[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100578325":3},{"organization":4,"armGroups":7,"interventions":18,"overallOfficials":11,"centralContacts":11,"locations":24,"responsibleParty":38,"collaborators":11,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":11,"eligibilityCriteria":48,"healthyVolunteers":44,"sex":49,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":11,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":27,"whyStopped":11,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":73},{"fullName":5,"class":6},"Kafrelsheikh University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"immediate implant placement with doxycycline loaded gelatin nano particles and gelatin sponge","EXPERIMENTAL",null,[13],"Procedure: Immediate Implant Placement",{"label":15,"type":16,"description":11,"interventionNames":17},"Immediate Implant Placement with Doxycyline and Gelatin Sponge","ACTIVE_COMPARATOR",[13],[19],{"type":20,"name":21,"description":22,"armGroupLabels":23,"otherNames":11},"PROCEDURE","Immediate Implant Placement","Eight patients undergoing immediate implant placement with the buccal gap filled with doxycycline loaded gelatin nanoparticles along with gelatin sponge (group A) Eight patients undergoing immediate implant placement with the buccal gap filled with doxycycline along with gelatin sponge (group B)",[15,9],[25],{"facility":26,"status":27,"city":28,"state":28,"zip":29,"country":30,"countryCode":31,"cosmosGeoPoint":11,"geoPoint":11,"contacts":32},"Faculty of dentistry kafrelsheikh university","RECRUITING","Kafrelsheikh","12345","Egypt","EG",[33],{"name":34,"role":35,"phone":36,"phoneExt":11,"email":37},"Enas Ahmed Elgendy, Professor","CONTACT","+201003508797","Dentist@den.kfs.edu.eg",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Ahmed Othman Fathy Othman El-Kersh","demonstrator of Department of Periodontology, Oral Diagnosis and Oral Radiology at Faculty of Dentistry, Kafrelsheikh university","100578325","evaluation-of-doxycycline-nanoparticle-with-gelatin-sponge-on-immediate-implant-in-esthetic-region-100578325",false,"NCT06809829","Evaluation of Doxycycline Nanoparticle With Gelatin Sponge on Immediate Implant in Esthetic Region","Clinical and Radiographic Evaluation of Doxycycline and Doxycycline Loaded Nanoparticles With Gelatin Sponge on Immediate Implant Placement in Esthetic Zone: A Randomized Clinical Trial","Inclusion Criteria:\n\n* The presence of non-restorable single-rooted maxillary centrals, canines or premolars.\n* Sufficient bone volume.\n* Good oral hygiene.\n* The remaining space between the socket and the fixture equals or more than 2mm at the coronal third of the socket.\n* Sufficient bone width (≥ 1 mm) in the buccal plate of the remaining bone to place an implant confirmed by cone beam computer tomography (CBCT).\n\nExclusion Criteria:\n\n* Insufficient bone volume.\n* Active infection.\n* Patients on chemotherapy or radiotherapy.\n* Patients who have systemic disorders {uncontrolled diabetes mellitus, autoimmune disease, …etc},\n* Pregnant patients,\n* Patients with bone diseases\n* Presence of periapical pathology affecting the neighbouring teeth.\n* Smokers.","ALL","18 Years","50 Years",{"count":53,"type":54},16,"ESTIMATED","INTERVENTIONAL",[57],"NA","The goal of this clinical trial is to Evaluate the effect of Doxycycline nanoparticles along with gelatin sponge in immediate implant cases in esthetic zone. The main question it aims to answer is:\n\nDoes the application of doxycycline nanoparticles with gelatin sponge improve the clinical and radiographic outcomes of immediate implant cases in esthetic zone?\n\nResearchers will compare eight patients undergoing immediate implant placement with the buccal gap filled with doxycycline loaded gelatin nanoparticles along with gelatin sponge (group A) with eight patients undergoing immediate implant placement with the buccal gap filled with doxycycline along with gelatin sponge (group B). to see if the doxycycline loaded nanoparticles will improve the clinical and radiographic outcomes of the immediate implant .\n\nParticipants will \\[describe the main tasks participants will be asked to do, interventions they'll be given and use bullets if it is more than 2 items\\].",[21],[21,61,62,63],"Nanoparticles","Doxycycline","Gelatin Sponge","2025-02-04",{"date":66,"type":67},"2025-02-05","ACTUAL",{"date":69,"type":54},"2025-02",{"date":71,"type":54},"2027-02",{"name":5,"class":6},1]