[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100569158":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":22,"responsibleParty":46,"collaborators":10,"id":49,"slug":50,"hasResults":51,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":10,"eligibilityCriteria":55,"healthyVolunteers":51,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":62,"studyType":63,"phases":10,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Shanghai University of Traditional Chinese Medicine","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"external validation cohort",null,"The external validation cohort was composed of primary EOCRC patients who underwent radical resection at Putuo Hospital and Yueyang Hospital, both affiliated with Shanghai University of Traditional Chinese Medicine. The cohort includes patients diagnosed between January 2014 and June 2024.\n\nInclusion criteria: Patients with pathologically confirmed primary EOCRC, aged under 50 years, and who received radical surgery (stages I-III according to the AJCC 7th edition).\n\nExclusion criteria: Patients with multiple primary cancers, survival time under 1 month, or missing critical data.",[13],{"name":14,"affiliation":15,"role":16},"Wanli Deng","Putuo Hospital, Shanghai University of Traditional Chinese Medicine","PRINCIPAL_INVESTIGATOR",[18],{"name":14,"role":19,"phone":20,"phoneExt":10,"email":21},"CONTACT","+86 13166062368","tcmdwl@163.com",[23,36],{"facility":15,"status":10,"city":24,"state":10,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":28,"geoPoint":33,"contacts":34},"Shanghai","200062","China","CN",{"type":29,"coordinates":30},"Point",[31,32],121.45806,31.22222,{"lat":32,"lon":31},[35],{"name":14,"role":19,"phone":10,"phoneExt":10,"email":10},{"facility":37,"status":10,"city":24,"state":10,"zip":25,"country":26,"countryCode":27,"cosmosGeoPoint":38,"geoPoint":40,"contacts":41},"Yueyang Hospital of Integrated Traditional Chinese and Western Medicine",{"type":29,"coordinates":39},[31,32],{"lat":32,"lon":31},[42],{"name":43,"role":19,"phone":44,"phoneExt":10,"email":45},"Yabin Gong","+86 18918923873","gongyabin@hotmail.com",{"type":16,"investigatorFullName":47,"investigatorTitle":48,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Wanli Deng, MD","Principal Investigator","100569158","eocrcpred-an-ai-model-to-predict-survival-in-eocrc-patients-after-surgery-100569158",false,"NCT06690606","EOCRCPred: an AI Model to Predict Survival in EOCRC Patients After Surgery","EOCRCPred: an AI Model for Predicting Overall Survival in Early-Onset Stage I-III Colorectal Cancer Patients Post-Radical Resection-A SEER Database and Dual-Center Chinese Medical Institutions Study","Inclusion Criteria:\n\n* Primary EOCRC confirmed by pathological histological examination (ICD-10 codes: C18.0, C18.2-18.9, C19.9, C20.9)\n* Radical surgery performed (Specific Surgery Codes 30-70, including partial\u002Fsubtotal colectomy, hemicolectomy, right\u002Fleft colectomy, and total colectomy, as well as partial or total removal of other organs and regional lymph nodes)\n* Stage I-III disease according to the 7th AJCC-TNM system\n\nExclusion Criteria:\n\n* Patients with multiple primary cancers or other malignancies\n* Survival time of less than 1 month, or absence of postoperative follow-up information\n* Incomplete critical clinical feature information","ALL","18 Years","49 Years",{"count":60,"type":61},250,"ESTIMATED","1 Month","OBSERVATIONAL","The goal of this observational study is to develop a predictive model for overall survival in patients under the age of 50 who have undergone surgery for early-onset colorectal cancer (EOCRC). The main question it aims to answer is:\n\nCan machine learning models accurately predict the long-term survival of EOCRC patients after surgical treatment?\n\nParticipants who have already undergone surgery for EOCRC as part of their regular medical care will have their clinical data analyzed, with survival outcomes tracked through follow-up assessments. An online survival calculator will also be developed to aid clinicians and patients in predicting personalized survival outcomes.",[66],"Colorectal Cancer",[68,69,70,71,72],"AI model","prediction","Early-Onset Colorectal Cancer (EOCRC)","postoperative survival","surgery","NOT_YET_RECRUITING","2024-11-13",{"date":76,"type":77},"2024-11-15","ACTUAL",{"date":79,"type":61},"2024-11-12",{"date":81,"type":61},"2025-05-11",{"name":5,"class":6},2]