[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100272756":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":17,"locations":22,"responsibleParty":43,"collaborators":10,"id":45,"slug":46,"hasResults":47,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":10,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":10,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":25,"whyStopped":10,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":79},{"fullName":5,"class":6},"National Institutes of Health Clinical Center (CC)","NIH",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Adults with known or suspected endocrine or metabolic dissorde",null,"Adults with known or suspected endocrine or metabolic dissorders",[13],{"name":14,"affiliation":15,"role":16},"Marissa F Lightbourne, M.D.","National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)","PRINCIPAL_INVESTIGATOR",[18],{"name":14,"role":19,"phone":20,"phoneExt":10,"email":21},"CONTACT","(301) 827-0033","marissa.lightbourne@nih.gov",[23],{"facility":24,"status":25,"city":26,"state":27,"zip":28,"country":29,"countryCode":30,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"National Institutes of Health Clinical Center","RECRUITING","Bethesda","Maryland","20892","United States","US",{"type":32,"coordinates":33},"Point",[34,35],-77.10026,38.98067,{"lat":35,"lon":34},[38],{"name":39,"role":19,"phone":40,"phoneExt":41,"email":42},"For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)","800-411-1222","TTY8664111010","prpl@cc.nih.gov",{"type":44,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR","100272756","evaluation-of-adults-with-endocrine-and-metabolic-related-conditions-100272756",false,"NCT02830308","Evaluation of Adults With Endocrine and Metabolic-Related Conditions","Evaluation of Adults With Endocrine-Related Conditions","* INCLUSION CRITERIA:\n* Participants with known or suspected endocrine disorder age 18 years and older are eligible for this protocol. Protocol investigators will make the actual selection of subjects most appropriate for clinical evaluation.\n* Relatives ages 18 years and older may be enrolled if clinically indicated for the diagnosis of a proband.\n\nEXCLUSION CRITERIA:\n\n* Anyone under the age of 18 years old\n* Any medical, physical, psychiatric, or social conditions, which, in the opinion of the investigators, would make participation in this protocol not in the best interest of the subject. Subjects who are critically ill, unstable, or with severe organ failure that may affect\u002Flimit the endocrine evaluation and place unsustainable demands on Clinical Center or NIDDK resources.",true,"ALL","18 Years","100 Years",{"count":57,"type":58},1250,"ESTIMATED","OBSERVATIONAL","Background:\n\nThere are many endocrine and metabolic-related conditions. Two well-known disorders include diabetes and thyroid disease. Some of these diseases are caused by a change in genes. Researchers want to identify the genes involved in these disorders. They hope this will help them learn more about these diseases.\n\nObjectives:\n\nTo learn more about conditions that affect the hormone-secreting glands (endocrine glands) in adults. To train doctors to diagnose and treat people with endocrine or metabolic conditions.\n\nEligibility:\n\nAdults age 18 years and older with a known or suspected endocrine disorder.\n\nRelatives ages 18 years and older.\n\nDoctors will review all requests and available medical records to determine final eligibility for the protocol.\n\nDesign:\n\nParticipants will have a medical history and physical exam.\n\nMost participants will have 1 visit, and may have follow up visits if necessary. They may have tests, surgery, or other procedures to help diagnose or treat their condition. These could include:\n\n* Blood, urine, and saliva tests\n* Imaging tests. These may include X-ray, ultrasound, or scans.\n* Sleep study\n* Medical photographs\n* Visits with other specialists at NIH\n\nParticipants will provide blood, urine, saliva, or tissue samples. Some of these samples may be stored in the freezer for future studies.\n\nParticipants may be asked to participate in genetic testing. They will give a blood or saliva sample for this.",[62],"Endocrine Diseases",[64,65,66,67,68,69],"Hormones","Endocrine","Hypercortisolism","Bone","Hypothalamic-Pituitary Dysfunction","Natural History","2026-05-09",{"date":72,"type":73},"2026-05-12","ACTUAL",{"date":75,"type":73},"2016-07-09",{"date":77,"type":58},"2029-12-31",{"name":15,"class":6},1]