[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100566524":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":25,"locations":37,"responsibleParty":55,"collaborators":25,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":25,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":25,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":79,"overallStatus":40,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":89,"leadSponsor":91,"locationsCount":92},{"fullName":5,"class":6},"Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital","OTHER",[8,15],{"label":9,"type":10,"description":11,"interventionNames":12},"Grup E (External Oblique Intercostal Plane Block)","ACTIVE_COMPARATOR","At the end of the surgical procedure,a high-frequency linear probe will be sterilely covered,and an 80mm block needle will be used for the procedure.Under sterile conditions,the ultrasound probe will be placed in a parasagittal position in the area between the anterior axillary line and the midclavicular line at the level of the 10th rib, and then slid cranially along the longitudinal axis to the level of the 6th and 7th ribs. After visualizing the external oblique muscle, the block needle will be inserted using an in-plane technique,and 5ml of saline will be administered to confirm the location at the external oblique intercostal plane between the external oblique muscle and the 6th rib. Once the location is confirmed, 20cc of 0.25%bupivacaine will be infiltrated into the EOIP. The same procedure will be applied to the opposite side (totally 40 ml).",[13,14],"Device: ultrasound guided external oblique intercostal plane block","Drug: paracetamol, tramadol, and ondansetron",{"label":16,"type":6,"description":17,"interventionNames":18},"Grup T ( Trocar entry site infiltration)","After the trocar removed during the surgical procedure, the surgeon will administer 5 ml of 0.25% bupivacaine infiltration to each trocar entry site.",[19,14],"Drug: Bupivacaine injection",[21,26,33],{"type":22,"name":23,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","ultrasound guided external oblique intercostal plane block",[9],null,{"type":27,"name":28,"description":29,"armGroupLabels":30,"otherNames":31},"DRUG","Bupivacaine injection","5 ml local anesthetic for each trocar sides",[16],[32],"Local anesthetic injection",{"type":27,"name":34,"description":35,"armGroupLabels":36,"otherNames":25},"paracetamol, tramadol, and ondansetron","As standard multimodal analgesia, 20 min before the end of the surgery patients will receive 1 g of paracetamol, 1-2 mg\u002Fkg of tramadol, and 4 mg of ondansetron via intravenous infusion.\n\nAll patients will be recovered in the PACU, and after confirming an Aldrete score of \\>9, a PCA (patient-controlled analgesia) device will be installed with morphine prepared at a dose appropriate for the patient's age. Patients will be administered paracetamol 1 gr IV every 8 hours in the postoperative period. When patients have a Numerical Rating Scale (NRS) score is ≥ 4, 1 mg\u002Fkg iv tramadol will be administered as a rescue analgesic",[9,16],[38],{"facility":39,"status":40,"city":41,"state":25,"zip":25,"country":42,"countryCode":25,"cosmosGeoPoint":43,"geoPoint":48,"contacts":49},"Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital","RECRUITING","Istanbul","Turkey (Türkiye)",{"type":44,"coordinates":45},"Point",[46,47],28.94966,41.01384,{"lat":47,"lon":46},[50],{"name":51,"role":52,"phone":53,"phoneExt":25,"email":54},"Mehmet Cihangir Ağca, Medical Doctor","CONTACT","+905367959178","mehmetcihangiragca@gmail.com",{"type":56,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100566524","eoib-for-laparoscopic-cholecystectomy-100566524",false,"NCT06656299","EOIB for Laparoscopic Cholecystectomy","Evaluation of Post-Operative Analgesic Efficacy of Bilateral External Oblique Intercostal Plane Block Versus Wound Site Infiltration Control Group in Patients Underwent Laparoscopic Cholecystectomy Surgery","Inclusion Criteria:\n\n* Patients aged 18 to 65 who will be scheduled for an elective laparoscopic cholecystectomy under general anesthesia\n* ASA (American Society of Anesthesiologists) I-II-III\n\nExclusion Criteria:\n\n* presence of coagulation disorder\n* infection at the injection site of the block\n* known allergy to local anesthetics\n* advanced hepatic, heart or renal failure\n* history of abdominal surgery or trauma\n* conversion of laparoscopic to open surgery\n* consumption of any pain killers within the 24 h before the operation\n* chronic opioid consumption\n* pregnancy\n* alcohol or drug abuse\n* body mass index (BMI) ≥ 35 kg m-2\n* Impairment of the patient's cognitive functions (such as Alzheimer's disease, dementia, etc.).\n* Cholecystectomy cases performed under emergency conditions.","ALL","18 Years","65 Years",{"count":68,"type":69},60,"ESTIMATED","INTERVENTIONAL",[72],"NA","Laparoscopic cholecystectomy, while less painful compared to conventional methods, is still a surgery that can cause significant pain for patients. Preventing postoperative pain is crucial for reducing respiratory complications, shortening hospital stays, and increasing patient satisfaction. Interfascial plane blocks have been widely used for postoperative analgesia in recent years worldwide. The External Oblique Intercostal Plane Block is one of the interfascial plane blocks used in abdominal surgeries. In our study, we aimed to compare the postoperative pain scores of patients who underwent laparoscopic cholecystectomy under general anesthesia, specifically between those who received the external oblique intercostal plane block and those who had trocar entry site infiltration.",[75,76,77,78],"Cholecystitis","Cholecystitis, Acute","Cholecystitis, Chronic","Cholecystitis; Gallstone",[80,81,82,83],"External Oblique Intercostal Plan Block","Wound Infiltration","Laparoscopic Cholecystectomy","Postoperative pain","2024-10-30",{"date":86,"type":87},"2024-11-01","ACTUAL",{"date":84,"type":87},{"date":90,"type":69},"2025-11-01",{"name":5,"class":6},1]