,"locations":55,"responsibleParty":73,"collaborators":75,"id":79,"slug":80,"hasResults":81,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":35,"eligibilityCriteria":85,"healthyVolunteers":86,"sex":87,"minAge":88,"maxAge":89,"enrollmentInfo":90,"targetDuration":35,"studyType":93,"phases":94,"briefSummary":96,"conditions":97,"keywords":101,"overallStatus":58,"whyStopped":35,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},{"fullName":5,"class":6},"University of California, San Francisco","OTHER",[8,14,17,20,23],{"label":9,"type":10,"description":11,"interventionNames":12},"MediTrain 30m\u002Fday for 6wks","EXPERIMENTAL","Participants will engage with a digital meditation app for the time listed above.",[13],"Device: MediTrain",{"label":15,"type":10,"description":11,"interventionNames":16},"MediTrain 15m\u002Fday for 6wks",[13],{"label":18,"type":10,"description":11,"interventionNames":19},"MediTrain 30m\u002Fday for 3wks",[13],{"label":21,"type":10,"description":11,"interventionNames":22},"MediTrain 15m\u002Fday for 3wks",[13],{"label":24,"type":25,"description":26,"interventionNames":27},"Active Control Group","ACTIVE_COMPARATOR","An active control application will be used for this arm. The total training experience here will be for 6 weeks (5 days\u002Fweek), with each training session lasting \\~30 minutes (not including self-paced breaks). Here an app that is matched in terms of expectancy of benefits compared to our training groups will be determined by questioning 100 naïve individuals to predict their expected improvement on each cognitive domain across a multitude of possible applications.",[28],"Device: Worder",[30,36],{"type":31,"name":32,"description":33,"armGroupLabels":34,"otherNames":35},"DEVICE","MediTrain","MediTrain is a tablet-based, meditation-inspired, cognitive training game aimed at improving self-regulation of internal attention and distractions. It was developed in collaboration with meditation thought-leader Jack Kornfield, and Zynga, a world-class video game company. It was created to make benefits of concentrative meditation more easily accessible to anyone, including complete novices. This is achieved by creating a game that yields quantifiable and attainable goals, provides feedback, and includes an adaptive algorithm to gradually increase difficulty as users improve.",[21,15,18,9],null,{"type":31,"name":37,"description":38,"armGroupLabels":39,"otherNames":35},"Worder","Worder was designed to enhance visual motor and visual spatial skills in individuals of all ages and cognitive abilities. Visual processing is required for all cognitive abilities that involve vision including attention, working memory, and task management. Worder's goal is to improve cognitive function more broadly by developing this critical skill underlying multiple abilities.",[24],[41,44],{"name":42,"affiliation":5,"role":43},"Adam Gazzaley, MD\u002FPhD","PRINCIPAL_INVESTIGATOR",{"name":45,"affiliation":5,"role":43},"David Ziegler, PhD",[47,51],{"name":45,"role":48,"phone":49,"phoneExt":35,"email":50},"CONTACT","4154762164","david.ziegler@ucsf.edu",{"name":52,"role":48,"phone":53,"phoneExt":35,"email":54},"Monique de Villa, MS, MPH","209-233-3878","meditrain@ucsf.edu",[56],{"facility":57,"status":58,"city":59,"state":60,"zip":61,"country":62,"countryCode":63,"cosmosGeoPoint":64,"geoPoint":69,"contacts":70},"University of California San Francisco","RECRUITING","San Francisco","California","94158","United States","US",{"type":65,"coordinates":66},"Point",[67,68],-122.41942,37.77493,{"lat":68,"lon":67},[71],{"name":45,"role":48,"phone":72,"phoneExt":35,"email":50},"415-476-2164",{"type":74,"investigatorFullName":35,"investigatorTitle":35,"investigatorAffiliation":35,"oldNameTitle":35,"oldOrganization":35},"SPONSOR",[76],{"name":77,"class":78},"National Institute on Aging (NIA)","NIH","100546632","enhancing-attention-and-wellbeing-using-digital-therapeutics-100546632",false,"NCT06397469","Enhancing Attention and Wellbeing Using Digital Therapeutics","Optimizing a Closed-loop Digital Meditation Intervention for Remediating Cognitive Decline and Reducing Stress in Older Adults","Inclusion Criteria:\n\n* 60+ years old (adult)\n* English language fluency\n* owning a smartphone or tablet\n\nExclusion Criteria:\n\n* Under 60 years old (minor)",true,"ALL","60 Years","99 Years",{"count":91,"type":92},4000,"ESTIMATED","INTERVENTIONAL",[95],"NA","The goals of the proposed research are to first determine the minimal and\u002For optimal dose of a digital intervention required for cognitive enhancement, and then to examine the impact of several potential moderators of treatment effects (i.e., cognitive decline, AD polygenic hazard score, cardiovascular risk, and race\u002Fethnicity). This knowledge gained from his high-impact study with transform the field of cognitive interventions, paving the way for a precision medicine model for cognitive enhancing interventions that improve quality of life for older adults and individuals with cognitive deficits at risk of developing dementia.",[98,99,100],"Aging","MCI","Cognitive Decline",[102,103,104,105,106,107,108,109,110,111,112],"healthy aging","attention","cognition","dementia","intervention","digital","behavioral","prevention","decline","stress reduction","Quality of life","2026-02-20",{"date":115,"type":116},"2026-02-24","ACTUAL",{"date":118,"type":116},"2024-04-01",{"date":120,"type":92},"2029-06",{"name":5,"class":6},1]