[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100497584":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":29,"locations":34,"responsibleParty":54,"collaborators":56,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":64,"acronym":24,"eligibilityCriteria":65,"healthyVolunteers":66,"sex":67,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":24,"studyType":73,"phases":74,"briefSummary":76,"conditions":77,"keywords":80,"overallStatus":37,"whyStopped":24,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":95},{"fullName":5,"class":6},"Dana-Farber Cancer Institute","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Nest Refinement Phase","EXPERIMENTAL","20 participants and clinicians will complete study procedures as outlined:\n\n* Nest portal orientation and access.\n* Semi-structured, 30-minute interviews. Solicited feedback on content and processes will refine the intervention for a pilot phase.",[13],"Behavioral: Nest Platform",{"label":15,"type":10,"description":16,"interventionNames":17},"Nest Pilot Phase","10 Participants and 10 clinicians will complete study procedures as outlined:\n\n* Baseline survey (participant).\n* Standard clinic visit.\n* Nest portal orientation and access (participant and clinician).\n* Post-visit survey (participant and clinician).\n* Brief, 30-minute, semi-structured interview (participant and clinician).",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","Nest Platform","Patient- and clinician-facing portal via secure link",[15,9],null,[26],{"name":27,"affiliation":5,"role":28},"Jennifer Mack, MD","PRINCIPAL_INVESTIGATOR",[30],{"name":27,"role":31,"phone":32,"phoneExt":24,"email":33},"CONTACT","617-632-6818","Jennifer_mack@dfci.harvard.edu",[35],{"facility":36,"status":37,"city":38,"state":39,"zip":40,"country":41,"countryCode":42,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Dana Farber Cancer Institute","RECRUITING","Boston","Massachusetts","02115","United States","US",{"type":44,"coordinates":45},"Point",[46,47],-71.05977,42.35843,{"lat":47,"lon":46},[50,53],{"name":27,"role":31,"phone":51,"phoneExt":24,"email":52},"(617) 632-6622","JMACK@PARTNERS.ORG",{"name":27,"role":28,"phone":24,"phoneExt":24,"email":24},{"type":28,"investigatorFullName":27,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":24,"oldOrganization":24},"Principal Investigator",[57],{"name":58,"class":59},"Nest Genomics","INDUSTRY","100497584","enhancing-information-management-for-young-adults-after-genetic-cancer-risk-testing-100497584",false,"NCT05759143","Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing","Inclusion Criteria AIM 1:\n\n* YA Patients:\n\n  * Ages 18-39 years, inclusive.\n  * Has had previous cancer genetic testing, with a finding of a pathogenic variant or VUS; patient has previously received results from the clinical team.\n  * English-speaking and -reading.\n  * Receiving care at DFCI.\n  * Not undergoing active cancer therapy at the time of approach.\n* Clinicians:\n\n  * Cancer risk physicians (oncologists, gastroenterologists, geneticists), oncologists, nurse practitioners, physician assistants, or genetic counselors.\n  * English-speaking and -reading.\n  * Cares for YAs aged 18-39 with cancer risk syndromes.\n\nInclusion Criteria AIM 2:\n\n* YA Patients:\n\n  * Ages 18-39 years, inclusive.\n  * Has had previous cancer genetic testing, with a finding of a pathogenic variant or VUS; patient has previously received results from the clinical team.\n  * English-speaking and -reading.\n  * Receiving care at Dana-Farber Cancer Institute.\n  * Did not participate in a stakeholder interview (Aim 1).\n  * Not undergoing active cancer therapy at the time of approach.\n* Clinicians:\n\n  * Oncologists, nurse practitioners, cancer risk physicians, or genetic counselors.\n  * English-speaking and -reading.\n  * Caring for a participating YA.",true,"ALL","18 Years","39 Years",{"count":71,"type":72},40,"ESTIMATED","INTERVENTIONAL",[75],"NA","This research is being done to develop the electronic platform Nest for young adults (ages 18-39) who have had prior cancer genetic testing. The platform will give patients and their clinicians access to continuously updated information about both pathogenic variants and variants of uncertain significance (VUS).\n\nThe name of the intervention used in this research study is:\n\nNest portal (electronic platform for patients and clinicians)",[78,79],"Genetic Predisposition to Disease","Genetic Predisposition",[78,79,81,82,83,84,85],"Genetic Testing","Cancer Risk Syndromes","VUS","Variant of Uncertain Significance","Pathogenic Variant","2026-04-21",{"date":88,"type":89},"2026-04-24","ACTUAL",{"date":91,"type":89},"2023-05-01",{"date":93,"type":72},"2026-07-30",{"name":5,"class":6},1]