[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100622622":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":23,"centralContacts":27,"locations":32,"responsibleParty":48,"collaborators":10,"id":51,"slug":52,"hasResults":53,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":10,"eligibilityCriteria":57,"healthyVolunteers":53,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":64,"studyType":65,"phases":10,"briefSummary":66,"conditions":67,"keywords":73,"overallStatus":34,"whyStopped":10,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},{"fullName":5,"class":6},"Tianjin Huanhu Hospital","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"FOG Group",null,"This cohort includes participants with freezing of gait present at baseline. Participants may have Parkinson's disease or other neurological conditions associated with freezing of gait. All participants receive standard clinical care as determined by their treating physicians. No experimental treatments or study-specific interventions are assigned as part of this observational registry.",[13],"Other: Observational Data Collection",{"label":15,"type":10,"description":16,"interventionNames":17},"High-Risk Group","This cohort includes participants with gait or balance impairment who have not developed freezing of gait at baseline but are considered at high risk for future freezing of gait. Participants may have Parkinson's disease or related neurological disorders. All participants receive standard clinical care, and no experimental treatments or study-specific interventions are provided as part of this observational registry.",[13],[19],{"type":6,"name":20,"description":21,"armGroupLabels":22,"otherNames":10},"Observational Data Collection","This is an observational patient registry. No experimental drugs, devices, or procedures are assigned as part of the study. All participants receive standard medical care, and data are collected during routine clinical visits and follow-up assessments.",[9,15],[24],{"name":25,"affiliation":5,"role":26},"Peipei Liu, MD","PRINCIPAL_INVESTIGATOR",[28],{"name":25,"role":29,"phone":30,"phoneExt":10,"email":31},"CONTACT","86-13512204476","pddoctorpipi2021@163.com",[33],{"facility":5,"status":34,"city":35,"state":36,"zip":37,"country":38,"countryCode":39,"cosmosGeoPoint":40,"geoPoint":45,"contacts":46},"RECRUITING","Tianjin","Tianjin Municipality","300350","China","CN",{"type":41,"coordinates":42},"Point",[43,44],117.17667,39.14222,{"lat":44,"lon":43},[47],{"name":25,"role":29,"phone":30,"phoneExt":10,"email":31},{"type":26,"investigatorFullName":49,"investigatorTitle":50,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Peipei Liu","Principal Investigator","100622622","etiology-phenotype-outcome-pathway-study-on-freezing-of-gait-fog-100622622",false,"NCT07386015","Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)","FREEZE-Path Cohort: Etiology-Phenotype-Outcome Pathway Study on Freezing of Gait (FOG)","Inclusion Criteria:\n\n1. Age 30-85 years\n2. Presence of freezing of gait or non-freezing gait or balance impairment\n3. Diagnosis of Parkinson's disease or related parkinsonian disorders according to established international criteria (including PD, PSP, MSA, DLB, CBD, vascular parkinsonism, or idiopathic normal pressure hydrocephalus)\n4. Ability to complete gait and balance assessment tasks independently or with assistance\n5. Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n1. Severe dementia (Mini-Mental State Examination score \\\u003C 10)\n2. Severe psychiatric disorders interfering with study participation\n3. Severe cardiopulmonary, musculoskeletal, or other medical conditions significantly affecting gait safety\n4. Stroke, fracture, or other major medical events within the past 3 months\n5. Inability to comply with follow-up procedures\n6. Refusal of video or speech data collection","ALL","30 Years","85 Years",{"count":62,"type":63},700,"ESTIMATED","36 Months","OBSERVATIONAL","This study is a prospective, multicenter, observational cohort (patient registry) designed to better understand freezing of gait (FOG), a disabling walking problem that can occur in Parkinson's disease and other related neurological conditions.The purpose of this registry is to collect long-term clinical information from patients with freezing of gait or gait and balance problems, and to explore how different causes of FOG are related to symptoms, walking patterns, falls, disease progression, and outcomes over time. The study will include participants with Parkinson's disease and other conditions associated with freezing of gait.Participants will receive standard medical care as determined by their treating physicians. No experimental drugs or study-related treatments will be assigned as part of this registry. Clinical information will be collected during routine visits and follow-up assessments, including questionnaires, walking and balance evaluations, video recordings, and other commonly used clinical tests.The information collected in this study may help improve the understanding of freezing of gait, support better risk assessment for falls, and guide future research and clinical management strategies for patients with gait and balance disorders.",[68,69,70,71,72],"Freezing of Gait","Parkinson's Disease","Parkinsonism","Vascular Parkinsonism","Idiopathic Normal Pressure Hydrocephalus (INPH)",[68,69,74],"parkinsonism","2026-03-08",{"date":77,"type":78},"2026-03-10","ACTUAL",{"date":80,"type":78},"2026-02-28",{"date":82,"type":63},"2030-11-30",{"name":5,"class":6},1]