[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100612567":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":20,"centralContacts":21,"locations":30,"responsibleParty":135,"collaborators":20,"id":137,"slug":138,"hasResults":139,"nctId":140,"briefTitle":141,"officialTitle":142,"acronym":20,"eligibilityCriteria":143,"healthyVolunteers":144,"sex":145,"minAge":146,"maxAge":20,"enrollmentInfo":147,"targetDuration":20,"studyType":150,"phases":151,"briefSummary":153,"conditions":154,"keywords":20,"overallStatus":33,"whyStopped":20,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":169},{"fullName":5,"class":6},"Symatese","INDUSTRY",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Aesthetic treatment with hyaluronic acid (HA) of one or more regions of the face.","EXPERIMENTAL","Based on their preferences and with the agreement of the healthcare professional, subjects may receive aesthetic treatments of the lips, perioral lines, nasolabial folds, cheeks, and\u002For infraorbital hollows.",[13],"Device: Facial injection of hyaluronic acid-based dermal fillers.",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":20},"DEVICE","Facial injection of hyaluronic acid-based dermal fillers.","Facial injection of hyaluronic acid-based dermal fillers USING COLD-X™ TECHNOLOGY by Symatese.",[9],null,[22,27],{"name":23,"role":24,"phone":25,"phoneExt":20,"email":26},"Valentin BONVALET","CONTACT","+33 (0)4 78 56 72 80","v.bonvalet@symatese.com",{"name":28,"role":24,"phone":25,"phoneExt":20,"email":29},"Sébastien GUYON","s.guyon@symatese.com",[31,49,63,74,88,102,112,122],{"facility":32,"status":33,"city":34,"state":20,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":38,"geoPoint":43,"contacts":44},"Centre Médical Saint Jean","RECRUITING","Arras","62000","France","FR",{"type":39,"coordinates":40},"Point",[41,42],2.78186,50.29301,{"lat":42,"lon":41},[45],{"name":46,"role":24,"phone":47,"phoneExt":20,"email":48},"Cyril Maire","+33 3 21 71 34 34","maire.dermatologie@hotmail.fr",{"facility":50,"status":33,"city":51,"state":20,"zip":52,"country":36,"countryCode":37,"cosmosGeoPoint":53,"geoPoint":57,"contacts":58},"Cabinet médical","Lyon","69005",{"type":39,"coordinates":54},[55,56],4.84789,45.74906,{"lat":56,"lon":55},[59],{"name":60,"role":24,"phone":61,"phoneExt":20,"email":62},"Amandine CATELAIN-LAMY","+33 4 78 36 85 85","amandinelamy28@icloud.com",{"facility":64,"status":33,"city":51,"state":20,"zip":65,"country":36,"countryCode":37,"cosmosGeoPoint":66,"geoPoint":68,"contacts":69},"Palais de Flore","69006",{"type":39,"coordinates":67},[55,56],{"lat":56,"lon":55},[70],{"name":71,"role":24,"phone":72,"phoneExt":20,"email":73},"Sophie Converset","+33 4 78 41 88 85","drconverset@gmail.com",{"facility":75,"status":33,"city":76,"state":20,"zip":77,"country":36,"countryCode":37,"cosmosGeoPoint":78,"geoPoint":82,"contacts":83},"Centre Laser Palaiseau","Palaiseau","91120",{"type":39,"coordinates":79},[80,81],2.2498,48.71828,{"lat":81,"lon":80},[84],{"name":85,"role":24,"phone":86,"phoneExt":20,"email":87},"Diala Haykal","+33 1 60 10 64 55","docteur.haykal@gmail.com",{"facility":89,"status":33,"city":90,"state":20,"zip":91,"country":36,"countryCode":37,"cosmosGeoPoint":92,"geoPoint":96,"contacts":97},"Aesthé - Marais.","Paris","75004",{"type":39,"coordinates":93},[94,95],2.3488,48.85341,{"lat":95,"lon":94},[98],{"name":99,"role":24,"phone":100,"phoneExt":20,"email":101},"Arnaud Lambert","+33 1 40 61 91 58","aldermoaesthetic@gmail.com",{"facility":50,"status":33,"city":90,"state":20,"zip":103,"country":36,"countryCode":37,"cosmosGeoPoint":104,"geoPoint":106,"contacts":107},"75008",{"type":39,"coordinates":105},[94,95],{"lat":95,"lon":94},[108],{"name":109,"role":24,"phone":110,"phoneExt":20,"email":111},"Jean-Jacques DEUTSCH","+33 1 47 20 05 03","deutschjj@gmail.com",{"facility":50,"status":33,"city":90,"state":20,"zip":113,"country":36,"countryCode":37,"cosmosGeoPoint":114,"geoPoint":116,"contacts":117},"75116",{"type":39,"coordinates":115},[94,95],{"lat":95,"lon":94},[118],{"name":119,"role":24,"phone":120,"phoneExt":20,"email":121},"Sylvie Poignonec","+33 1 45 63 13 20","sylvie@poignonec.com",{"facility":50,"status":33,"city":123,"state":20,"zip":124,"country":36,"countryCode":37,"cosmosGeoPoint":125,"geoPoint":129,"contacts":130},"Saint-Maur-des-Fossés","94100",{"type":39,"coordinates":126},[127,128],2.49323,48.79395,{"lat":128,"lon":127},[131],{"name":132,"role":24,"phone":133,"phoneExt":20,"email":134},"Elisabeth DOMERGUE THAN TRONG","+33 1 42 83 38 18","elisabeth.domergue.than.trong@gmail.com",{"type":136,"investigatorFullName":20,"investigatorTitle":20,"investigatorAffiliation":20,"oldNameTitle":20,"oldOrganization":20},"SPONSOR","100612567","evaluation-of-facial-ha-dermal-fillers-in-real-life-conditions-100612567",false,"NCT07255261","Evaluation of Facial HA Dermal Fillers in Real-Life Conditions","Post-Marketing Clinical Follow Up On Hyaluronic Acid-Based Dermal Fillers Using COLD-X™ Technology By Symatese","Inclusion Criteria:\n\n* Subject seeking an aesthetic correction of the infraorbital hollows with FASY P and\u002F or an aesthetic correction of the lips with ESTYME® LIPS, and\u002F or an aesthetic correction of the perioral lines with ESTYME® SMOOTH, and\u002F or an aesthetic correction of nasolabial folds with ESTYME® SMOOTH, and\u002F or an aesthetic correction of cheeks with ESTYME® SCULPT.\n* Subject who agreed to participate and have signed an informed consent.\n* Age: over 18 years old.\n* Subject being affiliated to a health social security system.\n\nExclusion Criteria:\n\n* Minors\n* Subjects with a known allergy to hyaluronic acid, lidocaine or amide local anesthetics.\n* Subjects with porphyria.\n* Subjects with an autoimmune disorder, or using an immunosuppressant medication.\n* Pregnant or breastfeeding women.\n* Subjects with inflammation, infection or cutaneous disorders, at the treatment site or nearby.\n* Subjects with bleeding disorders or in subjects receiving thrombolytic or anticoagulant treatment.\n* Areas other than those recommended by the IFU.\n* Subject deprived of liberty by judicial or administrative decision.\n* Adults under a legal protection measure (guardianship\u002Fcuratorship).\n* Subject under legal protection order.",true,"ALL","18 Years",{"count":148,"type":149},460,"ESTIMATED","INTERVENTIONAL",[152],"NA","The goal of this post-market interventional study is to confirm, under real-life conditions, the safety and performance of hyaluronic acid-based dermal fillers intended to modify skin anatomy and facial appearance. Subjects aged 18 years or older seeking aesthetic treatment of the lips, perioral lines, nasolabial folds, cheeks, and\u002For infraorbital hollows may be included. The main question the study aims to answer is: How long does the effect of the products last?\n\nParticipants will attend follow-up visits every 6 months after the initial injection, until the end of follow-up at 24 months. During each visit, the investigator will assess performance and safety through a simple clinical examination. At each follow-up visit, subjects will also evaluate the aesthetic improvement compared with their pre-injection appearance. Subjects will be asked about the level of pain experienced during the initial injection.\n\nIf the subject wishes, a retreatment may be performed at the 12-month or 18-month follow-up visit, provided that the treated area(s) have returned to the pre-injection state.",[155,156,157,158,159],"Lips Enhancement","Perioral Wrinkles","Nasolabial Fold Wrinkles","Cheek Augmentation","Infraorbital Hollows","2025-12-01",{"date":162,"type":163},"2025-12-08","ACTUAL",{"date":165,"type":163},"2025-07-02",{"date":167,"type":149},"2028-07",{"name":5,"class":6},8]