[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100624544":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":30,"locations":36,"responsibleParty":46,"collaborators":25,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":25,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":25,"enrollmentInfo":58,"targetDuration":25,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":70,"overallStatus":75,"whyStopped":25,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},{"fullName":5,"class":6},"Samsung Medical Center","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Enteral Nutrition (EN) Group","EXPERIMENTAL","In the enteral nutrition group, enteral nutrition is initiated during the early recovery phase of shock in critically ill adult patients. Nutrition is provided while patients are receiving decreasing doses of vasopressors in the intensive care unit, according to standard institutional protocols.",[13],"Other: enteral nutrition",{"label":15,"type":16,"description":17,"interventionNames":18},"Parenteral Nutrition (PN) Group","ACTIVE_COMPARATOR","In the parenteral nutrition group, parenteral nutrition is administered during the early recovery phase of shock in critically ill adult patients. Nutrition is provided while patients are receiving decreasing doses of vasopressors in the intensive care unit, according to standard institutional protocols.",[19],"Other: Parenteral Nutrition",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"enteral nutrition","Patients will be randomized in a 1:1 ratio to receive either enteral nutrition or parenteral nutrition. Participants assigned to this group will receive enteral nutrition during the early recovery phase of shock while receiving decreasing vasopressor support in the intensive care unit.",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Parenteral Nutrition","Patients will be randomized in a 1:1 ratio to receive either enteral nutrition or parenteral nutrition. Participants assigned to this group will receive parenteral nutrition during the early recovery phase of shock while receiving decreasing vasopressor support in the intensive care unit.",[15],[31],{"name":32,"role":33,"phone":34,"phoneExt":25,"email":35},"Jeong Hoon Yang","CONTACT","82-2-3410-3419","jhysmc@gmail.com",[37],{"facility":5,"status":25,"city":38,"state":25,"zip":25,"country":39,"countryCode":25,"cosmosGeoPoint":40,"geoPoint":45,"contacts":25},"Seoul","South Korea",{"type":41,"coordinates":42},"Point",[43,44],126.9784,37.566,{"lat":44,"lon":43},{"type":47,"investigatorFullName":32,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Professor","100624544","enteral-versus-parenteral-nutrition-during-recovery-after-shock-100624544",false,"NCT07411014","Enteral Versus Parenteral Nutrition During Recovery After Shock","Enteral Versus Parenteral Nutrition During Early Recovery in the Critically Ill After Shock: A Prospective, Multicenter, Open-label, Randomized Controlled Study","Screening Criteria:\n\n* Subjects must be at least 19 years of age at the time of screening.\n* Subjects must be admitted to the intensive care unit (ICU).\n* Subjects must be receiving vasopressor therapy for shock.\n* Subjects must have a documented history of maximum vasopressor requirement with a vasopressor-inotropic score (VIS) of 12 or greater, calculated as follows:\n\nVIS = dopamine dose (µg\u002Fkg\u002Fmin) + dobutamine dose (µg\u002Fkg\u002Fmin) + 10 × milrinone dose (µg\u002Fkg\u002Fmin) + 100 × epinephrine dose (µg\u002Fkg\u002Fmin) + 100 × norepinephrine dose (µg\u002Fkg\u002Fmin) + 10,000 × vasopressin dose (U\u002Fkg\u002Fmin)\n\nInclusion Criteria:\n\n* Subjects must meet all screening criteria.\n* Subjects must have central venous access suitable for the administration of parenteral nutrition (PN).\n* Subjects must demonstrate a decreasing vasopressor requirement, defined as a current VIS of 12 or less at the time of enrollment.\n\nExclusion Criteria:\n\n* Subjects with contraindications to enteral nutrition (EN) or parenteral nutrition (PN) at the time of enrollment will be excluded.\n* Subjects requiring specific nutritional management, including but not limited to long-term home enteral nutrition, long-term parenteral nutrition, or a diagnosis of refeeding syndrome, will be excluded.\n* Subjects who are pregnant or breastfeeding will be excluded.\n* Subjects with severe comorbid conditions associated with an estimated life expectancy of less than three months will be excluded.\n* Subjects with a documented do-not-resuscitate (DNR) order will be excluded.\n* Subjects with active gastrointestinal bleeding will be excluded.\n* Subjects who have undergone gastrointestinal surgery within one month prior to enrollment will be excluded.\n* Subjects currently participating in another randomized controlled trial comparing enteral nutrition and parenteral nutrition will be excluded.","ALL","19 Years",{"count":59,"type":60},1150,"ESTIMATED","INTERVENTIONAL",[63],"NA","This study compares enteral nutrition and parenteral nutrition in critically ill adult patients recovering from shock while receiving decreasing doses of vasopressors in the intensive care unit.\n\nEligible patients will be randomly assigned to receive either enteral or parenteral nutrition during the early recovery phase of shock.\n\nThe study aims to determine whether enteral nutrition improves clinical outcomes, including ICU mortality and ICU-acquired infections, compared with parenteral nutrition.",[66,67,68,69],"Shock","Critical Illness","Nutritional Support","Vasopressor Therapy",[71,27,72,73,74,66],"Enteral Nutrition","Critically Ill Patients","Shock Recovery","Vasopressor Weaning","NOT_YET_RECRUITING","2026-02-13",{"date":78,"type":79},"2026-02-18","ACTUAL",{"date":81,"type":60},"2026-02-01",{"date":83,"type":60},"2029-12-31",{"name":5,"class":6},1]