[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100616345":3},{"organization":4,"armGroups":7,"interventions":10,"overallOfficials":10,"centralContacts":12,"locations":20,"responsibleParty":94,"collaborators":96,"id":100,"slug":101,"hasResults":102,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":106,"eligibilityCriteria":107,"healthyVolunteers":102,"sex":108,"minAge":109,"maxAge":10,"enrollmentInfo":110,"targetDuration":10,"studyType":113,"phases":10,"briefSummary":114,"conditions":115,"keywords":118,"overallStatus":22,"whyStopped":10,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":133,"locationsCount":134},{"fullName":5,"class":6},"Rijnstate Hospital","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":10},"Patients with painful chemotherapy induced peripheral neuropathy (CIPN)",null,"Subjects diagnosed with painful CIPN and eligible for SCS implantation",[13,18],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},"Esmee Van Leeuwen, MSc","CONTACT","088 005 8888","evanleeuwen@rijnstate.nl",{"name":19,"role":15,"phone":10,"phoneExt":10,"email":10},"Nick Koning, MD PhD",[21,42,55,68,81],{"facility":5,"status":22,"city":23,"state":10,"zip":24,"country":25,"countryCode":26,"cosmosGeoPoint":27,"geoPoint":32,"contacts":33},"RECRUITING","Arnhem","6815 AD","Netherlands","NL",{"type":28,"coordinates":29},"Point",[30,31],5.91111,51.98,{"lat":31,"lon":30},[34,35,37,40],{"name":14,"role":15,"phone":16,"phoneExt":10,"email":17},{"name":10,"role":15,"phone":10,"phoneExt":10,"email":36},"jkallewaard@rijnstate.nl",{"name":38,"role":39,"phone":10,"phoneExt":10,"email":10},"Nick J Koning, MD PhD","PRINCIPAL_INVESTIGATOR",{"name":41,"role":39,"phone":10,"phoneExt":10,"email":10},"Jan Willem Kallewaard, MD PhD",{"facility":43,"status":22,"city":44,"state":10,"zip":10,"country":25,"countryCode":26,"cosmosGeoPoint":45,"geoPoint":49,"contacts":50},"Sint Antonius Ziekenhuis","Nieuwegein",{"type":28,"coordinates":46},[47,48],5.08056,52.02917,{"lat":48,"lon":47},[51],{"name":52,"role":15,"phone":53,"phoneExt":10,"email":54},"Harold Nijhuis, MD","+3188 320 3000","h.nijhuis@antoniusziekenhuis.nl",{"facility":56,"status":22,"city":57,"state":10,"zip":10,"country":25,"countryCode":26,"cosmosGeoPoint":58,"geoPoint":62,"contacts":63},"Bravis Hospital","Roosendaal",{"type":28,"coordinates":59},[60,61],4.46528,51.53083,{"lat":61,"lon":60},[64],{"name":65,"role":15,"phone":66,"phoneExt":10,"email":67},"Lars Elzinga, MD","+3188 706 8000","l.elzinga@bravis.nl",{"facility":69,"status":22,"city":70,"state":10,"zip":10,"country":25,"countryCode":26,"cosmosGeoPoint":71,"geoPoint":75,"contacts":76},"ETZ","Tilburg",{"type":28,"coordinates":72},[73,74],5.0913,51.55551,{"lat":74,"lon":73},[77],{"name":78,"role":15,"phone":79,"phoneExt":10,"email":80},"Johan van de Minkelis, MD","+3113 221 0000","jl.vandeminkelis@etz.nl",{"facility":82,"status":22,"city":83,"state":10,"zip":10,"country":25,"countryCode":26,"cosmosGeoPoint":84,"geoPoint":88,"contacts":89},"ASZ","Zwijndrecht",{"type":28,"coordinates":85},[86,87],4.63333,51.8175,{"lat":87,"lon":86},[90],{"name":91,"role":15,"phone":92,"phoneExt":10,"email":93},"Hans Aukes, MD","+3178654 22 19","h.aukes@asz.nl",{"type":95,"investigatorFullName":10,"investigatorTitle":10,"investigatorAffiliation":10,"oldNameTitle":10,"oldOrganization":10},"SPONSOR",[97],{"name":98,"class":99},"Saluda Medical Pty Ltd","INDUSTRY","100616345","evaluation-of-effectiveness-of-closed-loop-spinal-cord-stimulation-cl-scs-therapy-for-treatment-of-chemotherapy-induced-peripheral-neuropathy-100616345",false,"NCT07304401","Evaluation of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy for Treatment of Chemotherapy Induced Peripheral Neuropathy","Assessment of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy on Pain Reduction and Improvement of Quality of Life in Patients With Chemotherapy Induced Peripheral Neuropathy","CIPRESS","* Subject is deemed a suitable candidate for SCS implantation and has been routinely scheduled to undergo an SCS implantation with the Evoke SCS System.\n* Subject has a minimum of leg or arm pain intensity of 5\u002F10 on the numeric rating scale (NRS) at baseline due to CIPN.\n* Patients with CIPN following chemotherapy and at least 6 months post-treatment\n* CIPN symptoms for a minimum duration of 3 months.\n* Patient deemed to be in remission per discretion of treating oncologist\n* No existing contraindications for SCS\n* Subject is ≥ 18 years old.\n* Subject is not pregnant or nursing.\n* Subject is willing and capable of giving informed consent.\n* No satisfactory treatment effect with anti-neuropathic medication or intolerable side-effects\n* No satisfactory treatment effect with minimal invasive pain treatments (including ketamine or lidocaine infusion therapy)\n\nExclusion Criteria:\n\n* Patient refusal to be included in study\n* Patients unwilling or mentally incapable to complete the study questionnaires\n* Other causes of neuropathy (for example diabetic- or small fiber neuropathy)\n* Previous treatment with SCS for CIPN\n* Presence of another pain syndrome unrelated to CIPN\n* History of lower limb amputation or ulceration\n* Body mass index (BMI) ≥ 40\n* Severe psychiatric or neurological disorders\n* Any other contra indication for locoregional anaesthesia","ALL","18 Years",{"count":111,"type":112},20,"ESTIMATED","OBSERVATIONAL","The goal of this observational study is to learn about the effectiveness of closed-loop spinal cord stimulation (CL-SCS) therapy for treatment of painful chemotherapy induced peripheral neuropathy.\n\nThe closed-loop SCS (CL-SCS) system stimulates the nerves in the spinal cord, measures their responses and automatically adjust the stimulation level accordingly in real time for each delivered pulse.",[116,117],"Chemotherapy Induced Peripheral Neuropathy (CIPN)","Neuropathic Pain",[119,120,121,122,123,124],"CIPN","Chemotherapy induced peripheral neuropathy","Spinal Cord Stimulation","SCS","Closed-Loop","neuropathic pain","2025-12-24",{"date":127,"type":128},"2025-12-26","ACTUAL",{"date":130,"type":112},"2025-12-01",{"date":132,"type":112},"2028-12-01",{"name":5,"class":6},5]