[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100574316":3},{"organization":4,"armGroups":7,"interventions":8,"overallOfficials":7,"centralContacts":14,"locations":20,"responsibleParty":40,"collaborators":44,"id":47,"slug":48,"hasResults":49,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":7,"eligibilityCriteria":52,"healthyVolunteers":53,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":7,"targetDuration":7,"studyType":57,"phases":7,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":23,"whyStopped":7,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":7,"completionDateStruct":7,"leadSponsor":69,"locationsCount":70},{"fullName":5,"class":6},"Kocaeli University","OTHER",null,[9,12],{"type":6,"name":10,"description":11,"armGroupLabels":7,"otherNames":7},"Walking","Participants will perform 30 minutes of walking and cycling exercises. During the cycling and walking exercises, heart rate will be calculated using the Karvonen formula based on heart rate reserve.\n\nHRmax (maximum heart rate)=220-age HRR (%)(heart rate reserve)= (HR-HRrest)\u002F(HRmax-HRrest)\\*100\n\nBlood samples will be collected from participants before starting the exercise, at the end of the 30-minute exercise session, and twice more at 30-minute intervals. The same participants will perform the cycling exercise half an hour later, and the same procedures will be applied.",{"type":6,"name":13,"description":13,"armGroupLabels":7,"otherNames":7},"Cycling",[15],{"name":16,"role":17,"phone":18,"phoneExt":7,"email":19},"Oguzhan Demir","CONTACT","+90264 616 1614","oguzhandemir@subu.edu.tr",[21,32],{"facility":22,"status":23,"city":24,"state":7,"zip":7,"country":25,"countryCode":7,"cosmosGeoPoint":26,"geoPoint":31,"contacts":7},"Kocaeli University Faculty of Medicine Hospital","AVAILABLE","Kocaeli","Turkey (Türkiye)",{"type":27,"coordinates":28},"Point",[29,30],27.51145,39.62497,{"lat":30,"lon":29},{"facility":33,"status":23,"city":34,"state":7,"zip":7,"country":25,"countryCode":7,"cosmosGeoPoint":35,"geoPoint":39,"contacts":7},"Sakarya University Applied Sciences Physiotherapy and Rehabilitation Application and Research Center","Sakarya",{"type":27,"coordinates":36},[37,38],32.07583,39.50333,{"lat":38,"lon":37},{"type":41,"investigatorFullName":42,"investigatorTitle":43,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","Oguzhan Bahadir DEMIR","Assistant Professor",[45],{"name":46,"class":6},"Sakarya Applied Sciences University","100574316","evaluation-of-different-serum-cartilage-biomarkers-in-the-acute-response-to-walking-and-cycling-in-healthy-male-subjects-100574316",false,"NCT06757699","Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects","Inclusion Criteria:\n\n* Healthy male volunteers between the ages of 20-35\n* Those who do physical activity for at least 30 minutes two to three days a week\n* 17 healthy male individuals without any health problems will be included.\n\nExclusion Criteria:\n\n* Those with acute or chronic injuries in their lower extremities\n* Those with musculoskeletal disorders in their lower extremities\n* Those who have undergone hip and\u002For knee surgery\n* Those with cardio-pulmonary problems that prevent them from exercising",true,"MALE","20 Years","35 Years","EXPANDED_ACCESS","The effect of physical activity on serum cartilage biomarkers is largely unknown. This study is critical to increase our knowledge of the physiological cartilage response to activities of daily living and dynamic tasks by focusing on healthy recreationally active individuals, thus improving our understanding of the complex relationship between cartilage health and the loading that occurs during different types of loading.",[60],"Biochemical Markers",[62,63,64],"serum cartilage","Osteoblastic activity","Osteoclastic activity","2026-06-08",{"date":67,"type":68},"2026-06-10","ACTUAL",{"name":5,"class":6},2]