[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100598060":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":18,"centralContacts":25,"locations":18,"responsibleParty":31,"collaborators":35,"id":39,"slug":40,"hasResults":41,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":45,"eligibilityCriteria":46,"healthyVolunteers":41,"sex":47,"minAge":48,"maxAge":18,"enrollmentInfo":49,"targetDuration":18,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":61,"overallStatus":64,"whyStopped":18,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":18},{"fullName":5,"class":6},"Istanbul University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Valsalva Maneuver Group","EXPERIMENTAL","Patients perform the Valsalva maneuver during AVF cannulation in each dialysis session.",[13],"Behavioral: Valsalva Maneuver",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group","NO_INTERVENTION","Patients receive standard AVF cannulation care without any additional intervention.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":18},"BEHAVIORAL","Valsalva Maneuver","Patients are instructed to perform the Valsalva maneuver by blowing into a 10-cc syringe to generate approximately 20 mmHg pressure for 15-20 seconds before arteriovenous fistula cannulation during each dialysis session.",[9],[26],{"name":27,"role":28,"phone":29,"phoneExt":18,"email":30},"Cansu Polat Dunya, Assoc Prof","CONTACT","0905452818917","cansu.polat@istanbul.edu.tr",{"type":32,"investigatorFullName":33,"investigatorTitle":34,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","Cansu POLAT DÜNYA","PhD, Associate Professor",[36],{"name":37,"class":38},"Istanbul University Scientific Research Projects Coordination Unit- Pending","UNKNOWN","100598060","evaluating-the-effect-of-the-valsalva-maneuver-on-invasive-pain-during-arteriovenous-fistula-cannulation-in-hemodialysis-patients-100598060",false,"NCT07066579","Evaluating the Effect of the Valsalva Maneuver on Invasive Pain During Arteriovenous Fistula Cannulation in Hemodialysis Patients","Evaluation of the Effect of the Valsalva Maneuver on Invasive Pain During Arteriovenous Fistula Cannulation in Hemodialysis Patients","VALPAIN-HD","Inclusion Criteria:\n\n* Age 18 years or older\n* Receiving hemodialysis treatment via arteriovenous fistula for at least 3 months\n* No analgesic medication use within the past 24 hours\n* Systolic blood pressure between 90-160 mmHg and diastolic between 60-100 mmHg\n* Pain score ≥ 1 on Visual Analogue Scale during AVF cannulation\n* Able to perform the Valsalva maneuver (no contraindications)\n* No communication barriers or severe psychiatric disorders\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Unable to correctly perform the Valsalva maneuver\n* Failed first cannulation attempt\n* History of acute myocardial infarction or malignant arrhythmia\n* Aneurysm, infection, edema, or scar tissue at AVF site\n* Pregnancy\n* Voluntary withdrawal from the study at any stage\n* Switching dialysis centers or requiring hospitalization during the study","ALL","18 Years",{"count":50,"type":51},60,"ESTIMATED","INTERVENTIONAL",[54],"NA","The goal of this clinical trial is to evaluate whether the Valsalva maneuver reduces invasive pain during arteriovenous fistula (AVF) cannulation in adult hemodialysis patients. The main questions it aims to answer are:\n\nDoes the Valsalva maneuver effectively reduce pain intensity during AVF cannulation as measured by the Visual Analogue Scale (VAS)?\n\nIs the Valsalva maneuver feasible, acceptable, and satisfactory for patients, and can it be sustainably implemented over multiple sessions?\n\nResearchers will compare patients performing the Valsalva maneuver (intervention group) with those receiving standard care without any intervention (control group) to see if pain scores are significantly lower and whether patients are willing to continue using this technique voluntarily.\n\nParticipants will:\n\nReceive training and supervised practice on the Valsalva maneuver before inclusion in the study\n\nPerform the Valsalva maneuver during AVF cannulation in each hemodialysis session for 12 sessions\n\nComplete VAS pain assessments after each session\n\nComplete a patient satisfaction and feasibility form at the end of the study",[57,58,59,60],"Arteriovenous Fistula","Pain","Hemodialysis Access Failure","Vascular Access Device Complications",[62,57,63,22],"Hemodialysis","Cannulation Pain","NOT_YET_RECRUITING","2025-07-05",{"date":67,"type":68},"2025-07-15","ACTUAL",{"date":70,"type":51},"2025-09-01",{"date":72,"type":51},"2026-09-01",{"name":33,"class":6}]