[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100618509":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":30,"centralContacts":35,"locations":43,"responsibleParty":67,"collaborators":25,"id":71,"slug":72,"hasResults":73,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":25,"eligibilityCriteria":77,"healthyVolunteers":73,"sex":78,"minAge":79,"maxAge":80,"enrollmentInfo":81,"targetDuration":25,"studyType":84,"phases":85,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":46,"whyStopped":25,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"Shanghai Pulmonary Hospital, Shanghai, China","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"EOIB Group","EXPERIMENTAL","Participants receive bilateral ultrasound-guided external oblique intercostal block (EOIB) (15 mL of the study local anesthetic mixture per side) in addition to standard general anesthesia and standardized postoperative analgesia (IV PCA butorphanol ).",[13],"Other: External oblique intercostal block (EOIB)",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","SHAM_COMPARATOR","Participants do not receive any regional block. They receive standard general anesthesia and standardized postoperative analgesia only (IV PCA butorphanol).",[19],"Other: Standard care without regional block",[21,26],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"External oblique intercostal block (EOIB)","Bilateral ultrasound-guided external oblique intercostal block performed under sterile conditions after induction of general anesthesia and before surgical incision. Using an in-plane technique, the block is performed at the level of the 6th rib in the 6th-7th intercostal space. A local anesthetic mixture is injected with a total volume of 15 mL per side (prepared by mixing 0.75% ropivacaine with normal saline).",[9],null,{"type":6,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Standard care without regional block","Participants do not receive any regional anesthesia\u002Fnerve block (including external oblique intercostal block). All participants receive standard general anesthesia and the same standardized postoperative multimodal analgesia regimen as per protocol, including intravenous patient-controlled analgesia (PCA) with butorphanol.",[15],[31],{"name":32,"affiliation":33,"role":34},"Xin Lv, PhD","Shanghai Pulmonary Hospital, Tongji University, Shanghai, China","STUDY_CHAIR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Shiyou Wei, Doc","CONTACT","15601680288","lovewishyou@tongji.edu.cn",{"name":42,"role":38,"phone":39,"phoneExt":25,"email":40},"Shiyou Y Wei",[44],{"facility":45,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"Tianmen First People's Hospital","RECRUITING","Tianmen","Hubei","431700","China","CN",{"type":53,"coordinates":54},"Point",[55,56],113.15369,30.65888,{"lat":56,"lon":55},[59,63],{"name":60,"role":38,"phone":61,"phoneExt":25,"email":62},"Jianmang Yu, Doc","8613094293728","yujianmang@hbust.edu.cn",{"name":64,"role":38,"phone":65,"phoneExt":25,"email":66},"Zhixiong Xiang, Doc","86-0728-5237400","28612363@qq.com",{"type":68,"investigatorFullName":69,"investigatorTitle":70,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"SPONSOR_INVESTIGATOR","Shiyou Wei","Principal Investigator","100618509","eoib-for-pain-after-laparoscopic-cholecystectomy-100618509",false,"NCT07332546","EOIB for Pain After Laparoscopic Cholecystectomy","External Oblique Intercostal Block for Postoperative Pain After Laparoscopic Cholecystectomy: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18-85 years, regardless of gender\n* American Society of Anesthesiologists (ASA) physical status classification I-III\n* Scheduled for elective laparoscopic cholecystectomy\n* Ability to use the intravenous patient-controlled analgesia (IV PCA) system\n\nExclusion Criteria:\n\n* Hepatic disease (e.g., liver enzyme levels ≥ 2× the upper limit of normal)\n* Renal disease (e.g., serum creatinine levels ≥ 2× the upper limit of normal)\n* Allergy or known hypersensitivity to local anesthetics\n* Females who are pregnant or lactating\n* Conversion to open surgery\n* Coagulopathy or current use of anticoagulant medications\n* Opioid use for more than 2 weeks in the past 6 months","ALL","18 Years","85 Years",{"count":82,"type":83},56,"ESTIMATED","INTERVENTIONAL",[86],"NA","This prospective, randomized, controlled, assessor-blinded trial will evaluate whether bilateral ultrasound-guided external oblique intercostal block (EOIB) reduces postoperative opioid consumption and improves pain control after laparoscopic cholecystectomy, compared with no block.",[89,90],"Postoperative Pain","Laparoscopic Cholecystectomy",[92,93,94,95],"External oblique intercostal block","Ultrasonography, Interventional","Nerve Block","Quality of recovery (QoR-15)","2026-06-06",{"date":98,"type":99},"2026-06-09","ACTUAL",{"date":101,"type":99},"2026-01-15",{"date":103,"type":83},"2026-07-05",{"name":69,"class":6},1]