[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100633040":3},{"organization":4,"armGroups":7,"interventions":13,"overallOfficials":18,"centralContacts":25,"locations":31,"responsibleParty":38,"collaborators":10,"id":42,"slug":43,"hasResults":44,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":44,"sex":50,"minAge":51,"maxAge":10,"enrollmentInfo":52,"targetDuration":10,"studyType":55,"phases":56,"briefSummary":58,"conditions":59,"keywords":63,"overallStatus":68,"whyStopped":10,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":78},{"fullName":5,"class":6},"Cairo University","OTHER",[8],{"label":9,"type":6,"description":10,"interventionNames":11},"GTR with Autogenous Bone Chips and CGF Membrane",null,[12],"Other: concentrated growth factor (CGF) Membrane",[14],{"type":6,"name":15,"description":16,"armGroupLabels":17,"otherNames":10},"concentrated growth factor (CGF) Membrane","This is a third-generation autologous blood concentrate prepared using a dedicated centrifuge system. The process creates a fibrin-rich organic matrix from the patient's own blood, which is then molded into a membrane and packed over the grafted bone to enhance bone density increase and improvement of the surrounding tissue.",[9],[19,22],{"name":20,"affiliation":5,"role":21},"Hesham Elsayed Elhawary, Professor","STUDY_CHAIR",{"name":23,"affiliation":5,"role":24},"Abdelmoez Mohamed El-Sharkawy, Assistant Professor","STUDY_DIRECTOR",[26],{"name":27,"role":28,"phone":29,"phoneExt":29,"email":30},"meis youssef moustafa, bachelors","CONTACT","00201065186643","meis.eltanany@dentistry.cu.edu.eg",[32],{"facility":5,"status":10,"city":33,"state":34,"zip":35,"country":36,"countryCode":37,"cosmosGeoPoint":10,"geoPoint":10,"contacts":10},"Giza","Cairo Governorate","12511","Egypt","EG",{"type":39,"investigatorFullName":40,"investigatorTitle":41,"investigatorAffiliation":5,"oldNameTitle":10,"oldOrganization":10},"PRINCIPAL_INVESTIGATOR","Meis Youssef Moustafa","principle investigator","100633040","evaluation-of-guided-tissue-regeneration-with-autogenous-bone-chips-and-cgf-during-implant-placement-100633040",false,"NCT07521514","Evaluation of Guided Tissue Regeneration With Autogenous Bone Chips and CGF During Implant Placement","Clinical and Radiographic Evaluation of Guided Tissue Regeneration Using Autogenous Bone Chips and Concentrated Growth Factors Membranes With Simultaneous Implant Placement. (Case Series)","CGF","inclusion criteria:\n\n* A medical history that contraindicates oral surgical treatment such as (uncontrolled\u002Funtreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and\u002For intravenous bisphosphonates).\n* Presence of active or untreated periodontal disease.\n* Vertical root fractures involving the buccal aspect.\n* Tooth \u002Fteeth with horizontal fractures below bone level.\n* Tooth \u002Fteeth with external or internal resorption.\n* Patients with destructive oral habits such as smoking, chewing tobacco, bruxism,etcetera(Chrcanovic et al., 2014).\n\nexclusion criteria: A medical history that contraindicates oral surgical treatment such as (uncontrolled\u002Funtreated diabetes mellitus, immuno-compromised status, radio or chemotherapy of the oral and maxillofacial region, treatment with oral and\u002For intravenous bisphosphonates).\n\n* Presence of active or untreated periodontal disease.\n* Vertical root fractures involving the buccal aspect.\n* Tooth \u002Fteeth with horizontal fractures below bone level.\n* Tooth \u002Fteeth with external or internal resorption.\n* Patients with destructive oral habits such as smoking, chewing tobacco, bruxism, etcetera(Chrcanovic et al., 2014).","ALL","18 Years",{"count":53,"type":54},8,"ESTIMATED","INTERVENTIONAL",[57],"NA","CGF membranes will be prepared using a swing-lock centrifuge. A full-thickness mucoperiosteal flap will be elevated in a narrow alveolar ridge. Implants will be inserted. Autologous bone chips will be harvested via bone scraping and used for augmentation, CGF membranes will be placed over the grafted area. Suturing of the mucoperiosteal flap. Radiographic evaluation of the bone density and tissue thickness will be performed by CBCT preoperatively, immediate postoperative and after the procedure by 4 months. Clinical evaluation of the tissue thickness using periodontal probe preoperatively, immediate postoperatively and after the procedure by 4 months",[60,61,62],"Alveolar Bone Loss","Alveolar Ridge Augmentation","Dental Implant",[48,64,65,66,67],"autogenous bone graft","gingival biotype","dental implant","guided tissue regeneration","NOT_YET_RECRUITING","2026-04-08",{"date":71,"type":72},"2026-04-13","ACTUAL",{"date":74,"type":54},"2026-04-16",{"date":76,"type":54},"2026-10",{"name":5,"class":6},1]