[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100557106":3},{"organization":4,"armGroups":7,"interventions":7,"overallOfficials":7,"centralContacts":7,"locations":7,"responsibleParty":8,"collaborators":7,"id":12,"slug":13,"hasResults":14,"nctId":15,"briefTitle":16,"officialTitle":17,"acronym":18,"eligibilityCriteria":19,"healthyVolunteers":14,"sex":20,"minAge":21,"maxAge":7,"enrollmentInfo":22,"targetDuration":7,"studyType":25,"phases":7,"briefSummary":26,"conditions":27,"keywords":7,"overallStatus":29,"whyStopped":7,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":7},{"fullName":5,"class":6},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",null,{"type":9,"investigatorFullName":10,"investigatorTitle":11,"investigatorAffiliation":5,"oldNameTitle":7,"oldOrganization":7},"PRINCIPAL_INVESTIGATOR","De Maio Flavio","Principal Investigator","100557106","evaluation-of-gut-microbiota-and-its-associated-resistome-in-fmt-donors-and-recipients-due-to-recurrent-clostridiodes-difficile-infection-100557106",false,"NCT06533800","Evaluation of Gut Microbiota and Its Associated Resistome in FMT Donors and Recipients Due to Recurrent Clostridiodes Difficile Infection","VALUTAZIONE DEL MICROBIOTA E DEL RESISTOMA NEI DONATORI E NEI RICEVENTI DI FMT IN PAZIENTI CON INFEZIONE RICORRENTE DA CLOSTRIDIOIDES DIFFICILE","MICROFMT","Inclusion criteria\n\n* patients with rCDI (\\> 18 years) to whom faecal microbiota transplantation is indicated, without other pathologies or prolonged hospitalization periods\n* donors: healthy volunteers aged between 18 and 50 years\n* Patients capable of expressing consent\n\nExclusion criteria\n\n* antibiotic therapies in the last 30 days\n* treatments with prebiotics - probiotics - postbiotics in the last 60 days\n* colonization by MDR or XDR pathogens\n* presence of pre-existing or ongoing intestinal pathologies (Inflammatory Intestinal Diseases, chronic hepatitis, celiac disease, neoplasms, previous large intestinal resections)\n* ongoing diarrhea of any origin (defined as more than 6 watery stools per day and\u002For faecal volume greater than 250 ml in 24 hours)\n* severe septic state in progress\n* for donors: drug addiction, promiscuous sexual behaviour, use of drugs that can be excreted in the faeces with potential risk for recipients","ALL","18 Years",{"count":23,"type":24},24,"ESTIMATED","OBSERVATIONAL","Caratterizzazione della composizione microbica intestinale nei donatori di FMT e nei pazienti affetti da rCDI al tempo basale e a seguito del trapianto di microbiota fecale. Negli stessi time point valutare il resistoma associato alla comunità microbica rilevata.",[28],"CDI","NOT_YET_RECRUITING","2024-07-30",{"date":32,"type":33},"2024-08-01","ACTUAL",{"date":35,"type":24},"2024-09-15",{"date":37,"type":24},"2026-08-15",{"name":5,"class":6}]