[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629796":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":15,"locations":25,"responsibleParty":47,"collaborators":51,"id":57,"slug":58,"hasResults":59,"nctId":60,"briefTitle":61,"officialTitle":61,"acronym":62,"eligibilityCriteria":63,"healthyVolunteers":59,"sex":64,"minAge":65,"maxAge":10,"enrollmentInfo":66,"targetDuration":10,"studyType":69,"phases":10,"briefSummary":70,"conditions":71,"keywords":75,"overallStatus":81,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"Institut d'Investigacions Biomèdiques August Pi i Sunyer","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"High Estimated First-Trimester Preeclampsia Risk",null,"Women with type 1 diabetes classified as high risk for preeclampsia during first-trimester screening in at least one prior pregnancy.",{"label":13,"type":10,"description":14,"interventionNames":10},"Low Estimated First-Trimester Preeclampsia Risk","Women with type 1 diabetes classified as low risk for preeclampsia during first-trimester screening in at least one prior pregnancy.",[16,21],{"name":17,"role":18,"phone":19,"phoneExt":10,"email":20},"Verónica Perea, MD, PhD","CONTACT","+34 93 736 50 50","vperea@mutuaterrassa.cat",{"name":22,"role":18,"phone":23,"phoneExt":10,"email":24},"Antonio J. Amor, MD, PhD","+34932279846","ajamor@clinic.cat",[26,38],{"facility":27,"status":10,"city":28,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":32,"geoPoint":37,"contacts":10},"Hospital Clínic Barcelona","Barcelona","08036","Spain","ES",{"type":33,"coordinates":34},"Point",[35,36],2.15899,41.38879,{"lat":36,"lon":35},{"facility":39,"status":10,"city":40,"state":40,"zip":41,"country":30,"countryCode":31,"cosmosGeoPoint":42,"geoPoint":46,"contacts":10},"Hospital Universitari Mútua Terrassa","Terrassa","08221",{"type":33,"coordinates":43},[44,45],2.01667,41.56667,{"lat":45,"lon":44},{"type":48,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Antonio J. Amor","Principal Investigator",[52,54],{"name":53,"class":6},"Hospital Mutua de Terrassa",{"name":55,"class":56},"Sociedad Española de Endocrinología y Nutrición","UNKNOWN","100629796","estimated-risk-of-preeclampsia-in-the-first-trimester-and-its-association-with-subclinical-atherosclerosis-and-cardiovascular-risk-in-women-with-type-1-diabetes-100629796",false,"NCT07479329","Estimated Risk of Preeclampsia in the First Trimester and Its Association With Subclinical Atherosclerosis and Cardiovascular Risk in Women With Type 1 Diabetes","PREEATH-T1D","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Confirmed diagnosis of type 1 diabetes\n* At least one prior pregnancy with first-trimester preeclampsia screening (\\\u003C14 weeks gestation)\n* ≥3 years since last pregnancy\n\nExclusion Criteria:\n\n* Previous multiple pregnancy\n* Cardiovascular disease before pregnancy (coronary heart disease, stroke\u002FTIA, peripheral artery disease, heart failure)\n* Active pregnancy at time of evaluation\n* Alcohol or substance dependence (except nicotine\u002Fcaffeine) in the last 3 years\n* Active severe psychiatric disease, dementia, severe disability, or reduced life expectancy","FEMALE","18 Years",{"count":67,"type":68},1300,"ESTIMATED","OBSERVATIONAL","This multicenter observational cohort study aims to evaluate whether estimated first-trimester risk of preeclampsia (PE) is associated with subclinical atherosclerosis, cardiovascular risk profile, and cardiovascular events in women with type 1 diabetes (T1D) at least 3 years after pregnancy.\n\nWomen with T1D and at least one prior pregnancy with documented first-trimester PE screening will be classified as high or low PE risk according to validated multivariable algorithms. The presence of carotid plaques, cardiometabolic risk factors, and incident cardiovascular events will be assessed during a study visit.",[72,73,74],"Type 1 Diabetes","Preeclampsia","Preeclampsia (PE) Risk",[72,73,76,77,78,79,80],"Preeclampsia Risk","Preclinical carotid atherosclerosis","Carotid ultrasonography","Cardiovascular risk","Cardiovascular disease","NOT_YET_RECRUITING","2026-03-16",{"date":84,"type":85},"2026-03-18","ACTUAL",{"date":87,"type":68},"2026-04-10",{"date":89,"type":68},"2028-04-30",{"name":5,"class":6},2]