[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-study-detail:100592540":3},{"organization":4,"armGroups":7,"interventions":14,"overallOfficials":11,"centralContacts":20,"locations":26,"responsibleParty":45,"collaborators":11,"id":48,"slug":49,"hasResults":50,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":50,"sex":56,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":11,"studyType":62,"phases":63,"briefSummary":65,"conditions":66,"keywords":69,"overallStatus":29,"whyStopped":11,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},{"fullName":5,"class":6},"Cairo University","OTHER",[8],{"label":9,"type":10,"description":11,"interventionNames":12},"Bilateral cleft lip and palate patients","EXPERIMENTAL",null,[13],"Device: clear aligners",[15],{"type":16,"name":17,"description":18,"armGroupLabels":19,"otherNames":11},"DEVICE","clear aligners","aligners made with 1mm thickness sheet and covering the whole palate",[9],[21],{"name":22,"role":23,"phone":24,"phoneExt":11,"email":25},"mahmoud Abo-Salem, M.SC","CONTACT","+201112052622","mahmoud.abdelsalam@dentistry.cu.edu.eg",[27],{"facility":28,"status":29,"city":30,"state":31,"zip":32,"country":33,"countryCode":34,"cosmosGeoPoint":35,"geoPoint":40,"contacts":41},"Faculty of Dentistry - Cairo University","RECRUITING","Cairo","Select","11511","Egypt","EG",{"type":36,"coordinates":37},"Point",[38,39],31.24967,30.06263,{"lat":39,"lon":38},[42],{"name":43,"role":23,"phone":44,"phoneExt":11,"email":25},"mahmoud abdelsalam","01112052622",{"type":46,"investigatorFullName":43,"investigatorTitle":47,"investigatorAffiliation":5,"oldNameTitle":11,"oldOrganization":11},"PRINCIPAL_INVESTIGATOR","Master degree candidate at Orthodontic Department","100592540","evaluation-of-maxillary-expansion-using-clear-aligners-therapy-in-patients-with-cleft-lip-and-palate-at-the-mixed-dentition-stage-100592540",false,"NCT06994754","Evaluation of Maxillary Expansion Using Clear Aligners' Therapy in Patients With Cleft Lip and Palate at the Mixed Dentition Stage","Evaluation of Maxillary Expansion Using Clear Aligners' Therapy in Patients With Cleft Lip and Palate at the Mixed Dentition Stage: A Pilot Study","Pilot","Inclusion Criteria:\n\n* Mixed dentition.\n* Both males and females.\n* Bilateral cleft lip and palate.\n* Lip repair performed between 3 and 6 months of age and palate repair performed between 12and 24 months of age.\n* Presence of maxillary constriction that needs maxillary expansion.\n* Good periodontal health.\n* No previous orthodontic treatment.\n\nExclusion Criteria:\n\n* Syndromic cleft lip and palate patients.\n* Taking medications that influence growth.","ALL","6 Years","12 Years",{"count":60,"type":61},10,"ESTIMATED","INTERVENTIONAL",[64],"NA","The goal of this clinical trial is to learn if the aligners can expand upper dental arch in patients with cleft lip and palate at age of 6-8 years old to correct their collapsid archs. The main questions it aims to answer are:\n\nDoes aligners can achieve transverse dento-skeletal changes? Does aligners can achieve anteroposterior and vertical dento-skeletal changes?\n\nParticipants will:\n\nWear sequence of aligners (each for 10 days). Visit the clinic every month for checkups. 3D x-ray and intraoral scan will be taken after completion of the aligners set to evaluate the intervention.",[67,68],"Maxillary Deficiency","Cleft Lip and Palate",[70],"Maxillary Expansion by Aligners","2025-06-09",{"date":73,"type":74},"2025-06-12","ACTUAL",{"date":76,"type":74},"2025-04-06",{"date":78,"type":61},"2026-12",{"name":5,"class":6},1]