[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100608985":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":24,"centralContacts":28,"locations":33,"responsibleParty":67,"collaborators":70,"id":74,"slug":75,"hasResults":76,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":76,"sex":82,"minAge":83,"maxAge":18,"enrollmentInfo":84,"targetDuration":18,"studyType":87,"phases":88,"briefSummary":90,"conditions":91,"keywords":93,"overallStatus":36,"whyStopped":18,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":105},{"fullName":5,"class":6},"The Cleveland Clinic","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Arm","EXPERIMENTAL","The ACT-BP protocol will be implemented in the intervention units. First, the study team will implement an order on the unit that prompts the nurses to follow the ACT-BP algorithm when a patient has an asymptomatic elevated BP between 160mmHg and 199mmHg. This protocol does not apply to patients who are experiencing hypertensive emergencies or cardiac symptoms. To increase adherence to the ACT-BP protocol, knowledge related to treating the potential underlying causes of an asymptomatically elevated BP and the current state of the evidence will be shared through posters, information sheets and knowledge sessions.\n\nAt the the intervention hospital, the study team will provide caregivers (including physicians) with knowledge related to the state of the evidence for treating asymptomatically elevated BPs through emails, information sheets and one-pagers.",[13],"Other: ACT-BP Intervention",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Arm","NO_INTERVENTION","In the control units, care will continue as usual.\n\nAt the the control hospital, caregivers (including physicians) will receive knowledge related to the state of the evidence for treating asymptomatically elevated BPs through an email.",null,[20],{"type":6,"name":21,"description":22,"armGroupLabels":23,"otherNames":18},"ACT-BP Intervention","In our intervention units, the study team will change the unit-based protocols to follow the ACT-BP intervention. First, it prompts the nurse to identify if a patient is experiencing hypertensive emergencies or cardiac symptoms. If so, it suggests calling the physician. If not, it prompts assessment for pain, anxiety, nausea, or hunger and provides evidence-based suggestions. It also prompts monitoring to enhance patients' safety in the case of rapidly rising BP. This algorithm will provide a path for ensuring patients receive appropriate treatment.",[9],[25],{"name":26,"affiliation":5,"role":27},"Elizabeth Pfoh, PhD, MPH","PRINCIPAL_INVESTIGATOR",[29],{"name":26,"role":30,"phone":31,"phoneExt":18,"email":32},"CONTACT","12162963034","pfohe@ccf.org",[34,55],{"facility":35,"status":36,"city":37,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Cleveland Clinic Main Campus","RECRUITING","Cleveland","Ohio","44195","United States","US",{"type":43,"coordinates":44},"Point",[45,46],-81.69541,41.4995,{"lat":46,"lon":45},[49,53],{"name":50,"role":30,"phone":51,"phoneExt":18,"email":52},"Emma J Wensink","216-442-5341","wensine2@ccf.org",{"name":54,"role":27,"phone":18,"phoneExt":18,"email":18},"Elizabeth Pfoh",{"facility":56,"status":36,"city":57,"state":38,"zip":58,"country":40,"countryCode":41,"cosmosGeoPoint":59,"geoPoint":63,"contacts":64},"Cleveland Clinic Hillcrest","Mayfield Heights","44124",{"type":43,"coordinates":60},[61,62],-81.4579,41.51922,{"lat":62,"lon":61},[65,66],{"name":50,"role":30,"phone":51,"phoneExt":18,"email":52},{"name":54,"role":27,"phone":18,"phoneExt":18,"email":18},{"type":68,"investigatorFullName":54,"investigatorTitle":69,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"SPONSOR_INVESTIGATOR","Staff\u002FAssociate Professor of Medicine",[71],{"name":72,"class":73},"National Heart, Lung, and Blood Institute (NHLBI)","NIH","100608985","evaluating-whether-treating-elevated-blood-pressure-in-the-inpatient-setting-impacts-patient-outcomes-100608985",false,"NCT07208669","Evaluating Whether Treating Elevated Blood Pressure in the Inpatient Setting Impacts Patient Outcomes","Evaluating Whether Treating Elevated Blood Pressure in the Inpatient Setting Impacts Patient Outcomes: the ACT-BP Pilot","ACT-BP","Inclusion Criteria:\n\n* At the unit level: Medical units that do not typically care for patients requiring step-down care.\n\nExclusion Criteria:\n\n1. Patients less than 18\n2. Patients experiencing hypertensive emergencies or cardiac symptoms\n3. Patients with active cardiovascular events, such as\n\n   * Stroke\n   * Non-ST-elevation\n   * Myocardial infarction\n   * End-stage renal disease\n   * Patients on dialysis\n   * Those with acute decompensated heart failure\n\n3\\. Patients on the unit for more than 10 days\n\n4\\. Patients transferred in after being in the intensive care unit (ICU)\n\n5\\. Pregnant and post-partum women\n\n6\\. Patients discharged within 24 hours of admission\n\n7\\. Patients whose systolic BP remains below 160 mmHg during hospitalization.","ALL","18 Years",{"count":85,"type":86},4,"ESTIMATED","INTERVENTIONAL",[89],"NA","The vast majority of the 36.2 million individuals admitted to U.S. hospitals are diagnosed with hypertension and experience an elevated blood pressure (BP) reading during hospitalization. There are no guidelines for managing asymptomatically elevated BPs in the inpatient setting, and growing observational evidence suggests that antihypertensive medication intensification increases harm. The proposed study tests whether a unit-based intervention (ACT-BP) can reduce antihypertensive medication intensification and provides information that is scientifically necessary for designing a cluster-randomized clinical trial that identifies the impact of intensification after experiencing an asymptomatically elevated BP on patient outcomes.",[92],"Blood Pressure Control",[94,95],"hypertension","inpatient","2026-01-06",{"date":98,"type":99},"2026-01-08","ACTUAL",{"date":101,"type":99},"2025-11-11",{"date":103,"type":86},"2027-07-31",{"name":54,"class":6},2]