[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100588668":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":27,"responsibleParty":44,"collaborators":20,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":52,"acronym":20,"eligibilityCriteria":53,"healthyVolunteers":50,"sex":54,"minAge":55,"maxAge":20,"enrollmentInfo":56,"targetDuration":20,"studyType":59,"phases":60,"briefSummary":62,"conditions":63,"keywords":20,"overallStatus":29,"whyStopped":20,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"Northwestern University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Taking pumpkin seed extract","EXPERIMENTAL","Upon a patient's enrollment into the study and completion of initial study questionnaires, a research team member will provide the patient with a single bottle of pumpkin seed oil extract. Enrolled patients will be instructed to initiate using the pumpkin seed oil extract starting the day they receive the supplement. Patients will start taking one pill by mouth per day for 12 weeks. They will also be advised to contact their urogynecologist for follow-up if they have not noticed improvement in their bladder health following 3 months of use. Furthermore, they will be counseled about not starting new medications or supplements during their time as a study participant and not sharing their pumpkin seed oil extract with anyone else during their time as a study participant.",[13],"Dietary Supplement: Pumpkin Seed Extract",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DIETARY_SUPPLEMENT","Pumpkin Seed Extract","This is the only intervention",[9],null,[22],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Julia Geynisman-Tan, MD","CONTACT","312-926-9929","Julia.Geynisman-Tan@nm.org",[28],{"facility":5,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"RECRUITING","Chicago","Illinois","60611","United States","US",{"type":36,"coordinates":37},"Point",[38,39],-87.65005,41.85003,{"lat":39,"lon":38},[42],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":43},"julia.geynisman-tan@nm.org",{"type":45,"investigatorFullName":46,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":20,"oldOrganization":20},"PRINCIPAL_INVESTIGATOR","Julia Geynisman-Tan","Professor","100588668","evaluating-pumpkin-seed-oil-extract-supplementation-on-bladder-function-100588668",false,"NCT06944392","Evaluating Pumpkin Seed Oil Extract Supplementation on Bladder Function","Inclusion Criteria:\n\n* All patients evaluated at Northwestern's IPHP who report bladder function consistent with overactive bladder (urinary urgency, with or without urinary frequency more than 8 times daily or nocturia, with or without urgency urinary incontinence) at their index visit, who are also willing to use a dietary supplement and not initiate additional behavioral, medication or procedural treatment for 12 weeks following pumpkin seed oil extract initiation.\n\nExclusion Criteria:\n\n* Patients with any of the following will be excluded from the study:\n* Use of other supplements that contain pumpkin seed oil\n* ≥Stage 3 pelvic organ prolapse\n* Urinary post-void residual ≥150cc\n* Culture-proven urinary tract infection at time of study enrollment\n* Recurrent urinary tract infection\n* Neurogenic bladder\n* Abdominal or pelvic malignancy\n* Initiation of new overactive bladder medications or supplements during study period or in the 3 months immediately preceding study enrollment\n* History of surgery in the past 12 months for pelvic organ prolapse, stress urinary incontinence, urgency urinary incontinence, or fecal or flatal incontinence\n* Patient's primary language is not English","FEMALE","18 Years",{"count":57,"type":58},40,"ESTIMATED","INTERVENTIONAL",[61],"NA","This is a pilot study to assess using validated outcome measures how ingesting pumpkin seed oil extract supports patient bladder function in a United States population.",[64],"Overactive Bladder (OAB)","2026-04-22",{"date":67,"type":68},"2026-04-23","ACTUAL",{"date":70,"type":68},"2025-04-11",{"date":72,"type":58},"2026-10-01",{"name":5,"class":6},1]