[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100629290":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":30,"centralContacts":34,"locations":43,"responsibleParty":58,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":25,"eligibilityCriteria":68,"healthyVolunteers":64,"sex":69,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":81,"overallStatus":89,"whyStopped":25,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":94,"completionDateStruct":96,"leadSponsor":98,"locationsCount":99},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Rotary Instrumentation Group","EXPERIMENTAL","Single Rotary File System",[13],"Procedure: Rotary Instrumentation",{"label":15,"type":10,"description":16,"interventionNames":17},"Manual Instrumentation Group","Manual Stainless Steel K-File Instrumentation",[18],"Procedure: Manual Instrumentation",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","Rotary Instrumentation","After opening the access cavity, the root canal patency will be checked for all the canals located using a size #15 (0.02%) K file, then a single rotary file (AF F One, FANTA, China) (20 taper 4) will be adjusted to the desirable working length depending on an electronic apex locator (1 mm shorter than the apex). This file will be used in the pulpectomy procedure using a brushing motion and will be irrigated with saline.",[9],null,{"type":21,"name":27,"description":28,"armGroupLabels":29,"otherNames":25},"Manual Instrumentation","After opening the access cavity, manual files (K files, Mani, Inc., Japan) of sizes 15, 20, 25, and 30 will be adjusted to the desirable working length depending on an electronic apex locator (1 mm shorter than the apex). These files will be used in the pulpectomy procedure using a brushing motion and will be irrigated with saline.",[15],[31],{"name":32,"affiliation":5,"role":33},"Gihan M Abu elniel, professor","STUDY_DIRECTOR",[35,40],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},"Aya G Abd elzaher, master","CONTACT","+01100480444","aya_gamal@dentistry.cu.edu.eg",{"name":41,"role":37,"phone":25,"phoneExt":25,"email":42},"Hanaa A Abd el moniem","hanaa.ibraheem@dentistry.cu.edu.eg",[44],{"facility":45,"status":25,"city":46,"state":47,"zip":48,"country":47,"countryCode":49,"cosmosGeoPoint":50,"geoPoint":55,"contacts":56},"Faculty of dentistry, Cairo university","Cairo","Egypt","11411","EG",{"type":51,"coordinates":52},"Point",[53,54],31.24967,30.06263,{"lat":54,"lon":53},[57],{"name":36,"role":37,"phone":38,"phoneExt":25,"email":39},{"type":59,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Aya Gamal Abd Elzaher","candidate in department of pediatric dentistry and dental public health department, faculty of dentistry, Cairo university","100629290","evaluation-of-bacterial-reduction-after-pulpectomy-in-primary-molars-100629290",false,"NCT07472751","Evaluation of Bacterial Reduction After Pulpectomy in Primary Molars","Comparative Evaluation of Bacterial Reduction Using Single Rotary File System Versus Manual Instrumentation in Pulpectomy of Primary Molars: An In Vitro and In Vivo Study","Inclusion Criteria:\n\n* Children age 4 to 6 years\n* Medically free children\n* Cooperative children\n* Restorable mandibular second primary molars with signs or symptoms of irreversible pulpitis\n* No internal root resorption on radiograph\n* No external root resorption on radiograph\n* No periapical radiolucency\n* No inter-radicular radiolucency\n\nExclusion Criteria:\n\n* Uncooperative children\n* Children with systemic disease\n* Children with physical disability\n* Children with mental disability\n* Refusal to participate\n* Inability to attend follow-up visits\n* Refusal to sign consent form\n* Previously accessed teeth\n* Mobile mandibular primary molars\n* Pain on percussion\n* Swelling on palpation or in the vestibule","ALL","4 Years","6 Years",{"count":73,"type":74},34,"ESTIMATED","INTERVENTIONAL",[77],"NA","The primary aim of the study is to compare the bacterial reduction in pulpectomy of primary molars using a single rotary file system versus conventional manual instrumentation.",[80],"Irreversible Pulpitis",[82,83,84,85,86,87,88],"Pediatric endodontics","Intracanal bacterial reduction","Endodontic treatment in children","Chemo-mechanical preparation","Pulpectomy","primary molars","Bacterial load reduction","NOT_YET_RECRUITING","2026-03-13",{"date":92,"type":93},"2026-03-17","ACTUAL",{"date":95,"type":74},"2026-04",{"date":97,"type":74},"2027-10",{"name":5,"class":6},1]