[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100559090":3},{"organization":4,"armGroups":7,"interventions":20,"overallOfficials":31,"centralContacts":35,"locations":44,"responsibleParty":60,"collaborators":30,"id":64,"slug":65,"hasResults":66,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":30,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":72,"minAge":73,"maxAge":74,"enrollmentInfo":75,"targetDuration":30,"studyType":78,"phases":79,"briefSummary":81,"conditions":82,"keywords":84,"overallStatus":47,"whyStopped":30,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":96},{"fullName":5,"class":6},"Cairo University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"zirconia barrier","ACTIVE_COMPARATOR","Zirconia will be used as a barrier material because it has interesting features and, if compared to titanium, it induces a better fibroblast response. It also shows less biofilm adhesion and less inflammatory response. From the pre-operative CBCT a 3D model of the alveolar jaw bone will be created. A 0.4-0.5 mm-thick barrier will then be designed. It will be designed to cover the planned bone graft and extended a few millimeters wider than the graft perimeter.",[13],"Procedure: zirconia barrier",{"label":15,"type":16,"description":17,"interventionNames":18},"titanium mesh","PLACEBO_COMPARATOR","Titanium mesh in particular, its clinical suitability for GBR procedures is unmatched by other GBR membranes, due to their exceptional volume stability, titanium meshes are indispensable in the management of vertical or large horizontal bone defects. Titanium meshes not only demonstrate high strength and stiffness but also exhibit good plasticity, allowing them to be perfectly adapted to various bone defects through bending and shaping. Due to titanium mesh's stiffness and sharp edges from cutting and bending, mucosal flaps may be adversely stimulated, leading to mucosal rupture and subsequent mesh exposure",[19],"Procedure: titanium mesh",[21,27],{"type":22,"name":9,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","barrier membrane used for guided bone regeneration and augmentation of ridge defect",[9],[26],"zirconia membrane",{"type":22,"name":15,"description":28,"armGroupLabels":29,"otherNames":30},"barrier membrane used for guided bone regeneration",[15],null,[32],{"name":33,"affiliation":5,"role":34},"Hani El Nahass","STUDY_DIRECTOR",[36,41],{"name":37,"role":38,"phone":39,"phoneExt":30,"email":40},"Amaal Abdalnassar abdalzeim","CONTACT","01003752752","amaalabdalnassar@gmail.com",{"name":42,"role":38,"phone":30,"phoneExt":30,"email":43},"Omnia Khaled Tawfik","omnia.tawfik@dentistry.cu.edu.eg",[45],{"facility":46,"status":47,"city":48,"state":30,"zip":30,"country":49,"countryCode":50,"cosmosGeoPoint":51,"geoPoint":56,"contacts":57},"Cairo university","RECRUITING","Cairo","Egypt","EG",{"type":52,"coordinates":53},"Point",[54,55],31.24967,30.06263,{"lat":55,"lon":54},[58],{"name":59,"role":38,"phone":39,"phoneExt":30,"email":40},"Amaal Abdalnassar Abdalzeim",{"type":61,"investigatorFullName":62,"investigatorTitle":63,"investigatorAffiliation":5,"oldNameTitle":30,"oldOrganization":30},"PRINCIPAL_INVESTIGATOR","Amaal Abdel Nasser Said Mohamed","Principal Investigator","100559090","evaluation-of-bone-gain-using-customized-3d-zirconia-barrier-versus-titanium-mesh-100559090",false,"NCT06559605","Evaluation of Bone Gain Using Customized 3D Zirconia Barrier Versus Titanium Mesh","Clinical and Radiographic Evaluation of Bone Gain Using Customized 3D Printed Zirconia Barrier Versus Titanium Mesh in Combined Ridge Defects in The Aesthetic Zone: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Age: 20-70 years.\n* Bone width less than 4mm\n* Vertical bone height less than 9mm\n* Periodontally sound neighboring teeth\n* Patients with sound vertical occlusal bite dimension\n* Good oral hygiene (full mouth plaque control record \\[PCR\\] \\\u003C 25%,full mouth bleeding on probing (BOP) \\\u003C 25% .\n* Patients demonstrating understanding and commitment to the post-operative care regime and the study follow up timeline.\n* Good general health (including participants with well-controlled systemic disease)\n\nExclusion Criteria:\n\n1. Pathological lesions (abscess-cyst-acute infection) in the defect site\n2. Systemic diseases that would interfere with bone metabolism\n3. Uncontrolled diabetic patients\n4. Ongoing treatment or a history of recent chemotherapy or radiotherapy\n5. Poor oral hygiene after hygienic phase (Plaque control record over 30%) or Active periodontal disease",true,"ALL","20 Years","70 Years",{"count":76,"type":77},26,"ESTIMATED","INTERVENTIONAL",[80],"NA","Evaluation of clinical and radiographical amount of bone gained using customized 3D printed zirconia barrier compared to titanium mesh in combined ridge defect at the esthetic zone.",[83],"Bone Loss, Alveolar",[26,85,86],"titanium membrane","combined bone defect","2024-08-16",{"date":89,"type":90},"2024-08-20","ACTUAL",{"date":92,"type":90},"2024-05-22",{"date":94,"type":77},"2026-11-22",{"name":5,"class":6},1]