[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100603272":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":25,"locations":34,"responsibleParty":57,"collaborators":10,"id":60,"slug":61,"hasResults":62,"nctId":63,"briefTitle":64,"officialTitle":65,"acronym":66,"eligibilityCriteria":67,"healthyVolunteers":62,"sex":68,"minAge":69,"maxAge":10,"enrollmentInfo":70,"targetDuration":10,"studyType":73,"phases":10,"briefSummary":74,"conditions":75,"keywords":78,"overallStatus":37,"whyStopped":10,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":91},{"fullName":5,"class":6},"University of Sao Paulo General Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Surgical Cohort",null,"Patients diagnosed with primary carpal tunnel syndrome (CTS) are undergoing open carpal tunnel release as part of their routine clinical care. The surgical procedure is not assigned by the study but performed according to standard practice. The cohort will be followed prospectively with clinical assessments (Boston Carpal Tunnel Questionnaire, QuickDASH, grip and pinch strength, Semmes-Weinstein monofilament testing), as well as ultrasonographic evaluation of the median nerve cross-sectional area, before and at three and six months after surgery, to identify prognostic factors associated with functional and symptomatic recovery.",[13],"Procedure: Open Carpal Tunnel Release",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":10},"PROCEDURE","Open Carpal Tunnel Release","All patients included in the cohort will undergo open carpal tunnel release as part of routine clinical care. The study does not assign the surgical procedure as an investigational intervention; however, it will observe clinical and ultrasonographic outcomes before and after surgery to assess prognostic factors.",[9],[21],{"name":22,"affiliation":23,"role":24},"Marcelo Rosa Rezende, MD, PhD,","HOSPITAL DAS CLÍNICAS DA FACULDADE DE MEDICINA DA UNIVERSIDADE DE SÃO PAULO (HCFM\u002FUSP)","PRINCIPAL_INVESTIGATOR",[26,31],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Joao Carlos Rodrigues, MD, PhD","CONTACT","+55112661-6909","joao.r@hc.fm.usp.br",{"name":32,"role":28,"phone":29,"phoneExt":10,"email":33},"Marcelo Rosa Rezende, MD, PhD","marcelo.rezende@ hc.fm.usp.br",[35],{"facility":36,"status":37,"city":38,"state":38,"zip":39,"country":40,"countryCode":41,"cosmosGeoPoint":42,"geoPoint":47,"contacts":48},"Instituto de Ortopedia e Traumatologia do Hospital das Clínicas da FMUSP","RECRUITING","São Paulo","05402-000","Brazil","BR",{"type":43,"coordinates":44},"Point",[45,46],-46.63611,-23.5475,{"lat":46,"lon":45},[49,52,54,55],{"name":32,"role":28,"phone":50,"phoneExt":10,"email":51},"+55 11 2661-6909","marcelo.rezende@hc.fm.usp.br",{"name":53,"role":28,"phone":50,"phoneExt":10,"email":30},"João Carlos Rodrigues, MD, PhD",{"name":32,"role":24,"phone":10,"phoneExt":10,"email":10},{"name":53,"role":56,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":24,"investigatorFullName":58,"investigatorTitle":59,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Marcelo Rosa de Rezende","MD, PHD","100603272","evaluation-by-clinical-and-hand-ultrasound-in-carpal-tunnel-syndrome-100603272",false,"NCT07134361","Evaluation by Clinical and Hand Ultrasound in Carpal Tunnel Syndrome","Clinical Analysis and Ultrasound Evaluation of the Median Nerve Cross-sectional Area Before and After Carpal Tunnel Release","ECHO-CTS","Inclusion Criteria:\n\n* Clinical diagnosis of primary carpal tunnel syndrome (CTS), confirmed by characteristic symptoms, physical examination findings, and a cross-sectional area superior to 10 mm² in the ultrasonography baseline.\n* Indication for open carpal tunnel release as part of routine clinical care.\n\nExclusion Criteria:\n\n* Secondary CTS due to inflammatory arthritis, prior wrist trauma, or space-occupying lesions.\n* History of previous carpal tunnel release in the affected hand.\n* Concomitant peripheral neuropathies (e.g., diabetic polyneuropathy) or cervical radiculopathy\n* Inability to undergo ultrasound assessment","ALL","18 Years",{"count":71,"type":72},106,"ESTIMATED","OBSERVATIONAL","Carpal Tunnel Syndrome (CTS) is a common condition where pressure on the median nerve in the wrist causes pain, numbness, and weakness in the hand. Surgery to release the carpal tunnel is often performed to relieve these symptoms.\n\nThis study will evaluate the changes in the median nerve after surgery and how these changes relate to symptom improvement. Investigators will use ultrasound imaging to measure the nerve size before and at three and six months after surgery. Patients will also complete questionnaires about their symptoms and hand function, and undergo tests to assess strength and sensation.\n\nThe investigator's goal is to determine whether changes observed on ultrasound are associated with the rate of patient recovery. This may help doctors better monitor healing and improve care for people with CTS.",[76,77],"Carpal Tunnel Syndrome (CTS)","Carpal Tunnel Surgery",[79,80,81],"carpal tunnel syndromes","Median Neuropathy","Ultrasonography","2025-08-21",{"date":84,"type":85},"2025-08-28","ACTUAL",{"date":87,"type":85},"2025-06-25",{"date":89,"type":72},"2028-12-31",{"name":5,"class":6},1]