[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100640568":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":11,"centralContacts":29,"locations":11,"responsibleParty":38,"collaborators":11,"id":40,"slug":41,"hasResults":42,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":42,"sex":48,"minAge":49,"maxAge":11,"enrollmentInfo":50,"targetDuration":11,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":59,"overallStatus":67,"whyStopped":11,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":11},{"fullName":5,"class":6},"Instituto de Investigación Marqués de Valdecilla","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"carotid artery stenting with proximal embolic protection using a balloon guide catheter","EXPERIMENTAL",null,[13],"Device: balloon guide catheter",{"label":15,"type":16,"description":11,"interventionNames":17},"ratio to carotid artery stenting without proximal embolic protection using a balloon guide catheter.","ACTIVE_COMPARATOR",[18],"Other: No Proximal Protection Group",[20,25],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":11},"DEVICE","balloon guide catheter","Carotid artery stenting with proximal embolic protection using a balloon guide catheter.",[9],{"type":6,"name":26,"description":27,"armGroupLabels":28,"otherNames":11},"No Proximal Protection Group","Carotid artery stenting without proximal embolic protection",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":11,"email":34},"veronica vidal","CONTACT","942203389","veronica.vidal@idival.org",{"name":36,"role":32,"phone":11,"phoneExt":11,"email":37},"lucia lavin","lucia.lavin@idival.org",{"type":39,"investigatorFullName":11,"investigatorTitle":11,"investigatorAffiliation":11,"oldNameTitle":11,"oldOrganization":11},"SPONSOR","100640568","evaluation-of-balloon-guide-catheter-as-proximal-protection-during-carotid-artery-stenting-embo-protect-100640568",false,"NCT07576790","Evaluation of Balloon Guide Catheter as Proximal Protection During Carotid Artery Stenting (EMBO-PROTECT)","Evaluation of Balloon Guide Catheter as Proximal Protection During Carotid Artery Stenting: A Randomized Study (EMBO-PROTECT)","EMBO-PROTECT","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Symptomatic or asymptomatic carotid artery stenosis\n* Candidate for carotid artery stenting\n* Written informed consent provided\n\nExclusion Criteria:\n\n* Vascular anatomy unsuitable for balloon guide catheter placement\n* Severe renal failure\n* Previous disabling stroke or symptomatic intracranial hemorrhage\n* Evidence of carotid thrombus\n* Severe common carotid artery lesion\n* Chronic atrial fibrillation on oral anticoagulation\n* Acute coronary syndrome within 30 days\n* Contraindications to anticoagulant or antiplatelet therapy\n* Contraindications to MRI\n* Contrast media allergy\n* Lack of prior dual antiplatelet therapy","ALL","18 Years",{"count":51,"type":52},126,"ESTIMATED","INTERVENTIONAL",[55],"NA","Carotid angioplasty and stenting (CAS) is an effective treatment for carotid artery stenosis but carries a risk of cerebral embolization. This prospective randomized study evaluates the safety and efficacy of proximal embolic protection using a balloon guide catheter during CAS by comparing the incidence of diffusion-weighted MRI-detected microembolisms and symptomatic thromboembolic events between protected and unprotected procedures.",[58],"Carotid Artery Stenosis (Symptomatic and Asymptomatic)",[60,61,62,63,64,65,66],"Carotid stenosis","Carotid artery stenting","Balloon guide catheter","Proximal embolic protection","Cerebral microembolism","Diffusion-weighted MRI","Stroke prevention","NOT_YET_RECRUITING","2026-05-04",{"date":70,"type":71},"2026-05-08","ACTUAL",{"date":73,"type":52},"2026-07-01",{"date":75,"type":52},"2027-12-31",{"name":5,"class":6}]