[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100538726":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":39,"responsibleParty":59,"collaborators":25,"id":62,"slug":63,"hasResults":64,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":25,"eligibilityCriteria":68,"healthyVolunteers":69,"sex":70,"minAge":71,"maxAge":25,"enrollmentInfo":72,"targetDuration":25,"studyType":75,"phases":76,"briefSummary":78,"conditions":79,"keywords":82,"overallStatus":42,"whyStopped":25,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":94},{"fullName":5,"class":6},"University of Alabama at Birmingham","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"FGG before GBR","EXPERIMENTAL","Free Gingival Graft(FGG) before the guided bone regeneration(GBR)",[13],"Procedure: FGG Before GBR",{"label":15,"type":10,"description":16,"interventionNames":17},"FGG after GBR","Free Gingival Graft(FGG) after the guided bone regeneration(GBR)",[18],"Procedure: FGG after GBR",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"PROCEDURE","FGG Before GBR","Free Gingival Graft before the guided bone regeneration,",[9],null,{"type":21,"name":15,"description":27,"armGroupLabels":28,"otherNames":25},"Free Gingival Graft after the guided bone regeneration,",[15],[30,35],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Hussein Basma, DDS, MS","CONTACT","205-975-2888","basma86@uab.edu",{"name":36,"role":32,"phone":37,"phoneExt":25,"email":38},"Sarah Startley, DMD","205-975-8711","ss1971@uab.edu",[40],{"facility":41,"status":42,"city":43,"state":44,"zip":45,"country":46,"countryCode":47,"cosmosGeoPoint":48,"geoPoint":53,"contacts":54},"Unversity of Alabama at Birmingham, School of Dentistry","RECRUITING","Birmingham","Alabama","35294-0007","United States","US",{"type":49,"coordinates":50},"Point",[51,52],-86.80249,33.52066,{"lat":52,"lon":51},[55,56,57],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"name":36,"role":32,"phone":37,"phoneExt":25,"email":38},{"name":31,"role":58,"phone":25,"phoneExt":25,"email":25},"PRINCIPAL_INVESTIGATOR",{"type":58,"investigatorFullName":60,"investigatorTitle":61,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"Hussein Basma","Clinical Assistant Professor, Principal Investigator","100538726","evaluation-of-free-gingival-graft-timing-100538726",false,"NCT06294587","Evaluation of Free Gingival Graft Timing","Evaluation of Free Gingival Graft Timing in Staged Guided Bone Regeneration: A Randomized Controlled Trial","Inclusion Criteria:\n\n* • At least 18 years old\n\n  * No uncontrolled medical conditions or medications that will affect their bone healing.\n  * Good oral hygiene is defined as a full-mouth plaque score ≤25%11.\n  * Must be able to read and understand the informed consent document.\n  * Has a need for implants to replace missing tooth\u002Fteeth in at least 1 quadrant of the mouth.\n  * Insufficient alveolar ridge width for endosseous implant placement, defined as 5 mm or less, as determined by bone sounding and CBCT scan.\n  * The patient and\u002For guardian is willing and able to comply with pre-operative and post-operative diagnostic and clinical evaluations required.\n  * The patient is not pregnant or breastfeeding.\n\nExclusion Criteria:\n\n* Active infectious diseases.\n\n  * Liver or kidney dysfunction\u002Ffailure.\n  * Uncontrolled diabetes (HbA1c ≥ 8.5).\n  * Active cancer treatment - such as active chemotherapy radiation therapy, or radiotherapy performed within ≤12 months from the procedure.\n  * Taking medications that will affect their bone healing (for example, bisphosphonates and long-term anti-inflammatory medications).\n  * Metabolic bone diseases that affect bone healing such as osteoporosis.\n  * Pregnant or lactating women (self-reported).\n  * Current tobacco and Marijuana smokers have 10 or more cigarettes per day, and former smokers (\\> 10 cigarettes) who quit \\< 10 ago (self-reported).\n  * Poor oral hygiene.\n  * Vertical loss of bone at the edentulous ridge.\n  * History of periodontal disease.\n  * The patient is pregnant or breastfeeding",true,"ALL","18 Years",{"count":73,"type":74},30,"ESTIMATED","INTERVENTIONAL",[77],"NA","This clinical trial aims to compare and evaluate the clinical outcomes between two distinct treatment sequences: free gingival graft surgery preceding guided bone regeneration and guided bone regeneration followed by free gingival graft.",[80,81],"Ridge Augmentation","Alveolar Mucosa",[80,83,84],"Attached mucosa","Dental implants","2025-08-04",{"date":87,"type":88},"2025-08-06","ACTUAL",{"date":90,"type":88},"2024-08-12",{"date":92,"type":74},"2027-08-30",{"name":5,"class":6},1]