[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100492057":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":37,"centralContacts":10,"locations":44,"responsibleParty":77,"collaborators":79,"id":83,"slug":84,"hasResults":85,"nctId":86,"briefTitle":87,"officialTitle":87,"acronym":10,"eligibilityCriteria":88,"healthyVolunteers":85,"sex":89,"minAge":90,"maxAge":10,"enrollmentInfo":91,"targetDuration":10,"studyType":94,"phases":10,"briefSummary":95,"conditions":96,"keywords":98,"overallStatus":60,"whyStopped":10,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":111},{"fullName":5,"class":6},"H. Lee Moffitt Cancer Center and Research Institute","OTHER",[8,12],{"label":9,"type":10,"description":11,"interventionNames":10},"Retrospective Cohort",null,"Retrospective chart review and sample analysis of both pathologically confirmed Pancreatic Ductal Adenocarcinoma (PDAC) cases and non-Cancer control cases.",{"label":13,"type":10,"description":14,"interventionNames":15},"Prospective Cohort","Blood samples, tissue samples and data will be collected from all participants as applicable.",[16,17,18,19],"Other: Blood Sample Collection","Other: Tissue Sample Collection","Other: Data Collection","Other: Medical Image Collection",[21,25,29,33],{"type":6,"name":22,"description":23,"armGroupLabels":24,"otherNames":10},"Blood Sample Collection","Participants will have 40 mL of blood drawn at baseline\u002Fpre-treatment. The study team will aim to have this blood collected at the time of standard of care blood draw if possible.",[13],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":10},"Tissue Sample Collection","At the time of tissue biopsy or surgical resection (if applicable) pancreatic tumor tissue, fat, tissue from site of metastasis, and cyst fluid (if applicable) will be collected.",[13],{"type":6,"name":30,"description":31,"armGroupLabels":32,"otherNames":10},"Data Collection","Participants will complete a study questionnaire at baseline that includes medical history, lifestyle, and family history information.",[13],{"type":6,"name":34,"description":35,"armGroupLabels":36,"otherNames":10},"Medical Image Collection","Medical images that are obtained during routine care such as computed tomography (CT) scans, magnetic resonance imaging (MRIs) and ultrasounds will be reviewed by the study team throughout the participant's medical care.",[13],[38,42],{"name":39,"affiliation":40,"role":41},"Jennifer Permuth, PhD, MS","Moffitt Cancer Center","PRINCIPAL_INVESTIGATOR",{"name":43,"affiliation":40,"role":41},"Mokenge Malafa, MD",[45,58],{"facility":40,"status":46,"city":47,"state":48,"zip":49,"country":50,"countryCode":51,"cosmosGeoPoint":52,"geoPoint":57,"contacts":10},"ACTIVE_NOT_RECRUITING","Tampa","Florida","33612","United States","US",{"type":53,"coordinates":54},"Point",[55,56],-82.45843,27.94752,{"lat":56,"lon":55},{"facility":59,"status":60,"city":61,"state":62,"zip":63,"country":50,"countryCode":51,"cosmosGeoPoint":64,"geoPoint":68,"contacts":69},"University of Mississippi Medical Center","RECRUITING","Jackson","Mississippi","39216",{"type":53,"coordinates":65},[66,67],-90.18481,32.29876,{"lat":67,"lon":66},[70,75],{"name":71,"role":72,"phone":73,"phoneExt":10,"email":74},"Magdeline D Martin","CONTACT","352-672-0548","MDMartin@umc.edu",{"name":76,"role":41,"phone":10,"phoneExt":10,"email":10},"Shannon Orr, MD",{"type":78,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[80],{"name":81,"class":82},"United States Department of Defense","FED","100492057","evaluating-obesity-mediated-mechanisms-of-pancreatic-carcinogenesis-in-minority-populations-100492057",false,"NCT05687188","Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations","Inclusion Criteria:\n\n* Adults 18 years of age or older at time of signing informed consent\n* Patients who self-report as African American, Non-Hispanic White\n* Patients who present to the gastrointestinal (GI) clinic, surgery, or endoscopy at a participating Florida Pancreas Collaborative (FPC) site or the University of Mississippi Medical Center (UMMC) with a clinical suspicion or diagnosis of a pancreatic tumor.\n\nExclusion Criteria:\n\n* Patient under 18 years of age\n* Has no suspicion or diagnosis of a pancreatic cancer or tumor\n* Self-reported race\u002Fethnicity other than African American or Non-Hispanic White.","ALL","18 Years",{"count":92,"type":93},125,"ESTIMATED","OBSERVATIONAL","This study will evaluate obesity-mediated mechanisms of pancreatic carcinogenesis in minority populations.",[97],"Pancreatic Cancer",[99,100,101],"pancreas","biomarkers","health disparities","2026-05-21",{"date":104,"type":105},"2026-05-26","ACTUAL",{"date":107,"type":105},"2023-02-22",{"date":109,"type":93},"2026-12",{"name":5,"class":6},2]