[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100568086":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":25,"centralContacts":29,"locations":40,"responsibleParty":64,"collaborators":25,"id":67,"slug":68,"hasResults":69,"nctId":70,"briefTitle":71,"officialTitle":72,"acronym":73,"eligibilityCriteria":74,"healthyVolunteers":69,"sex":75,"minAge":76,"maxAge":25,"enrollmentInfo":77,"targetDuration":25,"studyType":80,"phases":81,"briefSummary":83,"conditions":84,"keywords":87,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":101},{"fullName":5,"class":6},"National Taiwan University Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"adjuvanted","EXPERIMENTAL","adjuvanted (aIIV4) influenza vaccine",[13],"Drug: adjuvanted",{"label":15,"type":16,"description":17,"interventionNames":18},"non-adjuvanted","ACTIVE_COMPARATOR","non-adjuvanted (IIV4) influenza vaccine",[19],"Drug: non-adjuvanted",[21,26],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","adjuvanted (aIIV4) influenza vaccine in the Taiwanses elderly with chronic medical conditions",[9],null,{"type":22,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"non-adjuvanted (IIV4) influenza vaccine in the Taiwanses elderly with chronic medical conditions",[15],[30,36],{"name":31,"role":32,"phone":33,"phoneExt":34,"email":35},"Jann-Tay Wang Clinical Professor, M. D., Ph.D.","CONTACT","+886-2-2312-3456","263517","wangjt1124@ntuh.gov.tw",{"name":37,"role":32,"phone":33,"phoneExt":38,"email":39},"Un-In Wu Clinical Associate Professor, M. D.","265054","uninwu@gmail.com",[41],{"facility":5,"status":42,"city":43,"state":25,"zip":44,"country":45,"countryCode":46,"cosmosGeoPoint":47,"geoPoint":52,"contacts":53},"RECRUITING","Taipei","100225","Taiwan","TW",{"type":48,"coordinates":49},"Point",[50,51],121.52639,25.05306,{"lat":51,"lon":50},[54,58,62],{"name":55,"role":32,"phone":56,"phoneExt":34,"email":57},"Jann-Tay Wang, PhD","+886-2312-3456","wangjt1124@ntu.edu.tw",{"name":59,"role":32,"phone":56,"phoneExt":60,"email":61},"National Taiwan University Hospital Research Ethics Committee","288576","fctsai@ntu.edu.tw",{"name":55,"role":63,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"type":63,"investigatorFullName":65,"investigatorTitle":66,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"National Taiwan University Clinical Trial Center","Clinical professor","100568086","estimate-the-safety-and-effectiveness-of-adjuvanted-influenza-vaccine-among-asian-elderly-people-when-compared-to-non-adjuvanted-vaccines-100568086",false,"NCT06676644","Estimate the Safety and Effectiveness of Adjuvanted Influenza Vaccine Among Asian Elderly People When Compared to Non-adjuvanted Vaccines","A Comparative Study on the Immunogenicity and Safety of Adjuvanted Versus Non-Adjuvanted Influenza Vaccines in the Elderly","influenza","Inclusion Criteria:\n\n* Adults aged 65 years or above\n* Presence of at least 1 chronic medical condition associated with increased risk of complicated influenza, including hypertension, chronic obstructive pulmonary disease (group A, B, E), asthma, congestive heart failure (ACC\u002FAHA stage A, B, C, D), coronary arterial disease, diabetes mellitus, chronic liver disease (Child-Pugh score A, B, C) or chronic kidney disease (stage 1\\~4), neuromuscular disorders, hematological or solid organ malignancies, recipient of hematopoietic stem cell transplantation or solid organ transplantation.\n\nExclusion Criteria:\n\n* Contraindications to influenza vaccination including history of severe adverse event after vaccination, such as anaphylaxis or Guillain-Barré Syndrome, or a severe bleeding tendency\n* Prior receipt of influenza vaccination during the current flu season.\n* Determination by the Principal Investigator (PI) that the participant is ineligible for enrollment based on clinical assessment.","ALL","65 Years",{"count":78,"type":79},200,"ESTIMATED","INTERVENTIONAL",[82],"NA","To compare the immunogenicity, cellular immune response, and safety between adjuvanted (aIIV4) and non-adjuvanted (IIV4) seasonal influenza vaccines in the Taiwanese elderly population with chronic medical conditions.",[85,86],"Influenza Vaccines","Elderly",[73,88,89,90,91],"adjuvanted vaccine","immunogenicity","elderly","safety","2026-02-22",{"date":94,"type":95},"2026-02-24","ACTUAL",{"date":97,"type":95},"2024-11-21",{"date":99,"type":79},"2027-12-31",{"name":5,"class":6},1]