[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100621263":3},{"organization":4,"armGroups":7,"interventions":19,"overallOfficials":25,"centralContacts":29,"locations":35,"responsibleParty":49,"collaborators":25,"id":53,"slug":54,"hasResults":55,"nctId":56,"briefTitle":57,"officialTitle":57,"acronym":58,"eligibilityCriteria":59,"healthyVolunteers":55,"sex":60,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":25,"studyType":66,"phases":67,"briefSummary":69,"conditions":70,"keywords":72,"overallStatus":38,"whyStopped":25,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":83},{"fullName":5,"class":6},"Kafrelsheikh University","OTHER",[8,14],{"label":9,"type":10,"description":11,"interventionNames":12},"Nasoseptal Flap for Endoscopic Skull","EXPERIMENTAL","• Group A: Free graft + Internal nasal splint\n\n* Free graft material (e.g., fascia lata, fat, synthetic dural substitute) placed over the defect.\n* Internal nasal splint applied to support the graft and maintain its position",[13],"Device: Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks",{"label":15,"type":10,"description":16,"interventionNames":17},"Evaluation of Internal Nasal Splint-Supported Free Graft in Endoscopic Skul","• Group B: Nasoseptal flap alone.\n\n\\- Standard nasoseptal flap technique used for skull base repair.",[18],"Device: Internal Nasal Splint-Supported Free Graft",[20,26],{"type":21,"name":22,"description":23,"armGroupLabels":24,"otherNames":25},"DEVICE","Internal Nasal Splint-Supported Free Graft","Evaluation of Internal Nasal Splint-Supported Free Graft versus Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks",[15],null,{"type":21,"name":27,"description":27,"armGroupLabels":28,"otherNames":25},"Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks",[9],[30],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},"Amr Maher Shady, resident","CONTACT","0473109517","amrshady00@gmail.com",[36],{"facility":37,"status":38,"city":39,"state":40,"zip":41,"country":42,"countryCode":43,"cosmosGeoPoint":25,"geoPoint":25,"contacts":44},"Kafrelsheikh Faculty of Medicine","RECRUITING","Kafr Elsheikh","Kafrelsheikh","33155.","Egypt","EG",[45,46],{"name":31,"role":32,"phone":33,"phoneExt":25,"email":34},{"name":47,"role":32,"phone":25,"phoneExt":25,"email":48},"Saad Elzayat Kafr Elsheikh Hospital University, professor","saad_hilmy@med.kfs.edu.eg",{"type":50,"investigatorFullName":51,"investigatorTitle":52,"investigatorAffiliation":5,"oldNameTitle":25,"oldOrganization":25},"PRINCIPAL_INVESTIGATOR","Amr Mahr Shady","resident","100621263","evaluation-of-internal-nasal-splint-supported-free-graft-versus-nasoseptal-flap-for-endoscopic-skull-base-repair-in-cerebrospinal-fluid-leaks-100621263",false,"NCT07368348","Evaluation of Internal Nasal Splint-Supported Free Graft Versus Nasoseptal Flap for Endoscopic Skull Base Repair in Cerebrospinal Fluid Leaks","CSF","Inclusion Criteria: 1- Adults (≥18 years). 2- Patients with bilateral CSF leaks confirmed by imaging and biochemical testing (e.g., beta-2 transferrin).\n\n3- Patients with bilateral CSF leak and sever septal spur. 4- Patients with bilateral CSF leak and history of submucosal resection of nasal septum.\n\n5- Patients with bilateral CSF leak and large septal perforation. 6- Patients with bilateral CSF Leak and septal granuloma.\n\nExclusion Criteria: 1- Patients with contraindications to endoscopic surgery. 2- Active sinus or nasal infections. 3- Previous nasal or skull base surgery affecting the repair site.\n\n\\-","ALL","18 Years","70 Years",{"count":64,"type":65},20,"ESTIMATED","INTERVENTIONAL",[68],"NA","The study aims to compare the feasibility and effectiveness of using an internal nasal splint- supported free graft versus a nasoseptal flap alone for endoscopic repair of bilateral CSF leaks.\n\nResearch question:\n\nDoes the use of an internal nasal splint to support a free graft during endoscopic repair of bilateral CSF leaks improve outcomes compared to the use of a nasoseptal flap alone?",[71],"CSF Leak",[73],"CSF, Stent","2026-05-23",{"date":76,"type":77},"2026-05-27","ACTUAL",{"date":79,"type":77},"2026-02-01",{"date":81,"type":65},"2026-11-01",{"name":5,"class":6},1]