[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100617333":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":12,"centralContacts":19,"locations":27,"responsibleParty":43,"collaborators":10,"id":46,"slug":47,"hasResults":48,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":10,"eligibilityCriteria":51,"healthyVolunteers":48,"sex":52,"minAge":53,"maxAge":54,"enrollmentInfo":55,"targetDuration":58,"studyType":59,"phases":10,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":73,"whyStopped":10,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Akdeniz University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients Robotic Prostate Surgery",null,"Men aged 18 to 80 undergoing robotic prostate surgery",[13,16],{"name":14,"affiliation":5,"role":15},"Hanife Kabukcu","STUDY_DIRECTOR",{"name":17,"affiliation":5,"role":18},"Sinem Omca","PRINCIPAL_INVESTIGATOR",[20,24],{"name":14,"role":21,"phone":22,"phoneExt":10,"email":23},"CONTACT","+905337319555","hanifekabukcu@akdeniz.edu.tr",{"name":17,"role":21,"phone":25,"phoneExt":10,"email":26},"+905061187398","snmomca@gmail.com",[28],{"facility":5,"status":10,"city":29,"state":29,"zip":10,"country":30,"countryCode":10,"cosmosGeoPoint":31,"geoPoint":36,"contacts":37},"Antalya","Turkey (Türkiye)",{"type":32,"coordinates":33},"Point",[34,35],30.69556,36.90812,{"lat":35,"lon":34},[38,39,40,41],{"name":17,"role":21,"phone":25,"phoneExt":10,"email":26},{"name":14,"role":21,"phone":22,"phoneExt":10,"email":23},{"name":17,"role":18,"phone":10,"phoneExt":10,"email":10},{"name":14,"role":42,"phone":10,"phoneExt":10,"email":10},"SUB_INVESTIGATOR",{"type":44,"investigatorFullName":14,"investigatorTitle":45,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"SPONSOR_INVESTIGATOR","Prof. Dr.","100617333","evaluation-of-cerebral-perfusion-in-supine-and-steep-trendelenburg-positions-during-robotic-prostatectomy-100617333",false,"NCT07317258","Evaluation of Cerebral Perfusion in Supine and Steep Trendelenburg Positions During Robotic Prostatectomy","Inclusion Criteria:\n\nMale patients aged 18 to 80 years\n\nASA physical status I-III\n\nScheduled for robotic prostate surgery under general anesthesia\n\nAble and willing to provide written informed consent\n\nExclusion Criteria:\n\nDecline or inability to provide informed consent\n\nAge \\\u003C18 years or \\>80 years\n\nInability to perform ultrasonographic measurements or to maintain the required surgical position\n\nPresence of intracranial space-occupying lesions\n\nHistory of cerebrovascular accident (CVA) or carotid artery occlusion\n\nKnown neurological disorders (e.g., epilepsy)","MALE","18 Years","80 Years",{"count":56,"type":57},60,"ESTIMATED","1 Day","OBSERVATIONAL","Evaluation of Cerebral Perfusion in Supine and Steep Trendelenburg Positions During Robotic Prostatectomy Robotic endoscopic radical prostatectomy requires pneumoperitoneum and the steep Trendelenburg position to ensure optimal surgical visualization. However, this combination may increase intracranial pressure (ICP) and alter cerebral blood flow and oxygenation.\n\nThis study aimed to evaluate cerebral perfusion changes in patients undergoing robotic prostatectomy by using Transcranial Doppler (TCD) and Near-Infrared Spectroscopy (NIRS). Cerebral blood flow velocity in the middle cerebral artery and pulsatility index (PI) were measured to estimate ICP, while NIRS was used to assess cerebral oxygen saturation.\n\nAdditionally, arterial blood gas parameters (PCO₂, PO₂, Hb), end-tidal CO₂, and mean arterial pressure (MAP) were recorded. Pre- and postoperative Mini-Mental State Examination (MMSE) scores were compared to evaluate potential cognitive effects.\n\nThe aim was to determine the relationship between ICP estimation, cerebral oxygenation, and hemodynamic variables during supine and steep Trendelenburg positions in robotic prostatectomy.",[62,63],"Cerebral Perfusion Pressure","Trendelenburg",[65,66,67,68,69,70,71,72],"TRANSCRANİAL DOPPLER USG","CEREBRAL PERFUSİON","TRENDELENBURG","NIRS","EEG","PATİENT STATE İNDEKS","ROBOTİC SURGERY","PROSTATEKTOMİ","NOT_YET_RECRUITING","2025-12-24",{"date":76,"type":77},"2026-01-05","ACTUAL",{"date":79,"type":57},"2026-01-01",{"date":81,"type":57},"2026-11",{"name":14,"class":6},1]