[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100477116":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":37,"locations":47,"responsibleParty":62,"collaborators":25,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":25,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":25,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":25,"overallStatus":49,"whyStopped":25,"lastUpdateSubmitDate":84,"lastUpdatePostDateStruct":85,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":93},{"fullName":5,"class":6},"Hama University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Micro-osteoperforations","EXPERIMENTAL","Experimental: Micro-Osteoperforations Technique(MOPs) Experimental: Micro-Osteoperforations Technique(MOPs) Surgery will be performed to the lower anterior bony segment of the lower jaw in order to accelerate tooth movement.",[13],"Device: Micro-osteoperforations Technique",{"label":15,"type":10,"description":16,"interventionNames":17},"Clear aligner","Traditional treatment The patients in this group will be receive treatment with the traditional clear aligners technique without any surgical procedure.",[18],"Device: Active comparater",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Micro-osteoperforations Technique","Micro-Osteoperforations Technique (MOPs) Surgery will be performed to the lower anterior bony segment of the lower jaw in order to accelerate tooth movement.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Active comparater","Active Comparator: Traditional treatment The patients in this group will be receive treatment with the traditional clear aligners technique without any surgical procedure.",[15],[31,34],{"name":32,"affiliation":5,"role":33},"Zouha Barram","PRINCIPAL_INVESTIGATOR",{"name":35,"affiliation":5,"role":36},"Rabab AlSabbag, Professor","STUDY_DIRECTOR",[38,43],{"name":39,"role":40,"phone":41,"phoneExt":25,"email":42},"Zouha Barram, MSc Student","CONTACT","00963964617577","barramzouha@gmail.com",{"name":44,"role":40,"phone":45,"phoneExt":25,"email":46},"Fadi Jnaid, DDS,MSc,PhD","00963988499015","Drfadijnaid@gmail.com",[48],{"facility":5,"status":49,"city":50,"state":25,"zip":25,"country":51,"countryCode":25,"cosmosGeoPoint":52,"geoPoint":57,"contacts":58},"RECRUITING","Hama","Syria",{"type":53,"coordinates":54},"Point",[55,56],36.75783,35.13179,{"lat":56,"lon":55},[59],{"name":60,"role":40,"phone":61,"phoneExt":25,"email":46},"Fadi Jnaid","988499015",{"type":63,"investigatorFullName":25,"investigatorTitle":25,"investigatorAffiliation":25,"oldNameTitle":25,"oldOrganization":25},"SPONSOR","100477116","evaluating-the-efficacy-of-micro-osteoperforations-technique-on-the-orthodontic-tooth-movement-acceleration-in-moderate-mandibular-anterior-crowding-cases-treated-with-clear-aligners-100477116",false,"NCT05492773","Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration in Moderate Mandibular Anterior Crowding Cases Treated With Clear Aligners","Evaluating the Efficacy of Micro-Osteoperforations Technique on the Orthodontic Tooth Movement Acceleration of Dental Crowding Cases Treated With Clear Aligners: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Completion of permanent dentition (except third molars)\n* Moderate crowding (4-6 mm according to Little's index)\n* Absence of medications intake that interferes with pain perception for at least one week before the beginning of the treatment\n* Number of aligners ≥ 8 aligners.\n\nExclusion Criteria:\n\n* • Systematic diseases that could affect bone and tooth movement and no contraindication avoid oral surgery\n\n  * Medical conditions that affect tooth movement (Corticosteroid, NSAIDs)\n  * Patients had previous orthodontic treatments\n  * Poor oral hygiene or concurrent periodontal disease",true,"ALL","18 Years","26 Years",{"count":76,"type":77},30,"ESTIMATED","INTERVENTIONAL",[80],"NA","Patients with moderate mandibular anterior crowding will be treated in this study. The efficacy of micro-osteoperforations technique by special drill in accelerating orthodontic tooth movement during clear aligners therapy will be assessed along with patient's pain and satisfaction.\n\nThere are two groups:\n\n1. a group of patients in which participants will be received treatment with the traditional clear aligners technique in addition to a micro-osteoperforations technique.\n2. a group of patients in which participants will be received treatment with the traditional clear aligners technique alone",[83],"Crowding of Anterior Mandibular Teeth","2025-09-09",{"date":86,"type":87},"2025-09-15","ACTUAL",{"date":89,"type":77},"2026-06-10",{"date":91,"type":77},"2026-12-04",{"name":5,"class":6},1]