[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100623903":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":12,"locations":18,"responsibleParty":35,"collaborators":39,"id":44,"slug":45,"hasResults":46,"nctId":47,"briefTitle":48,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":46,"sex":51,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":7,"studyType":57,"phases":7,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":21,"whyStopped":7,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":74},{"fullName":5,"class":6},"University Children's Hospital, Zurich","OTHER",null,[9],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Trauma-focused Cognitive Behavioral Therapy for Children and Adolescents","TF-CBT is a child and family-focused, component-based trauma-focused intervention that aims to address post-traumatic stress symptoms and other trauma-related difficulties (e.g., anxiety, depression) associated with traumatic events.",[13],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},"Lasse Bartels, PhD","CONTACT","+41 44 249 56 60","lasse.bartels@kispi.uzh.ch",[19],{"facility":20,"status":21,"city":22,"state":23,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"University Children's Hospital Zurich","RECRUITING","Zurich","Canton of Zurich","8008","Switzerland","CH",{"type":28,"coordinates":29},"Point",[30,31],8.55,47.36667,{"lat":31,"lon":30},[34],{"name":14,"role":15,"phone":16,"phoneExt":7,"email":17},{"type":36,"investigatorFullName":37,"investigatorTitle":38,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Lasse Bartels","Postdoctoral fellow",[40,42],{"name":41,"class":6},"Otto-Friedrich-University Bamberg",{"name":43,"class":6},"Catholic University of Eichstätt-Ingolstadt","100623903","evaluating-symptom-variations-and-observing-longitudinal-individual-change-effects-in-tf-cbt-100623903",false,"NCT07402681","Evaluating Symptom Variations and Observing Longitudinal Individual Change Effects in TF-CBT","EVOLVE","Participants will be included if:\n\n1. they are between 12 and 18 years of age;\n2. they have been exposed to at least one or more traumatic event(s) according to the DSM-5 A criteria after the age of 3 years and dating back at least 1 months (with regard to the ability of patients to remember the event(s) and to the high spontaneous remissions of PTSS in the first month after a traumatic event);\n3. they exhibit high severity of DSM-5 PTSS as indicated by a total symptom score of ≥25 assessed with the Child and Adolescent Trauma Screen 2 (CATS-2);\n4. a nonoffending adult caregiver is available for the treatment and willing to participate in weekly treatment sessions (the inclusion of a caregiver is integral to the TF-CBT treatment model);\n5. they are willing and able to attend weekly treatment sessions;\n6. if their living circumstances are safe and stable to minimize the risk of re-traumatization during the project;\n7. they and their caregiver have sufficient command of the German language (i.e., to participate in assessment \\[read\\] and treatment\\[converse\\]);\n8. they and their caregivers possess a smartphone.\n9. they and their caregiver provided written informed consent.\n\nParticipants will not be included if:\n\n1. they exhibit acute suicidal behavior or have suicidal ideations requiring immediate hospitalization;\n2. they have a documented developmental disorder (i.e., autism spectrum disorder) or current psychosis based on adolescent- and caregiver-report and clinical assessment;\n3. they exhibit severe substance misuse based on clinical assessment;\n4. take part in concurrent psychotherapy during TF-CBT;\n5. exhibit severe intellectual disability based on clinical assessment.","ALL","12 Years","18 Years",{"count":55,"type":56},21,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the level of change in post-traumatic stress symptoms in adolescents with traumatic experiences over the course of trauma-focused cognitive behavioral therapy for children and adolescents according to Cohen, Manarinno, \\& Deblinger (2017).",[60],"Post-traumatic Stress Symptoms",[62,63,64],"TF-CBT","post-traumatic stress symptoms","single-case experimental design","2026-02-04",{"date":67,"type":68},"2026-02-11","ACTUAL",{"date":70,"type":56},"2026-02",{"date":72,"type":56},"2027-12",{"name":5,"class":6},1]