[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100472449":3},{"organization":4,"armGroups":7,"interventions":22,"overallOfficials":28,"centralContacts":33,"locations":43,"responsibleParty":61,"collaborators":10,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":69,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":10,"enrollmentInfo":74,"targetDuration":10,"studyType":77,"phases":10,"briefSummary":78,"conditions":79,"keywords":10,"overallStatus":45,"whyStopped":10,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":90},{"fullName":5,"class":6},"R&D Cardiologie","OTHER",[8,14,18],{"label":9,"type":10,"description":11,"interventionNames":12},"Radiofrequency ablation, High power, short duration",null,"Radiofrequency ablation is an ablation modality that uses radiofrequency energy to create ablation lesions through heat. Patients that are scheduled for pulmonary vein isolation using radiofrequency ablation will be consented for study participation.",[13],"Device: Catheter ablation",{"label":15,"type":10,"description":16,"interventionNames":17},"Ultra-low temperature cryo ablation","Ultra-low temperature cryo ablation is an ablation modality that uses nitrogen near its liquid-vapor critical point to create ablation lesions through ultra-low temperatures. Patients that are scheduled for pulmonary vein isolation using ultra-low temperature cryo ablation will be consented for study participation.",[13],{"label":19,"type":10,"description":20,"interventionNames":21},"Pulsed field ablation","Pulsed field ablation is an ablation modality that uses short lived electrical fields to create ablation lesions through irreversible electroporation. Patients that are scheduled for pulmonary vein isolation using pulsed field ablation will be consented for study participation.",[13],[23],{"type":24,"name":25,"description":26,"armGroupLabels":27,"otherNames":10},"DEVICE","Catheter ablation","An ablation catheter is introduced in the heart. Ablation is performed by applying ablation energy to the target tissue. The aim of ablation is to create an ablation lesion that does not conduct the electrical signals that induce or sustain the cardiac arrhythmia.",[19,9,15],[29],{"name":30,"affiliation":31,"role":32},"Lucas VA Boersma, MD, PhD","St. Antonius Hospital","PRINCIPAL_INVESTIGATOR",[34,39],{"name":30,"role":35,"phone":36,"phoneExt":37,"email":38},"CONTACT","0883200900","+31","l.boersma@antoniusziekenhuis.nl",{"name":40,"role":35,"phone":41,"phoneExt":37,"email":42},"Bob GS Abeln, MD","0883201212","b.abeln@antoniusziekenhuis.nl",[44],{"facility":31,"status":45,"city":46,"state":10,"zip":47,"country":48,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"RECRUITING","Nieuwegein","3435 CM","Netherlands","NL",{"type":51,"coordinates":52},"Point",[53,54],5.08056,52.02917,{"lat":54,"lon":53},[57,58,59],{"name":40,"role":35,"phone":41,"phoneExt":37,"email":42},{"name":30,"role":32,"phone":10,"phoneExt":10,"email":10},{"name":40,"role":60,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":32,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"L.V.A. Boersma","Clinical professor","100472449","evaluation-of-ablation-lesions-using-cardiovascular-magnetic-resonance-imaging-100472449",false,"NCT05432024","Evaluation of Ablation Lesions Using Cardiovascular Magnetic Resonance Imaging","ENABLE-CMR","Inclusion Criteria:\n\n* Adult patients (age ≥18 years old)\n* Paroxysmal or persistent atrial fibrillation, meeting criteria of the 2020 European Society of Cardiology Guidelines for diagnosis and management of atrial fibrillation\n* Patients scheduled to undergo catheter ablation for cardiac arrhythmia using one of the following techniques: Radiofrequency ablation (High power, short duration), Ultra-low temperature cryo ablation, or Pulsed field ablation\n\nExclusion Criteria:\n\n* Known (or suspected) allergic reaction to gadolinium\n* Contraindications for MRI (such as claustrophobia, certain implants, devices, high body mass index).\n* Pregnancy or breastfeeding\n* Prior intervention in the left atrium (ablation or surgery)",true,"ALL","18 Years",{"count":75,"type":76},60,"ESTIMATED","OBSERVATIONAL","Ineffective ablation lesions can cause arrhythmia recurrence after catheter ablation for cardiac arrhythmia. Ablation lesions can be created with various ablation energy modalities. This study uses cardiovascular magnetic resonance imaging to evaluate the ablation lesion characteristics of radiofrequency ablation, ultra-low temperature cryo ablation, and pulsed field ablation. The ablation lesion characteristics of different energy characteristics will be compared. Additionally, arrhythmia recurrence and quality of life will be evaluated for the different energy modalities.",[80],"Atrial Fibrillation","2025-07-23",{"date":83,"type":84},"2025-07-28","ACTUAL",{"date":86,"type":84},"2023-03-08",{"date":88,"type":76},"2028-04-01",{"name":5,"class":6},1]