[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100554684":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":27,"centralContacts":31,"locations":40,"responsibleParty":53,"collaborators":18,"id":56,"slug":57,"hasResults":58,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":18,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":64,"minAge":65,"maxAge":66,"enrollmentInfo":67,"targetDuration":18,"studyType":70,"phases":71,"briefSummary":73,"conditions":74,"keywords":76,"overallStatus":78,"whyStopped":18,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":88},{"fullName":5,"class":6},"Chittagong Medical College","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Intervention Group-A: Administration of a specific antibiotic regimen post-extraction.","EXPERIMENTAL","Patients will be prescribed 625 mg of amoxicillin with combined clavulanic acid tablets three times a day after meals for 7 days following extraction and also a non-steroidal anti-inflammatory drug, 400 mg ibuprofen, and an H2 receptor blocker, 20 mg omeprazole, twice daily before meals.",[13],"Drug: 625 mg of amoxicillin with combined clavulanic acid tablet",{"label":15,"type":16,"description":17,"interventionNames":18},"Control Group-B: Administration of no antibiotic.","NO_INTERVENTION","No post-operative antibiotics will be administered, patients will be prescribed a non-steroidal anti-inflammatory drug, 400 mg ibuprofen, and an H2 receptor blocker, 20 mg omeprazole, twice daily before meals.",null,[20],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DRUG","625 mg of amoxicillin with combined clavulanic acid tablet","The intervention group must take 625 mg of amoxicillin with combined clavulanic acid tablets three times a day after meals for 7 days following extraction.",[9],[26],"Tablet. Bioclavid 625 mg",[28],{"name":29,"affiliation":5,"role":30},"Md Salim Uddin, BDS, MPhil","PRINCIPAL_INVESTIGATOR",[32,36],{"name":29,"role":33,"phone":34,"phoneExt":18,"email":35},"CONTACT","+8801817754980","salim.bdscmc@gmail.com",{"name":37,"role":33,"phone":38,"phoneExt":18,"email":39},"Manjur-E -Mahmud, BDS,FCPS","+8801716-409228","manjuddc36@gmail.com",[41],{"facility":5,"status":18,"city":42,"state":18,"zip":18,"country":43,"countryCode":44,"cosmosGeoPoint":45,"geoPoint":50,"contacts":51},"Chittagong","Bangladesh","BD",{"type":46,"coordinates":47},"Point",[48,49],91.83168,22.3384,{"lat":49,"lon":48},[52],{"name":29,"role":33,"phone":18,"phoneExt":18,"email":18},{"type":30,"investigatorFullName":54,"investigatorTitle":55,"investigatorAffiliation":5,"oldNameTitle":18,"oldOrganization":18},"Salim Uddin","Lecturer, Children Dentistry","100554684","evaluation-of-antibiotic-administration-following-tooth-extraction-100554684",false,"NCT06502288","Evaluation of Antibiotic Administration Following Tooth Extraction","Evaluation of Necessity of Antibiotic Administration Following Tooth Extraction: A Randomized Control Trial","Inclusion Criteria:\n\n1. Patient indicated extraction of teeth\n2. Provide informed written consent\n3. Patients aged between 18 to 50 years\n\nExclusion Criteria:\n\n1. The tooth with abscess, infected cyst and tumors that require extensive surgery including impacted teeth\n2. Patients who have taken antibiotics before 5 days for any reason will be excluded\n3. Patients who are medically compromised such as DM, Congenital cyanotic heart disease, chronic kidney disease (CKD), Patients with chemotherapy or radiotherapy, Chronic Liver Disease (CLD), etc.\n4. Female patients who are pregnant or lactating\n5. Those women during the menstruation period (disturbed fibrinolytic activity),\n6. Participants who are known hypersensitive to the given drugs used in this study\n7. Participants who have known resistance to intervention drugs",true,"ALL","18 Years","50 Years",{"count":68,"type":69},152,"ESTIMATED","INTERVENTIONAL",[72],"NA","The trial aims to evaluate the effects of prescribing antibiotics after tooth extraction. 152 dental patients aged 18 to 50 will be randomly assigned. The study will assess infection rates, healing times, pain, and adverse effects in patients who receive antibiotics versus those who do not. The trial will be conducted at the Oral and Maxillofacial Surgery Department, Dental Unit, Chittagong Medical College. Data analysis will involve the use of the χ²-test, t-tests, and logistic regression, with a significance level of 5%. Ethical considerations include obtaining informed consent from all participants, and safety will be monitored by an independent expert team.",[75],"Tooth Extraction",[77],"Antibiotic, tooth extraction, RCT","NOT_YET_RECRUITING","2024-07-13",{"date":81,"type":82},"2024-07-16","ACTUAL",{"date":84,"type":69},"2025-01-01",{"date":86,"type":69},"2025-10-15",{"name":5,"class":6},1]