[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100607332":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":26,"centralContacts":31,"locations":41,"responsibleParty":60,"collaborators":26,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":26,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":71,"minAge":72,"maxAge":26,"enrollmentInfo":73,"targetDuration":26,"studyType":76,"phases":77,"briefSummary":79,"conditions":80,"keywords":83,"overallStatus":44,"whyStopped":26,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":98},{"fullName":5,"class":6},"The Cleveland Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Control - Holmium","ACTIVE_COMPARATOR","Holmium laser enucleation",[13],"Device: holmium laser",{"label":15,"type":16,"description":17,"interventionNames":18},"Experimental - Thulio","EXPERIMENTAL","Thulio laser enucleation",[19],"Device: pulsed thulium laser",[21,27],{"type":22,"name":23,"description":24,"armGroupLabels":25,"otherNames":26},"DEVICE","holmium laser","Prostate enucleation will holmium laser (control)",[9],null,{"type":22,"name":28,"description":29,"armGroupLabels":30,"otherNames":26},"pulsed thulium laser","experimental group - pulsed thulium laser prostate enucleation",[15],[32,37],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},"Iva Markovic","CONTACT","216-636-9694","markovi@ccf.org",{"name":38,"role":34,"phone":39,"phoneExt":26,"email":40},"Smita De, MD, PHD","216-445-4818","des@ccf.org",[42],{"facility":43,"status":44,"city":45,"state":46,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Cleveland Clinic Main","RECRUITING","Cleveland","Ohio","44195","United States","US",{"type":51,"coordinates":52},"Point",[53,54],-81.69541,41.4995,{"lat":54,"lon":53},[57,58],{"name":33,"role":34,"phone":35,"phoneExt":26,"email":36},{"name":59,"role":34,"phone":39,"phoneExt":26,"email":40},"Smita De, MD, PhD",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":26,"oldOrganization":26},"SPONSOR_INVESTIGATOR","Smita De","Principal Investigator","100607332","evaluating-the-clinical-efficacy-of-thulio-vs-holmium-laser-enucleation-of-the-prostate-100607332",false,"NCT07187180","Evaluating the Clinical Efficacy of Thulio vs. Holmium Laser Enucleation of the Prostate","Inclusion Criteria:\n\n* Understand and voluntarily sign an informed consent form.\n* Patients must be males with a prostate, at least 18 years of age\n* No prior prostate surgery\n\nExclusion Criteria:\n\n* Unable\u002Frefuse to provide informed consent\n* Prior prostate surgery\n* Bladder stones that requiring lasering (small stone that can be removed whole is ok)\n* Unable to hold anticoagulants or antiplatelets per standard protocols for surgery and up to 1 week postop.",true,"MALE","18 Years",{"count":74,"type":75},50,"ESTIMATED","INTERVENTIONAL",[78],"NA","Many consider laser enucleation of the prostate the new 'gold standard' for the surgical treatment of benign prostatic hyperplasia (BPH) due to its excellent outcomes, high success rates, and long-term efficacy. Holmium laser enucleation of the prostate (HoLEP) was the earliest form of prostate enucleation and is recommended by the American Urological Association (AUA), along with thulium laser enucleation of the prostate (ThuLEP), as size-independent techniques for the management of BPH with fewer complications than transurethral resection of the prostate (TURP). Further development of laser technology has additionally led to enucleation using pulsed-modulated (e.g. \"Virtual Basket™\" mode or MOSES™ mode) holmium lasers as well as the thulium fiber laser.",[81,82],"BPH With Symptomatic Lower Urinary Tract Symptoms","BPH With Urinary Obstruction",[84,85,86,87,88],"BPH","Enlarged prostate","Thulio laser","Prostate enucleation","male urinary retention","2025-09-16",{"date":91,"type":92},"2025-09-22","ACTUAL",{"date":94,"type":92},"2025-06-02",{"date":96,"type":75},"2026-09",{"name":62,"class":6},1]