[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100627711":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":21,"centralContacts":25,"locations":10,"responsibleParty":31,"collaborators":10,"id":34,"slug":35,"hasResults":36,"nctId":37,"briefTitle":38,"officialTitle":39,"acronym":10,"eligibilityCriteria":40,"healthyVolunteers":36,"sex":41,"minAge":10,"maxAge":10,"enrollmentInfo":42,"targetDuration":45,"studyType":46,"phases":10,"briefSummary":47,"conditions":48,"keywords":52,"overallStatus":59,"whyStopped":10,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":64,"completionDateStruct":65,"leadSponsor":67,"locationsCount":10},{"fullName":5,"class":6},"Sohag University","OTHER",[8,12,15,18],{"label":9,"type":10,"description":11,"interventionNames":10},"PAS patients with cervical invasion",null,"Have cervical invasion using criteria compiled from multiple studies: ٭Extension of placental tissue into the cervical stroma or cervico-isthmic complex (CIC), with placental tissue encroaching on or beyond the internal os without clear separation . ٭Irregular cervical contour or disruption of the normal cervical architecture, including fibrosis in the lower posterior cervical-trigonal space (associated with type 4 PAS and higher morbidity) . ٭Increased vascularity within the cervical canal or stroma, detected via color Doppler showing turbulent flow or lacunae extending into the cervix (predictive of deep invasion and bleeding risk) . ٭Presence of intracervical lakes (novel marker: hypoechoic or anechoic spaces within the cervical tissue, suggestive of invasive placentation) .",{"label":13,"type":10,"description":14,"interventionNames":10},"PAS patients without cervical invasion","Haven't cervical invasion using criteria compiled from multiple studies: ٭Extension of placental tissue into the cervical stroma or cervico-isthmic complex (CIC), with placental tissue encroaching on or beyond the internal os without clear separation . ٭Irregular cervical contour or disruption of the normal cervical architecture, including fibrosis in the lower posterior cervical-trigonal space (associated with type 4 PAS and higher morbidity) . ٭Increased vascularity within the cervical canal or stroma, detected via color Doppler showing turbulent flow or lacunae extending into the cervix (predictive of deep invasion and bleeding risk) . ٭Presence of intracervical lakes (novel marker: hypoechoic or anechoic spaces within the cervical tissue, suggestive of invasive placentation) . Scoring systems integration:",{"label":16,"type":10,"description":17,"interventionNames":10},"PAS patients with short cervical length","Cervical length will be measured in admission and before delivery The final CL measurement prior to delivery was analyzed. Unscheduled delivery was defined as urgent delivery prior to the scheduled date due to either bleeding or preterm contractions. A receiver operating characteristics (ROC) curve was created, the optimal CL associated with unscheduled delivery was selected, and associations and prediction analyses were performed. Short cl \\\u003C 3 cm",{"label":19,"type":10,"description":20,"interventionNames":10},"PAS patients with normal cervical length","Cervical length will be measured in admission and before delivery The final CL measurement prior to delivery was analyzed. Unscheduled delivery was defined as urgent delivery prior to the scheduled date due to either bleeding or preterm contractions. A receiver operating characteristics (ROC) curve was created, the optimal CL associated with unscheduled delivery was selected, and associations and prediction analyses were performed. Short cl ≥ 3 cm",[22],{"name":23,"affiliation":5,"role":24},"Ahmed Salah Ali, MSC","PRINCIPAL_INVESTIGATOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":10,"email":30},"Ahmed Salah Salah Ali, Assistant lecturer","CONTACT","+201050199550","ahmedsalahali37@yahoo.com",{"type":24,"investigatorFullName":32,"investigatorTitle":33,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"Ahmed Salah Ali","Assistant lecturer of OB.&GYN. ,Sohag faculty of medicine","100627711","evaluation-of-cervical-invasion-and-length-in-placenta-accreta-patients-100627711",false,"NCT07452185","Evaluation of Cervical Invasion and Length in Placenta Accreta Patients","Evaluation of Placental Cervical Invasion and Cervical Length in Patients With Placenta Accreta","Inclusion Criteria:\n\n* Pregnant women aged 18-45 years with suspected or confirmed PAS based on prenatal ultrasound (e.g., placenta previa with at least one prior cesarean section).\n* Gestational age between 18-32 weeks at enrollment to allow for serial monitoring.\n* Singleton pregnancy.\n* High-risk features such as history of multiple cesarean sections, antepartum bleeding, or abnormal placental location on initial screening.\n\nExclusion Criteria:\n\n* Multiple gestation.\n* Pre-existing cervical incompetence or cerclage placement prior to enrollment. -Transfer from outside facilities without complete prenatal records.","FEMALE",{"count":43,"type":44},200,"ESTIMATED","16 Weeks","OBSERVATIONAL","Placenta accreta spectrum (PAS), also called morbidly adherent placenta, is a serious pregnancy problem where the placenta attaches too deeply to the uterus wall and does not come out normally after birth. This often happens after previous cesarean sections or when the placenta is low (placenta previa). It can cause heavy bleeding, serious complications, and danger to the mother.\n\nThis study will look at pregnant women with PAS at Sohag University Hospital in Egypt. Researchers will use ultrasound to check two things:\n\nHow much the placenta has invaded the cervix (the lower part of the uterus). The length of the cervix.\n\nThe main goals are to find out:\n\nHow common cervical invasion is in PAS cases. What happens to women who have this invasion (outcomes like bleeding or surgery needs).\n\nIf a short cervix is linked to early labor (preterm birth). Women with confirmed PAS will join this observational study from March 2026 to January 2028. They will have extra ultrasound scans during pregnancy. No new treatments or drugs are tested - the study only collects information from routine care and scans to better understand the condition.\n\nThis research may help doctors predict risks earlier, plan safer deliveries, and improve care for mothers and babies with PAS in the future.",[49,50,51],"Placenta Accreta Spectrum","Placenta Accreta","Placenta Previa",[53,54,55,56,57,58],"Placenta accreta spectrum","Cervical invasion","Cervical length","Placenta accreta","Ultrasound evaluation","Preterm labor","NOT_YET_RECRUITING","2026-03-01",{"date":62,"type":63},"2026-03-05","ACTUAL",{"date":60,"type":44},{"date":66,"type":44},"2028-01-01",{"name":5,"class":6}]