[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100587950":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":37,"responsibleParty":65,"collaborators":26,"id":69,"slug":70,"hasResults":71,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":26,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":77,"minAge":78,"maxAge":26,"enrollmentInfo":79,"targetDuration":26,"studyType":82,"phases":83,"briefSummary":85,"conditions":86,"keywords":90,"overallStatus":39,"whyStopped":26,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":108},{"fullName":5,"class":6},"Lakehead University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Placebo","PLACEBO_COMPARATOR","Placebo (non-alcoholic beverage)",[13],"Drug: Placebo Beverage",{"label":15,"type":16,"description":17,"interventionNames":18},"Alcohol","ACTIVE_COMPARATOR","Consumption of alcohol beverages: females 0.75 ± 0.1 grams of ethanol\u002Fkilogram body mass; males 1.0 ± 0.1 grams of ethanol\u002Fkilogram body mass",[19],"Drug: Alcohol (Ethanol)",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DRUG","Placebo Beverage","Participants rest in a climate controlled room maintained at 40°C and 30%RH for 120 minutes follow placebo beverage consumption (180 minutes total).",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"Alcohol (Ethanol)","Participants rest in a climate controlled room maintained at 40°C and 30%RH for 120 minutes follow alcoholic beverage consumption (180 minutes total).",[15],[32],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Nicholas Ravanelli, PhD","CONTACT","18073438010","nravanel@nus.edu.sg",[38],{"facility":5,"status":39,"city":40,"state":41,"zip":42,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"RECRUITING","Thunder Bay","Ontario","P7B 5E1","Canada","CA",{"type":46,"coordinates":47},"Point",[48,49],-89.25018,48.38202,{"lat":49,"lon":48},[52,54,57,59,61,63],{"name":33,"role":34,"phone":53,"phoneExt":26,"email":36},"8073438010",{"name":55,"role":56,"phone":26,"phoneExt":26,"email":26},"KarLee Lefebvre, BHK","SUB_INVESTIGATOR",{"name":58,"role":56,"phone":26,"phoneExt":26,"email":26},"Amy Brough, BHK",{"name":60,"role":56,"phone":26,"phoneExt":26,"email":26},"Taryn Klarner, BHK",{"name":62,"role":56,"phone":26,"phoneExt":26,"email":26},"Nathan Morris, PhD",{"name":64,"role":56,"phone":26,"phoneExt":26,"email":26},"Georgia Chaseling, PhD",{"type":66,"investigatorFullName":67,"investigatorTitle":68,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"PRINCIPAL_INVESTIGATOR","Nicholas Ravanelli","Assistant Professor","100587950","ethanol-consumption-in-the-heat-100587950",false,"NCT06935045","Ethanol Consumption in the Heat","Evaluating How Alcohol Impacts Physiological Responses and Perception During Heat Exposure","Inclusion Criteria:\n\n* Male or Female above the age of 19\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* History of cardiovascular disease, cancer, type 1 or 2 diabetes, chronic obstructive pulmonary disorder, cystic fibrosis, or alcohol addiction or dependence\n* Been hospitalized due to COVID-19\n* Pregnant\u002FBreastfeeding\n* Scoring an eight or above on the Alcohol Use Disorders Identification Test (AUDIT)",true,"ALL","19 Years",{"count":80,"type":81},34,"ESTIMATED","INTERVENTIONAL",[84],"NA","Climate change has significantly increased the earth's average surface temperature and heat waves have been predicted to increase in frequency, intensity and duration. Extreme heat events have increased the susceptibility to heat-related illnesses, such as heat exhaustion, heat stroke or death. Heat health action plans have been designed to advertise cooling behaviours to mitigate physiological strain. Heat health action plans suggest avoiding alcohol consumption during extreme heat as it may increase dehydration and impair behavioural or physiological temperature regulation and thermal perception. Regardless of these messages, alcohol sales continue to remain high during the summer months year after year, and 1\u002F5 of adults identify alcohol as a hydration strategy during extreme heat events. A recent scoping review investigating the effects of alcohol and heat has demonstrated that acute alcohol consumption does not negatively influence thermoregulation, hydration, or hormone markers of fluid balance in the heat compared to a control fluid (https:\u002F\u002Fdoi.org\u002F10.1186\u002Fs12940-024-01113-y). Further, alcohol consumption may elicit sex- and age-specific alterations in physiological and perceptual responses, neither of which have been explored.\n\nTherefore, this study aims to comprehensively evaluate how alcohol consumption systematically alters physiological responses and perceptions during conditions similar to those experienced indoors during extreme heat events in younger and older adults.",[87,88,89],"Alcohol Consumption","Heat Stress","Age",[91,92,93,94,95,96,97,98],"alcohol","heat stress","heat wave","sweating","core temperature","micturition","perception","behaviour","2025-04-11",{"date":101,"type":102},"2025-04-18","ACTUAL",{"date":104,"type":102},"2023-12-04",{"date":106,"type":81},"2025-08",{"name":5,"class":6},1]