[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633945":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":35,"locations":25,"responsibleParty":41,"collaborators":44,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":25,"eligibilityCriteria":53,"healthyVolunteers":49,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":25,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":25,"overallStatus":68,"whyStopped":25,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":25},{"fullName":5,"class":6},"Sohag University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Erector Spinae Plane Block Group","EXPERIMENTAL","Participants in this group will receive bilateral erector spinae plane block using local anesthetic for postoperative analgesia following open cholecystectomy.",[13],"Procedure: Erector Spinae Plane Block",{"label":15,"type":10,"description":16,"interventionNames":17},"External Oblique Intercostal Plane Block Group","Participants in this group will receive bilateral external oblique intercostal plane block using local anesthetic for postoperative analgesia following open cholecystectomy.",[18],"Procedure: External Oblique Intercostal Plane Block",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Erector Spinae Plane Block","Bilateral erector spinae plane block will be performed under ultrasound guidance using local anesthetic prior to surgical incision to provide postoperative analgesia.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"External Oblique Intercostal Plane Block","Bilateral external oblique intercostal plane block will be performed under ultrasound guidance using local anesthetic prior to surgical incision to provide postoperative analgesia.",[15],[31],{"name":32,"affiliation":33,"role":34},"Mohamed Mansour, MD","Professor of Anesthesia, ICU and Pain Management, Faculty of Medicine, Cairo University","PRINCIPAL_INVESTIGATOR",[36],{"name":37,"role":38,"phone":39,"phoneExt":25,"email":40},"Khaled M Hassan mohamed, MD","CONTACT","01153564555","dr.khalid.azab@gmail.com",{"type":34,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Salaheldin Ahmed Abdelziz","Anesthesia specialist",[45],{"name":46,"class":6},"Cairo University","100633945","erector-spinae-plane-block-versus-external-oblique-intercostal-plane-block-for-analgesia-in-open-cholecystectomy-100633945",false,"NCT07533279","Erector Spinae Plane Block Versus External Oblique Intercostal Plane Block for Analgesia in Open Cholecystectomy","Efficacy of Bilateral Erector Spinae Plane Block Versus Bilateral External Oblique Intercostal Plane Block for Perioperative Analgesia in Open Cholecystectomy Surgeries: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Adult patients aged 18-65 years.\n* Patients scheduled for elective open cholecystectomy.\n* American Society of Anesthesiologists (ASA) physical status I-II.\n* Patients who provide informed consent.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Known allergy to local anesthetics.\n* Coagulopathy or anticoagulant therapy.\n* Infection at the site of injection.\n* Severe hepatic, renal, or cardiac disease.\n* Body mass index (BMI) \\> 35 kg\u002Fm².\n* Pregnancy.","ALL","18 Years","65 Years",{"count":58,"type":59},66,"ESTIMATED","INTERVENTIONAL",[62],"NA","This randomized controlled trial aims to compare the analgesic efficacy of bilateral ultrasound-guided erector spinae plane block (ESPB) versus bilateral external oblique intercostal plane (EOI) block in patients undergoing open cholecystectomy.\n\nPatients will be randomly allocated into two groups to receive either ESPB or EOI block in addition to standard general anesthesia. The primary outcome is postoperative pain score assessed using the Numerical Rating Scale (NRS) at 2 hours after surgery. Secondary outcomes include intraoperative opioid consumption, postoperative nalbuphine requirements, time to first analgesic request, and hemodynamic changes.\n\nThis study seeks to determine the more effective regional anesthesia technique for improving perioperative analgesia in open cholecystectomy.",[65,66,22,67],"Cholecystectomy","Postoperative Pain","Regional Anesthesia","NOT_YET_RECRUITING","2026-04-09",{"date":71,"type":72},"2026-04-16","ACTUAL",{"date":74,"type":59},"2026-06",{"date":76,"type":59},"2027-05",{"name":5,"class":6}]