[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100565172":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":25,"centralContacts":29,"locations":38,"responsibleParty":59,"collaborators":61,"id":65,"slug":66,"hasResults":67,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":24,"eligibilityCriteria":71,"healthyVolunteers":67,"sex":72,"minAge":73,"maxAge":24,"enrollmentInfo":74,"targetDuration":24,"studyType":77,"phases":78,"briefSummary":80,"conditions":81,"keywords":83,"overallStatus":40,"whyStopped":24,"lastUpdateSubmitDate":91,"lastUpdatePostDateStruct":92,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":100},{"fullName":5,"class":6},"University of Nevada, Las Vegas","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Amputee peers","EXPERIMENTAL","This research uses a cross-over design to expose the participants with lower limb loss to the two training conditions (observing amputee peers vs. non-amputees) in random order, with a 4-week washout period between conditions. In this arm, participants are instructed to learn from video demonstrations by amputee peers. The videos will show balance and fall recovery movement tasks performed by the models, 15-30 seconds in length. The instruction to the participants is: \"Please watch and learn the tasks as performed by the demonstrator. You (the participant) will be asked to perform these tasks later.\"",[13],"Behavioral: Balance and fall recovery training",{"label":15,"type":10,"description":16,"interventionNames":17},"Non-amputees","In this arm, participants with lower limb loss are instructed to learn from video demonstrations by non-amputees. The videos will show balance and fall recovery movement tasks performed by the models, 15-30 seconds in length. The instruction to the participants is: \"Please watch and learn the tasks as performed by the demonstrator. You (the participant) will be asked to perform these tasks later.\"",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":24},"BEHAVIORAL","Balance and fall recovery training","Following the video observation described in the arms, participants will undergo training to physically practice the motor tasks. The training will take place over a 2-week period encompassing 40 practice trials for each task over the training sessions. During training, the investigators will continuously monitor the changes in balance and fall recovery task performance, and will provide feedback. Participants can request to re-watch the demonstration video that they were assigned to at any time.",[9,15],null,[26],{"name":27,"affiliation":5,"role":28},"Szu-Ping Lee, PhD","PRINCIPAL_INVESTIGATOR",[30,34],{"name":27,"role":31,"phone":32,"phoneExt":24,"email":33},"CONTACT","702-895-3086","szu-ping.lee@unlv.edu",{"name":35,"role":31,"phone":36,"phoneExt":24,"email":37},"Joel Snyder, PhD","7028954692","joel.snyder@unlv.edu",[39],{"facility":5,"status":40,"city":41,"state":42,"zip":43,"country":44,"countryCode":45,"cosmosGeoPoint":46,"geoPoint":51,"contacts":52},"RECRUITING","Las Vegas","Nevada","89154","United States","US",{"type":47,"coordinates":48},"Point",[49,50],-115.13722,36.17497,{"lat":50,"lon":49},[53,55],{"name":27,"role":31,"phone":54,"phoneExt":24,"email":33},"7028953086",{"name":56,"role":31,"phone":57,"phoneExt":24,"email":58},"Fu-Lien Wu, PhD","2132758254","fu-lien.wu@unlv.edu",{"type":60,"investigatorFullName":24,"investigatorTitle":24,"investigatorAffiliation":24,"oldNameTitle":24,"oldOrganization":24},"SPONSOR",[62],{"name":63,"class":64},"United States Department of Defense","FED","100565172","enhancing-motor-function-in-individuals-with-lower-limb-amputation-100565172",false,"NCT06638723","Enhancing Motor Function in Individuals with Lower Limb Amputation","Enhancing Motor Function in Individuals with Lower Limb Amputation Through Peer-Based Balance and Fall Recovery Skill Training","Inclusion Criteria:\n\n* 1\\) have unilateral lower limb amputation,\n* 2\\) age \\>18 years,\n* 3\\) are properly fitted with a walking prosthesis and use it regularly with at least moderate proficiency (K-2 level or above, further defined as scoring greater than 50 percentile on the Prosthetic Limb Users Survey of Mobility),\n* 4\\) able to stand for at least 5 minutes without using an assistive device or experiencing excessive fatigue,\n* 5\\) willing to travel to UNLV 6 times for training and testing.\n\nExclusion Criteria:\n\n* 1\\) have other concurrent central nervous system diseases that influence motor function and balance,\n* 2\\) have leg\u002Ffoot ulcer or other conditions that cause pain during weight-bearing,\n* 3\\) have cardiovascular, respiratory or other critical health conditions that preclude moderate physical activity.","ALL","18 Years",{"count":75,"type":76},20,"ESTIMATED","INTERVENTIONAL",[79],"NA","The overall goal of this research project is to investigate the effectiveness and the science of peer-based prosthetic skill training in individuals with leg amputation. Our belief is that amputee learners will show improved skill learning when observing demonstrations from other amputees, as opposed to observing nonamputee models. The investigators will accomplish the objective by answering the following two questions:\n\nQuestion 1: Does peer-based observation training works better for learning motor tasks for individuals with lower limb amputation (LLA)?\n\nQuestion 2: Are there differences in visual focus, behavior, and brain activation patterns when observing motor task demonstrations from amputee peers vs. non-amputees?\n\nParticipants of this study will be asked to learn a balance and a fall recovery task by observing video demonstrations by amputee peers vs. non-amputees. The investigators will compare which setting produce better learning.",[82],"Amputation",[84,85,86,87,88,89,90],"limb loss","peer support","motor learning","EEG","falls","balance","prosthetics","2024-10-10",{"date":93,"type":94},"2024-10-15","ACTUAL",{"date":96,"type":94},"2023-06-30",{"date":98,"type":76},"2025-12-31",{"name":5,"class":6},1]